The wave effect and the shyness phenomenon in Alnus acuminata (Kunth) are crown parameters rarely studied, but important in the quality of the wood of standing trees, therefore, a morphometric modeling of the crowns of Alnus acuminata in homogeneous forests in the Sierra Norte de Puebla was carried out. In 20 rectangular sites of 1,000 m², the following were evaluated: total height (TA), normal diameter (ND), crown diameter (CD) and crown cover (CC). The Kruskal Wallis test was applied to data that did not meet the assumption of normality; for those that did, analysis of variance (ANOVA) was used, with Tukey mean comparison tests (α ≤ 0.05). The forest value index was 14.99, so its two-dimensional structure is normal based on DN, AT and CC. Its average slenderness index was 93.52, which makes the tree not very stable to mechanical damage. The life-space index was 38.92, which is high indicating that trees with low intraspecific competition developed better. At the canopy level, a pattern following an upward, oscillatory and constant wave effect was observed in groups of 10 trees. The shyness phenomenon showed an average crack opening of 27.39 cm between canopies, so this phenomenon is well defined for the species. It is concluded that in the crowns of Alnus acuminata, the wave effect is observed as a consequence of inequality in the acquisition of resources, and one way to minimize this inequality is through the phenomenon of botanical shyness.

Objective: To describe magnetic resonance imaging (MRI) findings of the brain in patients younger than 65 years who were studied by transcranial Doppler (TCD) with microbubble contrast, with a history of cryptogenic cerebrovascular accident (CVA) and suspected patent foramen ovale (PFO).

Materials and methods: This retrospective cross-sectional study included patients of both sexes, younger than 65 years of age.

Results: Our sample (n = 47.47% male and 53% female, mean age is 42 years) presented high-intensity transient signals (HITS) positive in 61.7% and HITS-negative in 38.3%. In HITS-positive patients, lesions at the level of the subcortical U-brains, single or multiple with bilaterally symmetrical distribution, predominated. In patients with moderate HITS, lesions in the vascular territory of the posterior circulation predominated.

Conclusion: In patients younger than 65 years with cryptogenic stroke and subcortical, single or multiple U-shaped lesions with bilateral and symmetrical distribution, a PFO should be considered as a possible cause of these lesions.

The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.