Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.
The suspicion of mediastinal alterations, always includes in its initial study, the chest radiography. The identification of mediastinal alterations in the X-ray is a priority. The knowledge of the mediastinal references and the identification of their alterations allows the suspicion of a pathology specific to each of the mediastinal spaces. When the semiology of mediastinal lesions, their location and the three most frequent pathologies are taken into account, the possibility of having an etiological diagnosis increases[1]. This is a review article based on a detailed literature search, in which radiological mediastinal references are studied, with emphasis on the epidemiological data of each one of them.
In order to promote the application of noise map in high-speed railway noise management, the high-speed railway noise map drawing technology based on the combination of noise prediction model and geographic information system (GIS) is studied. Firstly, according to the distribution characteristics of noise sources and line structure characteristics of high-speed railway, the prediction model of multi equivalent sound sources and the calculation method of sound barrier insertion loss of high-speed railway are optimized; secondly, a three-dimensional geographic information model of a high-speed railway is built in GIS software, and the railway noise prediction technology based on the model is developed again; then, the noise of discrete nodes is calculated, and the continuous noise distribution map is drawn by spatial interpolation. The research results show that the comparison error between the noise map of a high-speed railway drawn by this technology and the measured results is less than 1 dB (A), which verifies the accuracy and practicality of the high-speed railway noise map, and can be used as a reference for the railway noise management department to formulate noise control countermeasures.
Based on the collective forest with common use rights, the social-ecological system analysis framework and autonomous governance theory proposed by Elinor Ostrom are introduced in the forest eco-economic system to analyze the interaction logic among the first-level subsystems and the secondary variables of the forest eco-economic system and the variables related to the autonomous governance of the system to explore the synergistic mechanisms affecting the forest eco-economic system. The results show that: in the case of information asymmetry, collective actions of governmental and non-governmental organizations will aggravate the dilemma of forest eco-economic synergistic development; actors extract forest resource units from the forest resource system to achieve economic benefits; and renewable resources of forest ecosystems can be sustained in the long term when the average extraction rate of humans from forest ecosystems does not exceed the average replenishment rate.
Over several centuries, the native vegetation of the flat part of the Bogotá Savanna has been almost completely replaced by crops, pastures and urbanization. The last remnant of this vegetation is a small forest (10 hm2), located at Hacienda Las Mercedes on the northern edge of the city of Bogotá. The reduced size and isolation of the forest, aggravated by the uncontrolled growth of invasive vegetation (lianas and wild blackberry) has resulted in the loss of many species. However, in recent years the forest has been subject to rehabilitation actions and currently the area is immersed in a reserve where more extensive restoration programs are planned. In order to evaluate changes in the bird community to estimate the effects of restoration actions, the avifauna present in 2001–2002 and in 2014 was recorded by visual and auditory records at fixed points in the forest. Twenty-seven forest species were found in the first census and 30 in the second, and the relative abundances of at least a third of them also increased over the 13 years, indicating a positive result in the recovery of the forest. The results highlight the recovery capacity of the degraded ecosystems and the importance of continuing with restoration actions in the reserve area.
Adsorption is a widely used method for the treatment of dissolved contaminants. Various agro-industrial wastes have been explored as potential adsorbents, showing high efficiency in dye removal. Each adsorbate-adsorbent pair needs kinetic, and equilibrium models to scale up this process. In this work, the equilibrium, kinetics and thermodynamics of the corn Tuza-Red 40 system were evaluated under batch system at ph = 2.0 at temperatures of 25, 40, and 55 °C. The Langmuir, Freundlich and Temkin models were selected for the isotherm representation, while the Lagergren, Ho, and Elovich equations for the kinetics of the process. The Freundlich model presented the best fit to the isotherms, the adsorption kinetics was best described by the Ho equation, and the values for Gibbs free energy and entropy indicated the spontaneity and feasibility of the process.
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