Carbon-based hollow structured nanomaterials have become one of the hot areas for research and development of hollow structured nanomaterials due to their unique structure, excellent physicochemical properties and promising applications. The design and synthesis of novel carbon-based hollow structured nanomaterials are of great scientific significance and wide application value. The recent research on the synthesis, structure and functionalization of carbon-based hollow structured nanomaterials and their related applications are reviewed. The basic synthetic strategies of carbon-based hollow structure nanomaterials are briefly introduced, and the structural design, material functionalization and main applications of carbon-based hollow structure nanomaterials are described in detail. Finally, the current challenges and opportunities in the synthesis and application of carbon-based hollow structured nanomaterials are discussed.
The article examines the issues of application and improvement of the methodology for evaluating industrial enterprises as recipients of state support within the framework of the implementation of industrial policy. The authors considered approaches to the content of industrial policy, investigated the factors influencing its efficiency, identified aspects of its imperfections that arise when applying an incomplete list of important parameters of economic development and ambiguity in the interpretation of previously applied estimates. The article presents proposals to improve the methodology for assessing potential recipients of state support based on the development of a comprehensive indicator for assessing enterprises (recipients of support), taking into account not only the classical parameters of the economic efficiency of industrial enterprises applying for state financial assistance, but also such aspects as the development of budgetary funds, belonging to priority sectors of the economy, characteristics of sustainable development and export and innovation potential. Combining the results of a comprehensive assessment of the recipient of state support with a map of the business demography of the territory allows making a decision not only about the fact of support and its efficiency, but also to predict the assessment of the life cycle of the enterprise and its subsequent development.
Mapping land use and land cover (LULC) is essential for comprehending changes in the environment and promoting sustainable planning. To achieve accurate and effective LULC mapping, this work investigates the integration of Geographic Information Systems (GIS) with Machine Learning (ML) methodology. Different types of land covers in the Lucknow district were classified using the Random Forest (RF) algorithm and Landsat satellite images. Since the research area consists of a variety of landforms, there are issues with classification accuracy. These challenges are met by combining supplementary data into the GIS framework and adjusting algorithm parameters like selection of cloud free images and homogeneous training samples. The result demonstrates a net increase of 484.59 km2 in built-up areas. A net decrement of 75.44 km2 was observed in forest areas. A drastic net decrease of 674.52 km2 was observed for wetlands. Most of the wastelands have been converted into urban areas and agricultural land based on their suitability with settlements or crops. The classifications achieved an overall accuracy near 90%. This strategy provides a reliable way to track changes in land cover, supporting resource management, urban planning, and environmental preservation. The results highlight how sophisticated computational methods can enhance the accuracy of LULC evaluations.
To deal with problems of traditional geographic information collection, such as low real-time, poor authenticity of the data, and unclear description of detailed areas, a design scheme of remote sensing-based geographic information system is proposed. The system mainly consists of information collection, imaging processing, data storage management, scene control and data transmission module. By use of remote sensing technology, the reflected and radiated electromagnetic waves of the target area are collected from a long distance to form an image, and the hue–intensity–saturation (HIS) transformation method is used to enhance the image definition. Weighted fusion algorithm is adopted to process the details of the image. The spatial database stores and manages the text and image data respectively, and establishes the attribute self-correlation mechanism to render the ground objects in the picture with SketchUp software. Finally, using RS422 protocol to transmit information can achieve the effect of multi-purpose, and enhance the anti-interference of the system. The experimental results show that the practical experience of the proposed system is excellent, the geographic information image presented is clear, and the edge details are clearly visible, which can provide users with effective geographic information data.
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.
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