Amyloidosis is a systemic disorder produced by the deposition of insoluble protein fibrils that fold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality than patients without cardiac involvement. The two most prevalent forms of amyloidosis associated with cardiac involvement are AL amyloidosis, due to the deposition of immunoglobulin light chains, and ATTR amyloidosis, due to the deposition of the transthyretin (TTR) protein in mutated or senile form. This article aims to review the different cardiac imaging modalities (echocardiography, cardiac magnetic resonance imaging, nuclear medicine and tomography) that allow to determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, we suggest a diagnostic algorithm to determine cardiac involvement in amyloidosis adapted to locally available diagnostic tools, with a practical and clinical approach.
Boron and tungsten carbides, B4C and WC, are hard materials widely used in modern technologies. Further improvement of their performance characteristics involves the development of new B4C and WC-based and/or related composites in a nanodispersed state. This article provides a review of available literature research on B-C-W systems, which would be useful in future studies in this direction.
The technological infrastructure is the basis for the successful implementation and operation of information systems in small and medium enterprises. The study aimed to demonstrate the impact of cybersecurity on entrepreneurship strategies in small and medium enterprises. Through technological infrastructure in Balqa Governorate. The study population consisted of small and medium enterprises in Balqa Governorate in Jordan. The study followed the descriptive analytical approach and relied on the questionnaire to collect data. The sample size was 360 individuals were randomly select. The Statistical Package for Social Sciences (SPSS) was use to analyze the data. The study reached a set of results, including that the management of small and medium enterprises is committed to continuous supervision and control of customer information. Dealing with reliable parties to ensure the confidentiality of information, following strict standards for disclosure and circulation of customer data and information based on legal texts. Maintaining the privacy of customers’ financial data, in addition to supporting the successes of individuals based on the personal efforts of employees, providing a suitable work environment for employees, sustaining excellence and achievement, and working to increase awareness among its employees of the importance of innovation and creativity in work. The study recommended that customer data confidentiality should be consider a top priority for small and medium enterprises. The data should be stored in more than one place at the same time, that project websites should follow a privacy policy, and that the customer’s identity should be verify before submitting his data and documents, by involving employees in small and medium enterprises in specialized courses and workshops to demonstrate the importance of data and information confidentiality.
Higher education (HE) consists of both conventional and non-conventional methods of learning. Open and Distance Learning (ODL) is a non-conventional system where teachers (often referred to as facilitators) are physically not present. The conduct of practical in engineering and science education using ODL remains a challenge due to inadequate technology and the dispersion of the students, which results in a graduate skills gap in ODL programs. There is a possibility of using a cloud computing set-up, as well as platforms for the creation of simulated virtual practical settings (virtual laboratories-VLs), which could be accessible by ODL engineering and science and education-based students notwithstanding their locations. This paper adds to existing knowledge on VLs and discusses these inadequacies in engineering and science education with emphasis on the enhancement of online and collaborative learning, as well as the possible laboratory (lab) requirements. In addition, the paper highlights contemporary trends and some issues in VLs and remote labs.
The well-being of society can be realized through meeting basic needs, one of which is providing public infrastructure. This study examines the role of Natural Resource Revenue Sharing Funds (DBH SDA) on government investment in infrastructure in 491 regencies/cities in Indonesia. The testing in this research uses panel data regression analysis. The results show that per capita DBH SDA in Indonesia during the study period of 2010–2012 has a significant and positive influence on government investment in infrastructure. The selection of this period is based on the consideration that a resources boom has occurred, where there is an increased global demand for natural resource commodities followed by an increase in commodity prices, thereby positively impacting revenue for countries or regions abundant in natural resources. Despite DBH SDA having a significant and positive influence, regional spending on infrastructure tends to be more influenced by central government transfers such as General Allocation Fund (DAU), Special Allocation Fund (DAK), and Local Own-source Revenue (PAD). It was found that government investment in infrastructure tends to be influenced by transfer funds, indicating that the role of the central government remains significant in determining the infrastructure expenditure of regencies/cities in Indonesia.
Climate change is an important factor that must be considered by designers of large infrastructure projects, with its effects anticipated throughout the infrastructure’s useful life. This paper discusses how engineers can address climate change adaptation in design holistically and sustainably. It offers a framework for adaptation in engineering design, focusing on risk evaluation over the entire life cycle. This approach avoids the extremes of inaction and designing for worst-case impacts that may not occur for several decades. The research reviews case studies and best practices from different parts of the world to demonstrate effective design solutions and adjustment measures that contribute to the sustainability and performance of infrastructure. The study highlights the need for interdisciplinary cooperation, sophisticated modeling approaches, and policy interventions for developing robust infrastructure systems.
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