The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.
This paper aims to explore the practice and effect of integrating ideological and politics in higher vocational mathematics education. Through the review of relevant literature and the analysis of practical cases, this study analyzes the necessity and feasibility of integrating ideological and political education into higher vocational mathematics teaching, as well as the promoting effect of students' ideological and political education. At the same time, it also discusses how to effectively combine the curriculum thinking and politics with higher vocational mathematics teaching, as well as the strategies and methods to achieve positive results, in order to provide some reference for the majority of higher vocational mathematics teachers.
Since January 1, 2016, the national population and family having two child policy comprehensively, the whole country gradually ushered in the second the arrival of the age of the child, in terms of my garden at this stage, the second child children have been accounted for dominated nearly 1/5 of the total number of children, for big kindergarten children, all of a sudden more than a new member in the home, he (she) to share the love of your family, Let the orderly life become no longer regular, their psychological more or less confused and anxious, this paper will from the perspective of kindergarten teachers in our kindergarten in the "two-child era" background to focus on the health of children's psychological practice and exploration.
There are a number of issues that can influence elderly life satisfaction, which can mirror their welfare. This study aims to explore the differences in elderly parents’ life satisfaction across socioeconomic characteristics and investigates how the traits of both children and parents associate with elderly parents’ life satisfaction in Thailand. This study uses individual data obtained from Thailand’s National Statistical Organization covering 2008–2015, 2018 and 2020, with a total sample size of 28,494. To investigate the association between children’s and parents’ characteristics, particularly formal education and parental life satisfaction, this study uses ordered logistic regression for the analysis. Our results show that male parents are more likely to have higher life satisfaction than their female counterparts. Parents who are employed, holding a bachelor’s degree, and living with female children are more satisfied with their life. Statistically, children’s formal education demonstrates its importance for their elderly parents’ life satisfaction. This documents the vital role of schooling in improving parental life satisfaction. Moreover, facing the challenge of entering an aging society, government agencies must take a proactive stance on creating jobs suitable for the elderly or retirees to maintain their sense of independence. The evidence of intergenerational mobility reaffirms the importance of children’s education along with their caring ability, which should be strengthened.
In the context of big data, the teaching of financial accounting for vocational undergraduate students needs to be continuously optimized and innovated. This article provides a brief analysis of the current situation of financial accounting teaching for vocational undergraduate students. It also analyzes the phenomena of outdated teaching concepts, outdated teaching content, and unreasonable teaching objectives in the current teaching of financial accounting for vocational undergraduate students. It proposes the idea of innovating teaching concepts in current teaching work, clarifying teaching objectives, integrating flipped classroom reform teaching mode, and introducing project-based teaching method to improve teaching efficiency, so as to achieve more efficient teaching guidance for students.
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