The fast-growing field of nanotheranostics is revolutionizing cancer treatment by allowing for precise diagnosis and targeted therapy at the cellular and molecular levels. These nanoscale platforms provide considerable benefits in oncology, including improved disease and therapy specificity, lower systemic toxicity, and real-time monitoring of therapeutic outcomes. However, nanoparticles' complicated interactions with biological systems, notably the immune system, present significant obstacles for clinical translation. While certain nanoparticles can elicit favorable anti-tumor immune responses, others cause immunotoxicity, including complement activation-related pseudoallergy (CARPA), cytokine storms, chronic inflammation, and organ damage. Traditional toxicity evaluation approaches are frequently time-consuming, expensive, and insufficient to capture these intricate nanoparticle-biological interactions. Artificial intelligence (AI) and machine learning (ML) have emerged as transformational solutions to these problems. This paper summarizes current achievements in nanotheranostics for cancer, delves into the causes of nanoparticle-induced immunotoxicity, and demonstrates how AI/ML may help anticipate and create safer nanoparticles. Integrating AI/ML with modern computational approaches allows for the detection of potentially dangerous nanoparticle qualities, guides the optimization of physicochemical features, and speeds up the development of immune-compatible nanotheranostics suited to individual patients. The combination of nanotechnology with AI/ML has the potential to completely realize the therapeutic promise of nanotheranostics while assuring patient safety in the age of precision medicine.

We studied the role of industry-academic collaboration (IAC) in the enhancement of educational opportunities and outcomes under the digital driven Industry 4.0 using research and development, the patenting of products/knowledge, curriculum development, and artificial intelligence as proxies for IAC. Relevant conceptual, theoretical, and empirical literature were reviewed to provide a background for this research. The investigator used mainly principal (primary) data from a sample of 230 respondents. The primary statistics were acquired through a questionnaire. The statistics were evaluated using the structural equation model (SEM) and Stata version 13.0 as the statistical software. The findings indicate that the direct total effect of Artificial intelligence (Aint) on educational opportunities (EduOp) is substantial (Coef. 0.2519916) and statistically significant (p < 0.05), implying that changes in Aint have a pronounced influence on EduOp. Additionally, considering the indirect effects through intermediate variables, Research and Development (Res_dev) and Product Patenting (Patenting) play crucial roles, exhibiting significant indirect effects on EduOp. Res_dev exhibits a negative indirect effect (Coef = −0.009969, p = 0.000) suggesting that increased research and development may dampen the impact of Aint on EduOp against a priori expectation while Patenting has a positive indirect effect (Coef = 0.146621, p = 0.000), indicating that innovation, as reflected by patenting, amplifies the effect of Aint on EduOp. Notably, Curriculum development (Curr_dev) demonstrates a remarkable positive indirect effect (Coef = 0.8079605, p = 0.000) underscoring the strong role of current development activities in enhancing the influence of Aint on EduOp. The study contributes to knowledge on the effective deployment of artificial intelligence, which has been shown to enhance educational opportunities and outcomes under the digital driven Industry 4.0 in the study area.

Artificial intelligence chatbots can be used to conduct research effectively and efficiently in the fifth industrial revolution. Artificial intelligence chatbots are software applications that utilize artificial intelligence technologies to assist researchers in various aspects of the research process. These chatbots are specifically designed to understand researchers’ inquiries, provide relevant information, and perform tasks related to data collection, analysis, literature review, collaboration, and more. The purpose of this study is to investigate the use of artificial intelligence chatbots for conducting research in the fifth industrial revolution. This qualitative study adopts content analysis as its research methodology, which is grounded in literature review incorporating insights from the researchers’ experiences with utilizing artificial intelligence. The findings reveal that researchers can use artificial intelligence chatbots to produce quality research. Researchers are exposed to various types of artificial intelligence chatbots that can be used to conduct research. Examples are information chatbots, question and answer chatbots, survey chatbots, conversational agents, peer review chatbots, personalised learning chatbots and language translation chatbots. Artificial intelligence chatbots can be used to perform functions such as literature review, data collection, writing assistance and peer review assistance. However, artificial intelligence chatbots can be biased, lack data privacy and security, limited in creativity and critical thinking. Researchers must be transparent and take in consideration issues of informed content and data privacy and security when using artificial intelligence chatbots. The study recommends a framework on artificial intelligence chatbots researchers can use to conduct research in the fifth industrial revolution.

This study comprehensively evaluates the system performance by considering the thermodynamic and exergy analysis of hydrogen production by the water electrolysis method. Energy inputs, hydrogen and oxygen production capacities, exergy balance, and losses of the electrolyzer system were examined in detail. In the study, most of the energy losses are due to heat losses and electrochemical conversion processes. It has also been observed that increased electrical input increases the production of hydrogen and oxygen, but after a certain point, the rate of efficiency increase slows down. According to the exergy analysis, it was determined that the largest energy input of the system was electricity, hydrogen stood out as the main product, and oxygen and exergy losses were important factors affecting the system performance. The results, in line with other studies in the literature, show that the integration of advanced materials, low-resistance electrodes, heat recovery systems, and renewable energy is critical to increasing the efficiency of electrolyzer systems and minimizing energy losses. The modeling results reveal that machine learning programs have significant potential to achieve high accuracy in electrolysis performance estimation and process view. This study aims to contribute to the production of growth generation technologies and will shed light on global and technological regional decision-making for sustainable energy policies as it expands.

Objectives: This research aimed to empirically examine the transformative impacts of Artificial Intelligence (AI) adoption on financial reporting quality in Jordanian banking, with internal controls as a hypothesized mediation mechanism. Methodology: Quantitative survey data was collected from 130 bank personnel. Multi-item reflective measures assessed AI adoption, internal controls, and financial reporting quality—structural equation modelling analysis relationships between constructs. Findings: The research tested four hypotheses grounded in agency and contingency theories. Confirmatory factor analysis demonstrated sound measurement models. Structural equation modelling revealed that AI adoption significantly transformed financial reporting quality. The mediating effect of internal controls on the AI-quality relationship was supported. Specifically, the path from AI adoption to quality was significant, indicating a positive impact. Despite internal controls strongly predicting quality, its mediating effect significantly shaped the degree of transformation driven by AI adoption. The indirect effect of AI on quality through internal controls was also significant. Findings imply a growing diffusion of AI applications in core financial reporting systems. Practical implications: Increasing AI applications focus on holistically transforming systems, reflecting committing adoption. Jordanian banks selectively leverage controls to moderate AI-induced transformations. Originality/value: This study provides essential real-world insights into how AI is adopted and impacts the Jordanian banking sector, a key player in a fast-evolving developing economy. By examining the role of internal controls, it deepens our understanding of how AI works in practice and offers practical advice for integrating technology effectively and improving information quality. Its mixed methods, unique context, and focus on AI’s impact on organizations significantly enrich academic literature. Recommendations: Banks should invest in integrated AI architectures, strategically strengthen critical controls to steer transformations, and incrementally translate AI innovations into core processes.

Artificial Intelligence (AI) has become a pivotal force in transforming the retail industry, particularly in the online shopping environment. This study investigates the impact of various AI applications—such as personalized recommendations, chatbots, predictive analytics, and social media engagement—on consumer buying behaviors. Employing a quantitative research design, data was collected from 760 respondents through a structured online survey. The snowball sampling technique facilitated the recruitment of participants, focusing on diverse demographics and their interactions with AI technologies in online retail. The findings reveal that AI-driven personalization significantly enhances consumer purchase intentions and satisfaction. Multiple regression analysis shows that AI personalization (β = 0.35, p < 0.001) has the most substantial impact on purchase intention, followed by chatbot effectiveness (β = 0.25, p < 0.001), predictive analytics (β = 0.20, p < 0.001), and social media engagement (β = 0.15, p < 0.01). Similarly, AI personalization (β = 0.30, p < 0.001), predictive analytics (β = 0.25, p < 0.001), and chatbot effectiveness (β = 0.20, p < 0.001) significantly influence consumer satisfaction. The hierarchical regression analysis underscores the importance of ethical considerations, showing that ethical and transparent use of AI increases consumer trust and engagement. Model 1 explains 45% of the variance in consumer behavior (R² = 0.45, F = 154.75, p < 0.001), while Model 2, incorporating ethical concerns, explains an additional 10% (R² = 0.55, F = 98.25, p < 0.001). This study highlights the necessity for retailers to leverage AI technologies ethically and effectively to gain a competitive edge, improve customer satisfaction, and drive long-term success. Future research should explore the long-term impacts of AI on consumer behavior and the integration of emerging technologies such as augmented reality and the Internet of Things (IoT) in retail.