This paper presents a coupling of the Monte Carlo method with computational fluid dynamics (CFD) to analyze the flow channel design of an irradiated target through numerical simulations. A novel series flow channel configuration is proposed, which effectively facilitates the removal of heat generated by high-power irradiation from the target without necessitating an increase in the cooling water flow rate. The research assesses the performance of both parallel and serial cooling channels within the target, revealing that, when subjected to equivalent cooling water flow rates, the maximum temperature observed in the target employing the serial channel configuration is lower. This reduction in temperature is ascribed to the accelerated flow of cooling water within the serial channel, which subsequently elevates both the Reynolds number and the Nusselt number, leading to enhanced heat transfer efficiency. Furthermore, the maximum temperature is observed to occur further downstream, thereby circumventing areas of peak heat generation. This phenomenon arises because the cooling water traverses the target plates with the highest internal heat generation at a lower temperature when the flow channels are arranged in series, optimizing the cooling effect on these targets. However, it is crucial to note that the pressure loss associated with the serial structure is two orders of magnitude greater than that of the parallel structure, necessitating increased pump power and imposing stricter requirements on the target container and cooling water pipeline. These findings can serve as a reference for the design of the cooling channels in the target station system, particularly in light of the anticipated increase in beam power during the second phase of the China Spallation Neutron Source (CSNS Ⅱ).

Bael or Aegle marmelos Corrêa is considered a sacred tree by Hindus and is offered to Lord Shiva while worshipping. It grows in the Indian subcontinent and Southeast Asia and is called by various names in different regions. Bael has been used as a traditional medicine in India and other Southeast Asian countries to treat various ailments, including diarrhea, chronic dysentery, constipation, gonorrhea, catarrh, diabetes, deafness, inflammations, ulcerated intestinal mucosa, intermittent fever, melancholia, heart palpitation, and also to control fertility. The ethnomedicinal properties of Bael are owing to its ability to synthesize alkaloids, cardiac glycosides, anthocyanins, flavonoids, steroids, saponins, terpenoids, tannins, lignins, quinones, coumarins, proteins, carbohydrates, amino acids, reducing sugars, fats, and oils. The aegeline, auroptene, umbelliferone, psoralene, marmin, imperatorin, xylorhamnoarabinogalactan I pectic polysaccharide and skimmianine are synthesized by different parts of Bael, and they have shown antibacterial, anti-inflammatory, analgesic, anti-allergic, anthelmintic, antidiabetic, anticancer, cardioprotective and neuroprotective activities in various experimental models. The present review has been written consulting various publications, and different websites including Google Scholar, Pubmed, ScienceDirect, and Google.

Nanotechnology is a subject that studies, processes, and applies various functional materials, equipment, and systems, and controls substances on a nanoscale. Nanomedicine refers to its application in diagnosing, treating, preventing, and monitoring various diseases. Drugs administered through eye drops must travel a long distance to avoid various eye barriers reaching the posterior segment of the eye, to achieve the lowest drug level. This review focuses on nanotechnology-based eye disease treatment systems and highlights the obstacles affecting the drug management of eyes and nano-systems for the treatment of eye diseases. This paper summarizes the development prospect of nanotechnology and the challenges it faces in the treatment and diagnosis of ophthalmic diseases, to provide information and new ideas for the implementation of treatment and the development of a refractory eye disease management system.

[Objective]In order to explore the sustainable food security level in the Yangtze River Economic Belt, ensure food security and sustainable development of agricultural modernization, it is necessary to establish a scientific food security evaluation system to safeguard local food security.[Methods]This paper takes the food system of the Yangtze River Economic Belt in China as the research object, based on the food security research results at home and abroad, based on sustainable development thinking, combined with a new perspective of dynamic equilibrium research: Beginning with food normalcy, a comprehensive analysis of food production, food economy, social development, ecological security, and technical support for sustainable development is presented using the entropy-weighted TOPSIS model to build a food security evaluation system for sustainable development. [Conclusion]After systematic analysis, it is concluded that (1) the average value of food security score of the Yangtze River Economic Belt from 2008 to 2021 is 0.429, and the overall food in the Yangtze River Economic Belt is in general security level (0.400 ≤ Q1 ≤ 0.600), and the overall situation of food security is not optimistic, (2) from the segmentation of the Yangtze River Economic Belt, the high and low level of food security are divided into sections: midstream > downstream > upstream, and each province and city is slowly rising to different degrees. In this way, we propose general countermeasures to ensure local food security from the perspective of sustainable development.

This study examines the spatial distribution of consumption competitiveness and carrying capacity across regions, exploring their interrelationship and implications for sustainable regional development. An evaluation index system is constructed for both consumption competitiveness and carrying capacity using a range of economic, social, and environmental indicators. We apply this framework to regional data in China and analyze the resultant spatial patterns. The findings reveal significant regional disparities: areas with strong consumption competitiveness are often concentrated in economically developed regions, while high carrying capacity is notable in less populated or resource-rich areas. Notably, a mismatch emerges in some regions—high consumer demand is not always supported by adequate carrying capacity, and vice versa. These disparities highlight potential sustainability challenges and opportunities. In the discussion, we address reasons behind the spatial mismatch and propose policy implications to better align consumer market growth with regional resource and environmental capacity. The paper concludes that integrating consumption-driven growth strategies with carrying capacity considerations is essential for balanced and sustainable regional development.

Dredging and reclamation operations are pivotal aspects of coastal engineering and land development. Within these tasks lie potential hazards for personnel operating dredging machinery and working within reclamation zones. Due to the specialized nature of the work environment, which deviates from conventional workplace settings, the risk of workplace accidents is significantly heightened. The aim of this study is to conduct a comprehensive risk analysis of the safety aspects related to dredging and reclamation activities, with the goal of enhancing safety and minimizing the frequency and severity of potential dangers. This research comprises a thorough risk analysis, integrating meticulous hazard identification from sample projects and literature reviews. It involves risk assessment by gathering insights from experts with direct working experience and aims to assess potential risks. The study focuses on defining effective risk management strategies, exemplified through a case study of a nearshore construction project in Thailand. The study identified numerous high and very high-risk factors in the assessment and analysis of occupational safety in dredging and reclamation work. Consequently, a targeted response was implemented to control and mitigate these risks to an acceptable level. The outcome of this study will provide a significant contribution to the advancement of guidelines and best practices for improving the safety of dredging and reclamation operations.