Numerical study of subcooled and saturated flow boiling in the curved and helically  coiled tubes in presence of phase change is one of the challenging area of CFD studies. In this paper, the CFD modeling of the nucleate and convective flow boiling in the small helically coiled tube at low vapor quality (up to the 18.93 percent) region is studied. A proper Eulerian-based mathematical model is used for interphase exchange forces and heat transfer between two phases in CFD modeling using Bulk boiling model. The results show that, the inner and the bottom wall of the helically coiled tube have the lowest and the highest heat transfer coefficient, respectively. The effect of change in coil diameter, helical pitch and tube diameter is investigated on the counters of vapor volume fraction. It is seen that at low vapor quality flows, the heat transfer coefficient is enhanced by decreasing in coil diameter, tube diameter and increasing in coil pitch of helically coiled tube. 

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.

This study discusses prospects and challenges facing start-up entrepreneurs in language and culture-related tourist attractions in Lombok, Indonesia. Data were collected by observing the operations of tourism entrepreneurs and interviewing the owners, workers, clients, and authorities in the industry. The data were analyzed using a mixed method where tourism sales over one year of business experience were quantitatively analyzed and where prime causes leading to profits and losses were qualitatively explicated. The findings identify six prospective opportunities and five challenges in sustainably establishing language and culture-related tourist attractions as core entrepreneurial businesses. This study enriches our understanding of what micro and small entrepreneurs experience at the early stages of business start-ups and how they respond to uncertainties facing them. The study also provides readers with an understanding of the prospects and the challenges facing small tourist-related entrepreneurs in operations at early start-up stages and serves as a reminder to small businesses about the potential challenges in their business operations. The article also recommends viable management plans to refer to as contingency strategies for probable future challenges. Furthermore, this study attempts to fill a gap in the literature on start-up entrepreneurship in language and culture-related tourist attractions.

"Physics Curriculum Standards for Compulsory Education (2011 Edition)" requires that physics teaching in junior high schools should focus on the development of students' scientific abilities, including the development of scientific knowledge and skills, scientific methods and attitudes. In view of the problems existing in middle school physics teaching such as being out of touch with real life, lack of interest, and traditional indoctrination teaching, integrating STEAM education concepts into physics experiment courses can greatly improve the interest of physics teaching and put students first. , teachers as instructors and assistants to improve the existing problems in the current physics teaching. Therefore, how to reasonably apply the STEAM education concept to the physical experiment course is a question worth exploring. I take "the design and production of floating sinks" as an example. The general idea is to build the main line of classroom teaching: the smoothness of knowledge logic, the progress of students' cognitive laws, the smooth design of teaching activities, and how to learn buoyancy and explore objects. To better understand the floating and sinking of objects when floating and sinking, interspersed with the educational concept of STEAM.

The construction industry is responsible for over 40% of global energy consumption and one-third of global greenhouse gas emissions. Generally, 10%–20% of energy is consumed in the manufacturing and transportation stages of materials, construction, maintenance, and demolition. The way the construction industry to deal with these impacts is to intensify sustainable development through green building. The author uses the latest Green Building Certification Standard in Indonesia as the Green Building Guidelines under the Ministry of Public Works and People’s Housing (PUPR) Regulation No. 01/SE/M/2022, as a basis for evaluating existing office buildings or what is often referred to as green retrofit. Structural Equation Modeling-Partial Least Squares (SEM-PLS) is used by the authors to detail the factors influencing the application of green building by analyzing several variables related to the problem studied, which are used to build and test statistical models of causal models. From this study, it is concluded that the most influential factors in the implementation of green retrofitting on office buildings are energy savings, water efficiency, renewable energy use, the presence of green building socialization programs, cost planning, design planning, project feasibility studies, material cost, use of the latest technology applications, and price fluctuations. With the results of this research, there is expected to be shared awareness and concern about implementing green buildings and green offices as an initiative to present a more energy-efficient office environment, save operating costs, and provide comfort to customers.

This study aims at predicting the interrelationship between among Chat GPT with its six dimensions, tourist’s satisfaction and Chat GPT usage intention as perceived by tourist, and as well as to examine the moderating effect of traditional tour operator services on the relationships between all the variables. Data were collected from 624 tourists. The study hypotheses were tested and the direct and indirect effects between variables were examined using the PLS-SEM. The SEM results showed that Chat GPT’s six dimensions have a positive and significant direct impact on tourist’s satisfaction, and emphasis the moderating role of Traditional Tour Operator Services “TTOS” on the relationship between GPT’s six dimensions and “TS”, and on the relationship between ‘TS” and Chat GPT usage intention. These findings yield valuable insights for everyone interested in the use of IT in the tourism industry, and provide effective strategies for optimizing the use of technological applications by traditional tour operators.