To save patients’ lives, it is important to go for an early diagnosis of intracranial hemorrhage (ICH). For diagnosing ICH, the widely used method is non-contrast computed tomography (NCCT). It has fast acquisition and availability in medical emergency facilities. To predict hematoma progression and mortality, it is important to estimate the volume of intracranial hemorrhage. Radiologists can manually delineate the ICH region to estimate the hematoma volume. This process takes time and undergoes inter-rater variability. In this research paper, we develop and discuss a fine segmentation model and a coarse model for intracranial hemorrhage segmentations. Basically, two different models are discussed for intracranial hemorrhage segmentation. We trained a 2DDensNet in the first model for coarse segmentation and cascaded the coarse segmentation mask output in the fine segmentation model along with input training samples. A nnUNet model is trained in the second fine stage and will use the segmentation labels of the coarse model with true labels for intracranial hemorrhage segmentation. An optimal performance for intracranial hemorrhage segmentation solution is obtained.
The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.
Herein, we report a facile preparation of super-hydrophilic sand by coating the sand particles with cross-linked polyacrylamide (PAM) hydrogels for enhanced water absorption and controlled water release aimed at desert agriculture. To prepare the sample, 4 wt% of aqueous PAM solution is mixed with organic cross-linkers of hydroquinone (HQ) and hexamethylenetetramine (HMT) in a 1:1 weight ratio and aqueous potassium chloride (KCl) solution. A specific amount of the above solution is added to the sand, well mixed, and subsequently cured at 150 °C for 8 h. The prepared super-hydrophilic sands were characterized by Fourier-transform infrared spectroscopy (FT-IR) for chemical composition and X-ray diffraction (XRD) for successful polymer coating onto the sand. The water storage for the samples was studied by absorption kinetics at various temperature conditions, and extended water release was studied by water desorption kinetics. The water swelling ratio for the super-hydrophilic sand has reached a maximum of 900% (9 times its weight) at 80 °C within 1 h. The desorption kinetics of the samples showed that the water can be stored for up to a maximum of 3 days. Therefore, super-hydrophilic sand particles were successfully prepared by coating them with PAM hydrogels, which have great potential to be used in sustainable desert agriculture.
In China, ideological and political education is currently the hot direction of teaching reform in various colleges and universities, yet the development of appropriate teaching evaluation methods needs to catch up. This study addresses the pressing need for a preliminary investigation into the complex relationships among ideological and political education, the students’ learning satisfaction and teaching quality. This research examines the influence of teaching and ideological and political education quality on students’ satisfactions by designing a set of scales, collecting about 3800 questionnaires. Utilizing Structural Equation Modeling (SEM) and qualitative interviews, this study reveals that the teaching quality directly affects students’ learning satisfaction and ideological and political education. Notably, ideological and political education can also affect students’ learning satisfaction. The findings underscore the importance of including ideological and political education assessments in evaluating courses. This research contributes to the ongoing dialogue on effective teaching evaluation methods in the context of evolving educational practices.
The effects of climate change are already being felt, including the failure to harvest several agricultural products. On the other hand, peatland requires good management because it is a high carbon store and is vulnerable as a contributor to high emissions if it catches fire. This study aims to determine the potential for livelihood options through land management with an agroforestry pattern in peatlands. The methods used are field observation and in-depth interviews. The research location is in Kuburaya Regency, West Kalimantan, Indonesia. Several land use scenarios are presented using additional secondary data. The results show that agroforestry provides more livelihood options than monoculture farming or wood. The economic contribution is very important so that people reduce slash-and-burn activities that can increase carbon emissions and threaten the sustainability of peatland.
The developmental dilemma of infant and toddler care is examined from a family perspective, and in-depth analyses of infant and toddler care are conducted using Family Systems Theory and Cultural Capital Theory,which are essential to the holistic development of children, the balance between family and work, and the sustainable development of society and the economy.The developmental dilemmas of infant and toddler care are discussed in depth from the family perspective, and solutions are proposed accordingly. By applying family systems theory and cultural capital theory to analyze the root causes and influencing factors of the problem, it provides useful thoughts and suggestions for improving infant and toddler care practices.
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