The rising trend of tourists selecting agrotourism as a tourist destination has become an intriguing study issue. Seremban is a well-known tourist attraction that is popular among visitors. As a result, Seremban has been selected as the study site. However, river pollution may have an influence on Seremban’s natural environment and agrotourism potential. Furthermore, inadequate infrastructure, such as unauthorized parking, exacerbated the inhabitants’ problems. A growing number of young people leave Seremban to pursue employment or further education in other cities, with no desire to work as farmers. The labor scarcity has also made it difficult for farmers to grow their farms. Consequently, the study aims to examine how factors such as the natural environment, tourist infrastructure, perceived social advantages, and perceived barriers influence the attitudes of Seremban residents towards agrotourism, with a focus on its potential for driving economic growth. This study adopts quantitative research methods, employing descriptive and causal research designs. Primary data collection is conducted through questionnaires, supplemented by secondary data. Non-probability quota sampling is utilized due to the absence of a specific sampling frame, with a sample size of 385 respondents determined using G*Power software. Constructs are developed based on previous research, and the questionnaire comprises Likert-scale items to gauge attitudes and perceptions. A pilot study assesses the instrument’s reliability. Data analysis is performed using SPSS software, encompassing multiple linear regression and Pearson correlation analyses in addition to descriptive statistics. The findings provide valuable insights into the factors driving residents’ perceptions of agrotourism in Seremban, emphasizing the importance of the natural environment, tourism infrastructure, perceived social benefits, and perceived barriers in shaping attitudes. Additionally, the study highlights the resilience of residents’ positive attitudes toward agrotourism, despite potential challenges and barriers identified. Overall, these results offer implications for policymakers and stakeholders involved in tourism development in the region.

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.

A systemic and synthetic review of the anatomy of the temporomandibular joint in magnetic resonance imaging was developed for its evaluation. The temporomandibular joint is an anatomical structure composed of bones, muscles, ligaments and an articular disc that allows important physiological movements, such as mandibular opening, closing, protrusion, retrusion and lateralization. Magnetic resonance imaging is an imaging technique that does not use ionizing radiation and is more specific for the evaluation and interpretation of soft tissues, due to its high resolution, so it has an important role in the diagnosis of various maxillofacial pathologies, which is why the dentist should have knowledge of the structures and functions of the temporomandibular joint through magnetic resonance imaging. The review demonstrates the importance of magnetic resonance imaging in the study of the anatomy of the temporomandibular joint, in addition to mentioning the advantages provided by this imaging technique such as its good detail of the soft tissues in its different sequences and the non-use of ionizing radiation to obtain its images.