Due to the bounded rationality of decision-makers and the substitution effect of non-green products, retailers are not always profitable when selling green products. To assist retailers who may be disadvantaged in the game, this study constructs a two-stage green supply chain game model, considering the bounded rationality of decision-makers and the substitution effect of non-green products, and analyzes the impacts of two operational strategies that retailers can adopt—price-cutting strategy and early replenishment strategy. The research reveals that retailers tend to lower prices in the second stage when price reductions stimulate consumer purchases, enhancing their profitability. However, strategic retailers may raise prices in the first stage to create room for discounts later, potentially harming consumer interests. Contrary to expectations, anticipating future demand does not always improve supply chain profitability in the early replenishment strategy, which mainly depends on the market environment. Early replenishment deprives retailers of negotiation leverage in the second stage, and bulk orders may lead manufacturers to over-invest in green innovation. Therefore, this strategy is effective only when green innovation costs are low, consumer environmental awareness is high, or price sensitivity is low.

Human settlement patterns in the South are clearly inequitable and dysfunctional, with tenure insecurity remaining a significant issue. Consequently, there has been a dramatic increase in housing demand driven by rising household sizes and accelerated urbanization. Local governments have a clear mandate to ensure socio-economic development and promote democracy, which necessitates ongoing consultations and renegotiations with citizens. This paper critically examines the de-densification of informal settlements as a pivotal strategy to enhance the quality of life for citizens, all while maintaining essential social networks. Governments must take decisive action against pandemics by transforming spaces into liveable settlements that improve livelihoods. A qualitative method was employed, analyzing data drawn from interviews to gain insights into individual views, attitudes, and behaviors regarding the improvement of livelihoods in informal settlements. The study utilized a simple random sampling technique, ensuring that every individual in the population selected had an equal opportunity for inclusion. Semi-structured interviews were conducted with twenty community members in Cornubia, alongside discussions with three officials from eThekwini Municipality and KwaZulu Natal (KZN) Provincial Department of Human Settlements. Data was analyzed using thematic analysis, and the findings hold substantial benefits for the most disadvantaged citizens. Therefore, municipalities have an obligation to transform urban areas by reducing inequality, bolstered by national government policy, to achieve a resilient, safe, and accessible urban future. The evidence presented in this paper underscores that local governments, through municipalities, must prioritize de-densifying informal settlements in response to pandemics or hazards. It is vital to leverage community-driven initiatives and reinforce networks within these communities. The paper calls for the establishment of a socially centered government through the District Development Model (DDM), emphasizing socio-economic transformation as a pathway to enhance community quality of life.

With the main idea of cultivating people through the curriculum, this paper explores the organic integration of ideological and political lines and knowledge lines in the teaching design of pharmacology in higher vocational colleges. The medical humanistic literacy contained in the teaching design, explores the path and method of the ideological and political construction of the course, and combines the teaching of professional knowledge and the cultivation of theoretical skills with the cultivation of students’ patriotism, medical professional ethics, life awareness and scientific research spirit. Improve the educational effect of curriculum ideological and political education in college education.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.