In 1859, the French invasion of Gia Dinh marked the beginning of their acquisition of Cochinchina. Shortly after their arrival, France brought printers on their ships, along with firearms and artillery. The printers were intended to quickly disseminate the policies of the invading army to the inhabitants of the occupied territory. At the end of 1861, the inaugural official newspaper in Cochinchina, ‘Le Bulletin officiel de l’expédition française de la Cochinchine’, had been published. The Royal Printing House (l’Imprimerie Impériale), the first printing facility in Cochinchina, was also established at the end of 1861 to accommodate printing tasks, particularly the production of gazettes. In 1873, various private printing houses emerged in Saigon-Cho Lon. Printing and publishing efforts gradually assimilated into the social fabric of Cochinchina after serving as a tool of the invaders. They transformed into political and cultural institutions within colonial society, notably in Saigon-Cho Lon. The progression of these activities during the process was observable, at least for those granted permission to participate. The requirements of the colonial environment and the vitality of the private sector fuelled these new activities, although the colonial authorities deemed it necessary to exert control over them. This article offers additional information on the printing and publishing activities in Saigon-Cho Lon, Vietnam, highlighting the accomplishments of some distinguished printers.