Silymarin, a bioactive compound derived primarily from the seeds and fruit of the milk thistle (Silybum marianum) plant, has garnered increasing attention in recent years due to its potential applications in agriculture. This comprehensive review explores the multifaceted role of silymarin in agricultural practices, shedding light on its chemistry, biological activities, and diverse applications. The chemical structure and properties of silymarin are elucidated, emphasizing its unique solubility, stability, and bioavailability, which render it suitable for agricultural use. A significant portion of the review is dedicated to examining the biological activities of silymarin, which encompasses its antioxidant properties. The underlying mechanisms responsible for these activities are explored, highlighting their potential as a natural solution for mitigating environmental stressors that adversely affect crop health and productivity. Illustrative examples from research studies and practical applications underscore its effectiveness in safeguarding agricultural yields and ensuring food security. Furthermore, the review delves into the potential of silymarin to enhance crop growth, yield, and quality. Mechanisms through which silymarin influences plant physiology and metabolism are examined, providing valuable insights into its role as a growth-promoting agent in agriculture. The review concludes with a forward-looking examination of the prospects of silymarin in agriculture, highlighting emerging trends and areas of innovation that hold promise for sustainable and resilient farming systems. In summary, this review consolidates the current body of knowledge surrounding silymarin’s potential in agriculture. It underscores the versatility of silymarin as a natural tool for crop protection, growth enhancement, and environmental sustainability, offering valuable insights for researchers, practitioners, and policymakers seeking innovative approaches to address the challenges of modern agriculture.

Agriculture is an industry that plays an essential role in economic development towards eliminating poverty issues, but foreign direct investment (FDI) inflows to this sector remain modest in Vietnam. This study analyzed the determinants of foreign direct investment in the agricultural sector into the Southern Key Economic Zone (KEZ) of Vietnam, which is considered the foreign direct investment magnet of Vietnam, but its FDI inflows into the agricultural sector have been consistently low, and has shown a downward trend in recent years. The study was based on a sample of 129 foreign investors of a total of 164 multinational enterprises (MNEs) in the agricultural sector, including representatives of the Board of Directors and representatives at the department level. The Partial Least Squares Structural Equation modeling (PLS-SEM) approach was used to test the hypotheses. Findings indicated that FDI attraction policies have the strongest impact on FDI inflows. This was followed by infrastructure, regional agriculture policies, public service quality, natural conditions, and human resources. This study suggests policy recommendations to improve foreign direct investment inflows into the agricultural sector of the Southern Key Economic Zone (KEZ) of Vietnam.