In the current context of information technology development, many vocational colleges are reforming and developing their education majors in the direction of information technology. Now that we have entered the era of informatization, the direction of reform and innovation in the education industry can be considered to use the development methods of informatization to improve the comprehensive efficiency of teaching. In the context of informatization, the teaching of pharmacy majors in vocational colleges needs to seize the development advantages of informatization, reform classroom teaching methods, and improve teaching efficiency. This article mainly discusses how to integrate the teaching reform of pharmaceutical majors in vocational colleges with the development trend of informatization, achieve better reform and development efficiency, and cultivate pharmaceutical professionals.