Cancer is the 3rd leading cause of death globally, and the countries with low-to-middle income account for most cancer cases. The current diagnostic tools, including imaging, molecular detection, and immune histochemistry (IHC), have intrinsic limitations, such as poor accuracy. However, researchers have been working to improve anti-cancer treatment using different drug delivery systems (DDS) to target tumor cells more precisely. Current advances, however, are enough to meet the growing call for more efficient drug delivery systems, but the adverse effects of these systems are a major problem. Nanorobots are typically controlled devices made up of nanometric component assemblies that can interact with and even diffuse the cellular membrane due to their small size, offering a direct channel to the cellular level. The nanorobots improve treatment efficiency by performing advanced biomedical therapies using minimally invasive operations. Chemotherapy’s harsh side effects and untargeted drug distribution necessitate new cancer treatment trials. The nanorobots are currently designed to recognize 12 different types of cancer cells. Nanorobots are an emerging field of nanotechnology with nanoscale dimensions and are predictable to work at an atomic, molecular, and cellular level. Nanorobots to date are under the line of investigation, but some primary molecular models of these medically programmable machines have been tested. This review on nanorobots presents the various aspects allied, i.e., introduction, history, ideal characteristics, approaches in nanorobots, basis for the development, tool kit recognition and retrieval from the body, and application considering diagnosis and treatment.

Since my country entered the era of Internet economy, the scale of the software industry is gradually expanding, and programming language, as an important tool and idea for software development, is a necessary skill for every development practitioner. Among them, C language, as the basic language of computer software programming, is also an important basic course for cultivating students’ computer application ability in science and engineering majors in colleges and universities. This paper mainly studies the teaching reform of C language programming courses and proposes corresponding optimization measures, so as to lay a solid foundation for the continuous improvement of students’ learning quality of C language courses and the continuous strengthening of programming ability.

The present study assessed the potential of sediment loading in Beteni, Lauruk, Andheri, and Harpan sub-watersheds of Phewa Lake and estimated the sediment yield in the year 2020. Morphometry, land use/land cover, geology, climate, and human and development factors of the sub-watersheds were studied to assess the potential of sediment loading in the sub-watersheds. SRTM DEM was used for the computation of morphometric parameters and land use/land cover maps were prepared by using Landsat imagery. Geology, rainfall data, census data, and road maps were collected from various secondary sources. The sediment yields of the four sub-watersheds in the year 2020 were estimated by measuring the sediment volume deposited in the sediment retention ponds at the outlet of each sub-watershed. Results indicated that Beteni had the highest potential for sediment loading, while Harpan had the lowest. Likewise, the sediment yields for Beteni, Lauruk, Andheri, and Harpan sub-watersheds in 2020 were estimated at 1,420.67 m³/km²/year, 2,280.14 m³/km²/year, 1,666.77 m³/km²/year, and 766.42 m³/km²/year, respectively. To reduce sedimentation in Phewa Lake, it is recommended to regularly maintain siltation dams and construct check dams along the drainage slopes, alongside other soil conservation measures and appropriate land use practices in the upstream areas of the sub-watersheds.

Currently, important efforts are being made to improve governability and governance by combining the monopoly of state decisions with the collaboration of diverse actors in public practice. Based on the above, the purpose of this article is to analyze the evolution of conceptual approaches to both terms over the last 23 years, examining scientific production by author authors, journals, and countries. The methodology was based on a bibliometric analysis: First, the WoS and Scopus databases were searched. Subsequently, scientometric techniques and the Science Tree methodology were used to identify patterns, structures, and trends, to understand the progress and behavior of scientific production, and to measure the quantity and quality of research that has addressed these issues from different perspectives. This study examined governability and governance publications and their annual citations to assess their impact and analyzed the total output of both datasets to identify similarities and differences in governability and governance research. The findings reveal that the number of publications and citations in this field is increasing, with the United States being the most academically influential country and the journal Marine Policy being the most prominent in ranking. These data provide key information for decision-makers, researchers, and academics for future debate and discussion toward operationalizing the concepts at the practical level of action, management, and the functioning of government structures.

Zero-valent iron is a moderately reducing reagent that is both non-toxic and affordable. In the present work, iron nanoparticles were synthesized using bitter guard leaf extract (Momordica charantia L.) (BGL-Fe NP). Using leaf samples from bitter protectant extract, iron nanoparticles were synthesized with secondary metabolites such as flavonoids and polyphenols acting as capping and reducing agents. Polyphenols reduce Fe²⁺/Fe³⁺ to nanovalent iron or iron nanoparticles. Iron nanoparticles were synthesized by reducing iron chloride as a precursor with bitter protective leaf extract in an alkaline environment. The obtained BGL-Fe NPs were calcined for 4 h at various temperatures of 400 °C, 500 °C, and 600 °C. The obtained samples were coded as BGL-Fe NPs-4, BGL-Fe NPs-5, and BGL-Fe NPs-6, respectively. The synthesized BGL-Fe NPs were systematically characterized by XRD, SEM, FTIR, UV-Vis and TG-DTA analysis. The obtained BGL-Fe NPs were then used as an adsorbent to remove the aqueous solution of basic methylene blue (MB) dye. MB concentration was monitored using UV-Vis spectroscopy.

The work is devoted to the numerical solution of the initial boundary value problem for the heat equation with a fractional Riesz derivative. Explicit and implicit difference schemes are constructed that approximate the boundary value problem for the heat equation with a fractional Riesz derivative with respect to the coordinate. In the case of an explicit difference scheme, a condition is obtained for the time step at which the difference scheme converges. For an implicit difference scheme, a theorem on unconditional convergence is proved. An example of a numerical calculation using an implicit difference scheme is given. It has been established that when passing to a fractional derivative, the process of heat propagation slows down.