Since the 20th National Congress, with the emphasis on innovation and entrepreneurship on country, innovation and entrepreneurship education has become an important part of talent training in universities. The constructivist learning concept advocates that students' learning should respect their own meaning construction, and social mutual assistance and situational construction to acquire knowledge. Based on the current issue of students' innovation and entrepreneurship, this article takes the constructivist learning perspective as a guide to explore strategies to enhance their innovation and entrepreneurship abilities, and is committed to promoting the improvement of their abilities.

With the main idea of cultivating people through the curriculum, this paper explores the organic integration of ideological and political lines and knowledge lines in the teaching design of pharmacology in higher vocational colleges. The medical humanistic literacy contained in the teaching design, explores the path and method of the ideological and political construction of the course, and combines the teaching of professional knowledge and the cultivation of theoretical skills with the cultivation of students’ patriotism, medical professional ethics, life awareness and scientific research spirit. Improve the educational effect of curriculum ideological and political education in college education.

In the context of digital transformation, Chinese small and medium sized enterprises (SMEs) face significant challenges and opportunities in adapting to market dynamics and technological advancements. This study investigates the impact of coopetition strategy on the core competencies of SMEs, with a particular focus on marketing, technological, and integrative competencies. Data were collected from a sample of 300 SMEs in Anhui Province through an online survey, and reliability and validity were tested using SPSS and AMOS. The results indicate that dependency and trust significantly enhance the effectiveness of coopetition strategy from an external perspective, while managerial ambidexterity and strategic intent are critical internal factors driving the successful implementation of coopetition strategies. Both external and internal factors positively impact the core competencies of SMEs. Additionally, environmental uncertainty moderates the relationship between coopetition strategy and core competencies, underscoring the need for flexibility and adaptability in dynamic market environments. The findings suggest that SMEs can better integrate internal and external resources, optimize resource allocation, and improve operational efficiency through coopetition strategy, thereby enhancing their core competencies. This study provides valuable insights and practical guidance for policymakers and business practitioners aiming to support the digital transformation of SMEs.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.