The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.

Simulation training in dental medical eduaction is a modern high-tech approach in providing quality higher education. Simulation training immerses students in realistic scenarios, allowing them to develop both technical and non-technical skills essential for effective patient care. This study highlights key contemporary issues in high-tech simulation training for dental education and consolidates its rationale and benefits. We searched the databases PubMed, Scopus, Web of Science, and ResearchGate. This review includes 36 articles published in English, Russian, and Ukrainian from 2020 to 2024. Non-peer-reviewed papers or those not published in indexed journals were not considered. Simulation training was found to impact integration of theory and practice, training a wide range of psychomotor skills, development of complex clinical competences, cultivating confidence, empathy and patient-oriented care, neuroplasticity of the brain and the cognitive load. Pedagogical benefits and the place of simulation training in the curriculum were also discussed.

Technological advancements in genetic research are crucial for nations aiming to uplift their population’s quality of life and ensure a sustainable economy. Genomic information and biotechnology can enhance healthcare quality, outcomes, and affordability. The “P4 medicine approach”—predictive, preventive, personalized, and participatory—aligns with objectives like promoting long-term well-being, optimizing resources, and reducing environmental impacts, all vital for sustainable healthcare. This paper highlights the importance of adopting the P4 approach extensively. It emphasizes the need to enhance healthcare operations in real-time and integrate cutting-edge genomic technologies. Eco-friendly designs can significantly reduce the environmental impact of healthcare. Additionally, addressing health disparities is crucial for successful healthcare reforms.

This article explores ethnomedicine or traditional medication written in palm-leaf manuscripts in Lombok, West Nusa Tenggara. Most of the manuscripts in Lombok are written on palm leaf or lontar. One genre of palm-leaf manuscripts is USADA or traditional medication. These USADA manuscripts, serving as guides for traditional healers (dukun and balian), contain valuable information on diseases, treatments, herbal remedies, and incantations. The study reveals that ethnomedicine remains a relevant and respected practice in Lombok, often considered on par with modern medicine. Many residents rely on traditional healers for healthcare, particularly for minor illnesses. The research also highlights the living nature of the manuscript tradition, with continued recitation, copying, and teaching of these texts to younger generations. However, challenges persist in preserving these manuscripts and promoting wider appreciation for this unique cultural heritage.

5G technology is transforming healthcare by enhancing precision, efficiency, and connectivity in diagnostics, treatments, and remote monitoring. Its integration with AI and IoT is set to revolutionize healthcare standards. This study aims to establish the state of the art in research on 5G technology and its impact on healthcare innovation. A systematic review of 79 papers from digital libraries such as IEEE Xplore, Scopus, Springer, ScienceDirect, and ResearchGate was conducted, covering publications from 2018 to 2024. Among the reviewed papers, China and India emerge as leaders in 5G health-related publications. Scopus, Springer Link, and IEEE Xplore house the majority of first-quartile (Q1) papers, whereas Science Direct and other sources show a higher proportion in the second quartile (Q2) and lower rankings. The predominance of Q1 papers in Scopus, Springer Link, and IEEE Xplore underscores these platforms’ influence and recognition, reflecting significant advancements in both practice and theory, and highlighting the expanding application of 5G technology in healthcare.

Hospital performance possesses strategic significance in achieving an essential completive advantage for the public hospitals. This study aimed to examine the relationship between patient safety culture (PSC) and the performance of traditional Chinese medicine (TCM) public hospitals in Sichuan, China. To address the research purpose, this study analyses the hospital performance and Patient safety culture in traditional Chinese medicine public hospital in China. We examine the propose model by analyzing cross-sectional survey data from 194 clinical directors at 194 public traditional Chinese medicine hospitals using the Partial least squares structural equation model in Smart PLS 4.0. This study provides predictive evidence that PSC in unit management and management support can lead to better patient safety outcomes. The results revealed patient safety outcomes significantly and positively effects of patient safety related to unit management and management support on overall hospital performance (p-value: 0.000–0.003).