With the development of globalization, the importance of multiculturalism in university English education is becoming more and more prominent. This paper discusses the problems related to the teaching innovation of university English education from the perspective of multiculturalism. Firstly, it introduces the concept and significance of multicultural education and emphasizes its importance to university English education. Secondly, it analyzes the problems existing in the current university English teaching, such as cultural prejudice and language barrier. Then, innovative strategies for multicultural teaching are proposed, including teacher training, textbook design, teaching activities and so on. Finally, the evaluation and future development of multicultural education are prospected.