Clinical/methodological problem: The identification of clinically significant prostate carcinomas while avoiding overdiagnosis of low-malignant tumors is a challenge in routine clinical practice. Standard radiologic procedures: Multiparametric magnetic resonance imaging (MRI) of the prostate acquired and interpreted according to PI-RADS (Prostate Imaging Reporting and Data System Guidelines) is accepted as a clinical standard among urologists and radiologists. Methodological innovations: The PI-RADS guidelines have been newly updated to version 2.1 and, in addition to more precise technical requirements, include individual changes in lesion assessment. Performance: The PI-RADS guidelines have become crucial in the standardization of multiparametric MRI of the prostate and provide templates for structured reporting, facilitating communication with the referring physician. Evaluation: The guidelines, now updated to version 2.1, represent a refinement of the widely used version 2.0. Many aspects of reporting have been clarified, but some previously known limitations remain and require further improvement of the guidelines in future versions.

This review focuses on ferrites, which are gaining popularity with their unique properties like high electrical resistivity, thermal stability, and chemical stability, making them suitable for versatile applications both in industry and in biomedicine. This review is highly indicative of the importance of synthesis technique in order to control ferrite properties and, consequently, their specific applications. While synthesizing the materials with consideration of certain properties that help in certain methods of preparation using polyol route, green synthesis, sol-gel combustion, or other wise to tailor make certain properties shown by ferrites, this study also covers biomedical applications of ferrites, including magnetic resonance imaging (MRI), drug delivery systems, cancer hyperthermia therapy, and antimicrobial agents. This was able to inhibit the growth of all tested Gram-negative and positive bacteria as compared with pure ferrite nanoparticles without Co, Mn or Zn doping. In addition, ferrites possess the ability to be used in environmental remediation; such as treatment of wastewater which makes them useful for high-surface-area and adsorption capacity due heavy metals and organic pollutants. A critical analysis of functionalization strategies and possible applications are presented in this work to emphasize the capability of nanoferrites as an aid for the advancement both biomedical technology and environmental sustainability due to their versatile properties combined with a simple, cost effective synthetic methodology.

Biomimicry is increasingly being used to drive sustainable constructional development in recent years. By emulating the designs and processes of nature, biomimicry offers a wealth of opportunities to create innovative and environmentally friendly solutions. Biomimicry in industrial development: versatile applications, advantages in construction. The text emphasizes the contribution of bio-mimetic technologies to sustainability and resilience in structural design, material selection, energy efficiency, and sensor technology. Aside from addressing technical constraints and ethical concerns, we address challenges and limitations associated with adopting biomimicry. A quantitative research approach is implemented, and respondents from the construction industry rank biomimicry principles as the optimal approach to enhance sustainability in the industry. Demographic and descriptive analyses are underway. By working together, sharing knowledge, and innovating responsibly, we suggest approaches to tackle these obstacles and fully leverage the transformative power of biomimicry in promoting sustainable construction industry practices. In an evolving global environment, biomimicry reduces environmental impact and enhances efficiency, resilience, and competitiveness in construction industries.

This paper uses a new cross-country cross-industry dataset on investment in tangible and intangible assets for 18 European countries and the US.  We set out a framework for measuring intangible investment and capital stocks and their effect on output, inputs and total factor productivity. The analysis provides evidence on the diffusion of intangible investment across Europe and the US over the years 2000-2013 and offers growth accounting evidence before and after the Great Recession in 2008-2009. Our major findings are the following. First, tangible investment fell massively during the Great Recession and has hardly recovered, whereas intangible investment has been relatively resilient and recovered fast in the US but lagged behind in the EU. Second, the sources of growth analysis including only national account intangibles (software, R&D, mineral exploration and artistic originals), suggest that capital deepening is the main driver of growth, with tangibles and intangibles accounting for 80% and 20% in the EU while both account for 50% in the US, over 2000-2013. Extending the asset boundary to the intangible assets not included in the national accounts (Corrado, Hulten and Sichel (2005)) makes capital deepening increase. The contribution of tangibles is reduced both in the EU and the US (60% and 40% respectively) while intangibles account for a larger share (40% in EU and 60% in the US). Then, our analysis shows that since the Great Recession, the slowdown in labour productivity growth has been driven by a decline in TFP growth with relatively a minor role for tangible and intangible capital. Finally, we document a significant correlation between stricter employment protection rules and less government investment in R&D, and a lower ratio of intangible to tangible investment.

The ongoing railway reforms in Ukraine are crucial for the country’s integration into the European Union’s transportation network. A major challenge lies in the difference in track gauge widths: Ukraine predominantly uses a 1520 mm gauge, while European countries utilize a 1435 mm gauge. This 85 mm difference presents significant logistical and operational barriers, hindering smooth cross-border trade and travel. The study examines the current state of Ukraine’s railway system, highlighting the urgent need for infrastructure modernization to meet European standards. Methods include a comparative analysis of Ukraine’s railway network with those of EU member states, focusing on integration challenges and potential solutions. Results indicate that aligning Ukraine’s railway with European standards could substantially enhance connectivity, reduce transit times, and foster economic growth. However, “Ukrzaliznytsia’s” slow adaptation to these necessary changes is a major roadblock. The study concludes that the construction of a standard-gauge railway linking Ukraine to the EU is vital not only for improving trade routes but also for supporting Ukraine’s broader political and economic aspirations towards EU membership. Circular economy principles, such as resource optimisation, extending the life cycle of existing infrastructure and reusing materials from dismantled railway facilities, can offer a cost-effective and sustainable approach. This infrastructural change will serve as a catalyst for deeper integration, strengthening Ukraine’s position within the European transportation network.

The development of the maize agribusiness system is highly dependent on the role of social capital in facilitating interaction among actors in the chain of activities ranging from the provision of farm supplies to marketing. Therefore, this research aimed to characterize the key elements of social capital specifically bonding, bridging, and linking, as well as to demonstrate their respective roles. Data were collected from farmers and non-farmers actors engaged in various activities in the maize agribusiness system. The data obtained were processed using ATLAS Ti, applying open, axial, and selective coding techniques. The results showed the roles played by bonding, bridging, and linking social capital in the interaction between farmers and multiple actors in activities such as providing farm supplies, farming production, harvesting, post-harvest, and marketing. The combination of these social capital forms acted as the glue and wires that facilitated access to resources, collective decision-making, and reduced transaction costs. These results have theoretical implications, suggesting that bonding, bridging, and linking should be combined with the appropriate role composition for each activity in the agribusiness system.