This study focused on the formulation and characterization of silver nanoparticles (AgNP) functionalized with d-limonene. The nanoparticles were functionalized by phase inversion and the synthesis of the nanoparticles was performed in situ; particle size was determined by laser diffraction, zeta potential and optical colloidal stability using Multiscan 20 for a period of 24 hours at 37 °C; the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the formulated material on Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Klebsiella oxytoca ATCC 700324, Enterococcus casseliflavus ATCC 700327, Escherichia coli BLEE, carbapenem-resistant Pseudomona aeruginosa were determined. The nanoparticles showed colloidal stability at a d-limonene concentration of 3.93%, silver ions at 1.61 × 10−3%, non-ionic adjuvant at 24% and ascorbic acid at 5.88%; citric acid/citrate (1:1) 0.48M for a pH of 4.5 was used as a buffer system. The formulation was classified as a polydisperse system (PD = 0.0851), with a zeta potential of −11.6 mV and average particle size of 81.5 ± 0.9 nm. A particle migration velocity of −0.199 ± 0.006 mm∙h−1, a constant transmission profile and backscattering profile with variations of 10% were evidenced, which represents a stable formulation. The nanoparticles presented an MIC and an MBC of 28 μg∙mL−1 (5.6 × 10−2% d-limonene and 4.7 × 10−5% AgNP) against all tested bacteria.
In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.
Global navigation satellite system and its application fields are constantly expanding and deepening. This paper mainly introduces the current situation of global satellite navigation system and its application technology, development trend and application prospect. At the same time, this paper makes a comprehensive comparison of these navigation systems, analyzes the opportunities and challenges faced by China’s BeiDou satellite navigation system in the global context, and puts forward some suggestions for future work.
In order to promote the application of noise map in high-speed railway noise management, the high-speed railway noise map drawing technology based on the combination of noise prediction model and geographic information system (GIS) is studied. Firstly, according to the distribution characteristics of noise sources and line structure characteristics of high-speed railway, the prediction model of multi equivalent sound sources and the calculation method of sound barrier insertion loss of high-speed railway are optimized; secondly, a three-dimensional geographic information model of a high-speed railway is built in GIS software, and the railway noise prediction technology based on the model is developed again; then, the noise of discrete nodes is calculated, and the continuous noise distribution map is drawn by spatial interpolation. The research results show that the comparison error between the noise map of a high-speed railway drawn by this technology and the measured results is less than 1 dB (A), which verifies the accuracy and practicality of the high-speed railway noise map, and can be used as a reference for the railway noise management department to formulate noise control countermeasures.
Ecological environment damage events will destroy or damage the balance between animal and plant habitats and ecosystems, and even pose a threat to China’s ecological security. However, at present, there are some problems in the identification and evaluation of forest ecosystem damage, such as imperfect evaluation system, insufficient quantitative evaluation methods, imperfect damage compensation management system, and lack of analysis of the overall damage of the interaction between human activities and forest ecosystem. Based on the damaged object, the system involves a total of four first-class indicators, including physical damage, mental damage, economic forest fruit loss, forest by-products loss, processing and manufacturing loss, forest tourism loss, scientific research literature and history loss, soil conservation loss, water conservation loss, wind prevention and sand fixation loss, carbon fixation and oxygen release loss, atmospheric purification loss. There are 14 secondary indicators of emergency treatment fee and investigation and evaluation fee, as well as 22 tertiary indicators, and the value quantification method of each indicator is clarified by using market value method, alternative cost method, shadow engineering method, recovery cost method and other methods. The article also discusses the management system of forest ecosystem damage from the two aspects of forestry technology department and judicial administration department. The purpose is to provide reference for the quantification and standardization of forest ecosystem damage assessment technology and the improvement of management system.
Based on the collective forest with common use rights, the social-ecological system analysis framework and autonomous governance theory proposed by Elinor Ostrom are introduced in the forest eco-economic system to analyze the interaction logic among the first-level subsystems and the secondary variables of the forest eco-economic system and the variables related to the autonomous governance of the system to explore the synergistic mechanisms affecting the forest eco-economic system. The results show that: in the case of information asymmetry, collective actions of governmental and non-governmental organizations will aggravate the dilemma of forest eco-economic synergistic development; actors extract forest resource units from the forest resource system to achieve economic benefits; and renewable resources of forest ecosystems can be sustained in the long term when the average extraction rate of humans from forest ecosystems does not exceed the average replenishment rate.
Copyright © by EnPress Publisher. All rights reserved.