The cost of diagnostic errors has been high in the developed world economics according to a number of recent studies and continues to rise. Up till now, a common process of performing image diagnostics for a growing number of conditions has been examination by a single human specialist (i.e., single-channel recognition and classification decision system). Such a system has natural limitations of unmitigated error that can be detected only much later in the treatment cycle, as well as resource intensity and poor ability to scale to the rising demand. At the same time Machine Intelligence (ML, AI) systems, specifically those including deep neural network and large visual domain models have made significant progress in the field of general image recognition, in many instances achieving the level of an average human and in a growing number of cases, a human specialist in the effectiveness of image recognition tasks. The objectives of the AI in Medicine (AIM) program were set to leverage the opportunities and advantages of the rapidly evolving Artificial Intelligence technology to achieve real and measurable gains in public healthcare, in quality, access, public confidence and cost efficiency. The proposal for a collaborative AI-human image diagnostics system falls directly into the scope of this program.
Objective: To determine the presence of bacteria by means of microbiological analysis on the surfaces contacted by the operator during the taking and processing of intraoral radiographs at different times of the day in the Oral Radiology Service of the UPCH. Materials and methods: Nine surfaces of the oral radiology service were sampled. The samples were taken at two times by the same investigator; at the beginning and the end of the activities in the service, the surfaces were swabbed with Trypticase Soy Broth (TSB). The samples were inoculated and incubated in three culture media (Plate Count Agar, Lamb’s Blood Agar and Cetrimide Agar). Then the respective Colony Forming Unit (CFU) count was performed and Gram staining was also performed. Results: A high concentration of bacteria (4180 CFU/mL) and fungi was found in the oral radiology service. Gram-positive cocci were the most frequently found microorganisms and gram-negative bacilli were less frequently found. Conclusions: There is a high contamination of bacteria in the oral radiology service. When the activities are completed, the number of bacteria decreases, but the variety of bacteria increases.
In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.
In order to promote the application of noise map in high-speed railway noise management, the high-speed railway noise map drawing technology based on the combination of noise prediction model and geographic information system (GIS) is studied. Firstly, according to the distribution characteristics of noise sources and line structure characteristics of high-speed railway, the prediction model of multi equivalent sound sources and the calculation method of sound barrier insertion loss of high-speed railway are optimized; secondly, a three-dimensional geographic information model of a high-speed railway is built in GIS software, and the railway noise prediction technology based on the model is developed again; then, the noise of discrete nodes is calculated, and the continuous noise distribution map is drawn by spatial interpolation. The research results show that the comparison error between the noise map of a high-speed railway drawn by this technology and the measured results is less than 1 dB (A), which verifies the accuracy and practicality of the high-speed railway noise map, and can be used as a reference for the railway noise management department to formulate noise control countermeasures.
There is a large literature on public-private-partnership, covering many different areas and aspects. This article deals with a specific but important aspect: the decision-making mechanisms to choose the management of PPP enterprises. In this sector, a suitable choice of managers is of particular importance because the persons chosen must balance the public and private interests. This is often difficult to achieve. Two new procedures are discussed, “Directed Random Choice” and “Rotating CEOs”. In each case, the advantages and disadvantages of the procedure of choosing the managers of PPP enterprises are discussed and evaluated. It is concluded that the two novel mechanisms should be seriously considered when choosing the managers of PPP enterprises.
There are several methods in the literature to find the fuzzy optimal solution of fully fuzzy linear programming (FFLP) problems. However, in all these methods, it is assumed that the product of two trapezoidal (triangular) fuzzy numbers will also be a trapezoidal (triangular) fuzzy number. Fan et al. (“Generalized fuzzy linear programming for decision making under uncertainty: Feasibility of fuzzy solutions and solving approach”, Information Sciences, Vol. 241, pp. 12–27, 2013) proposed a method for finding the fuzzy optimal solution of FFLP problems without considering this assumption. In this paper, it is shown that the method proposed by Fan et al. (2013) suffer from errors and to overcome these errors, a new method (named as Mehar method) is proposed for solving FFLP problems by modifying the method proposed by Fan et al. (2013) . To illustrate the proposed method, some numerical problems are solved.
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