This research aims to solve the research problems regarding the most important value of an object in the form of the wedangan phenomenon. This research objectives to expose the superiority of the communities’ food consumption tradition in the form of wedangan. This research belongs to a qualitative study and uses ethnomethodology as an initial approach. It is because the initial data findings are in the form of an indexical conversation that explicitly refers to the concept of wedangan. The concept refers to wedangan in real life, which is in the form of eating and drinking activities while chatting. The research findings are: 1) the most profound structure of wedangan’s tradition is food provision and food eating; 2) wedangan accommodates three forms (food stall, street food, and restaurant); 3) wedangan also accommodates three food values (delightful, useful, and meritorious); and 4) there is an egalitarian consumption pattern in wedangan, people regardless their social class visiting the same place, eat the same food, being simple and be ordinary (or usually we call it as food marriage). Wedangan is a social activity with advantages from a social, economic, and political perspective. Therefore, this phenomenon requires more serious attention from the government.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.

An image adaptive noise reduction enhancement algorithm based on NSCT is proposed to perform image restoration preprocessing on the defocused image obtained under the microscope. Defocused images acquired under micro-nano scale optical microscopy, usually with inconspicuous details, edges and contours, affect the accuracy of subsequent observation tasks. Due to its multi-scale and multi-directionality, the NSCT transform has superior transform functions and can obtain more textures and edges of images. Combined with the characteristics of micro-nanoscale optical defocus images, the NSCT inverse transform is performed on all sub-bands to reconstruct the image. Finally, the experimental results of the standard 500 nm scale grid, conductive probe and triangular probe show that the proposed algorithm has a better image enhancement effect and significantly improves the quality of out-of-focus images.

The development of the personal innovative competences in workers is of capital importance for the competitiveness of organizations, where the ability of the employees must respond in an innovative way to diverse situations that arise in specific contexts. Considering this, the question arises: How do innovative employees' competences affect the sustainable development of Micro, Small and Medium Enterprises (MSMEs)? Therefore, the objective of this work is to present a multi-criteria method based on the Analytic Network Process (ANP), to relate innovative personal competences and the sustainable development of MSMEs. An instrument was applied to groups of experts from 31 Ecuadorian fruit-exporting MSMEs, to develop a multi-criteria decisional network that allowed identifying the innovative personal abilities that have the greatest impact on the sustainable development of these organizations. The results demonstrate the relevance of the elements of innovative personal competencies, with a cumulative participation of 39.15%, Sustainable Export Development with 32.18% and Improvements with 28.66%. It also presents three types of analysis: i) Global to establish the weight of each variable; ii) Influences, to establish solid cause-effect relationships between the variables and iii) Integrated. The most relevant innovative personal competences for sustainable development and improvements for exporting SMEs are teamwork, critical thinking, and creativity within the international context.

Working Capital Management (hereafter WCM) is the strategic tool that helps a company navigate through challenging economic growth, and influence its competitive performance. Thus, this study examines the impact of WCM on the competitiveness of firms operating in the non-financial sectors in Pakistan. We use the Generalized Method of Moments (GMM) technique to ensure the robustness of our results. The study findings reveal that both a large net trade cycle and surplus working capital have a substantial negative impact on firms’ competitiveness within their respective industries. These results suggest that companies should streamline their investments in working capital accounts and concentrate more resources on long-term projects that maximize value to improve their competitiveness compared to other companies. Therefore, firms that are effectively managing their short-term financial affairs are experiencing much better performance in all aspects of firm performance. The research findings highlight the urgent need for governmental initiatives designed to improve WCM practices in these industries. It is imperative for the management of  companies with excess net working capital to maximize their working capital efficiency, aligning it with industry standards to enhance competitiveness. Moreover, policymakers should prioritize easing access to financial alternatives that allow enterprises to maintain an efficient working capital structure without relying on excessive measures. Furthermore, policymakers should be cautious when determining minimum cash balance requirements in a cash-strapped economy where external financing is relatively more expensive than in other regional economies.