Lifelong learning is the core content of university education work in the new period, and it is also the basic task of education work in colleges and universities. The second classroom is a kind of organized and planned educational and practical activities aiming at cultivating students' extracurricular ability and comprehensive quality. In the context of the new era, emphasizing and strengthening the construction of the second classroom in colleges and universities is an inevitable requirement for improving the quality of ideological and political education in colleges and universities. At present, there are still some problems in the moral education of the second classroom in colleges and universities in China. In order to enhance the effect of moral education in the second classroom of colleges and universities in the context of the new era, it is necessary to make a clear target positioning of the moral education of the second classroom, improve the process between the second classroom and the first classroom, and establish a three-dimensional system of moral education in the second classroom, so as to enhance its infectious and persuasive power.