This review discusses the significant progress made in the development of CNT/GO-based biosensors for disease biomarker detection. It highlights the specific applications of CNT/GO-based biosensors in the detection of various disease biomarkers, including cancer, cardiovascular diseases, infectious diseases, and neurodegenerative disorders. The superior performance of these biosensors, such as their high sensitivity, low detection limits, and real-time monitoring capabilities, makes them highly promising for early disease diagnosis. Moreover, the challenges and future directions in the field of CNT/GO-based biosensors are discussed, focusing on the need for standardization, scalability, and commercialization of these biosensing platforms. In conclusion, CNT/GO-based biosensors have demonstrated immense potential in the field of disease biomarker detection, offering a promising approach towards early diagnosis. Continued research and development in this area hold great promise for advancing personalized medicine and improving patient outcomes.

This study presents a comprehensive two-dimensional numerical analysis of natural laminar convection within a square cavity containing two circular heat sources, which simulate electric cables generating heat due to Joule heating. This scenario is particularly relevant in aeronautics, where excessive heating of electrical installations can lead to significant material and human safety risks. The primary objective of this research is to identify the optimal spacing between the two heat sources to mitigate the risk of overheating and ensure the safe operation of the electrical installation. To achieve this, various configurations were analyzed by adjusting the distance between the heat sources while also varying the Rayleigh number across a range from 10³ to 10⁶. The governing equations for the fluid flow and heat transfer were solved using a FORTRAN-based numerical code employing the finite volume method. The results indicate that the heat transfer characteristics within the cavity are significantly influenced by both the distance between the heat sources and the Rayleigh number. The analysis revealed that the average Nusselt number (Nu_avg) peaked at a value of 14.69 when the distance between the heat sources was set at 0.7 units and the Rayleigh number was at 10⁶. This finding suggests that maintaining this specific spacing between the electrical cables can optimize heat dissipation and enhance the safety of the installation. In conclusion, the study recommends adopting a spacing of 0.7 units between the electrical cables to ensure optimal thermal performance and minimize the risk of overheating, thereby safeguarding both the materials and personnel involved in aeronautical operations.

The study examines the impact of various theories on the reflection and transmission phenomena caused by obliquely incident longitudinal and transverse waves at the interface between a continuously elastic solid half-space and a thermoelastic half-space, using multiple thermoelastic models. Numerical calculations reveal that the thermoelastic medium supports one transmitted transverse wave and two transmitted longitudinal waves. The modulus of amplitude proportions is analyzed as a function of the angle of incidence, showing distinct variations across the studied models. Energy ratios, derived from wave amplitudes under consistent surface boundary conditions for copper, are computed and compared across angles of incidence. The results demonstrate that the total energy ratio consistently sums to one, validating energy conservation principles. Graphical comparisons of amplitude proportions and energy ratios for SV and P waves across different models illustrate significant differences in wave behavior, emphasizing the influence of thermoelastic properties on wave transmission and reflection.

Optimizing Storage Location Assignment (SLA) is essential for improving warehouse operations, reducing operational costs, travel distances and picking times. The effectiveness of the optimization process should be evaluated. This study introduces a novel, generalized objective function tailored to optimize SLA through integration with a Genetic Algorithm. The method incorporates key parameters such as item order frequency, storage grouping, and proximity of items frequently ordered together. Using simulation tools, this research models a picker-to-part system in a warehouse environment characterized by complex storage constraints, varying item demands and family-grouping criteria. The study explores four scenarios with distinct parameter weightings to analyze their impact on SLA. Contrary to other research that focuses on frequency-based assignment, this article presents a novel framework for designing SLA using key parameters. The study proves that it is advantageous to deviate from a frequency-based assignment, as considering other key parameters to determine the layout can lead to more favorable operations. The findings reveal that adjusting the parameter weightings enables effective SLA customization based on warehouse operational characteristics. Scenario-based analyses demonstrated significant reductions in travel distances during order picking tasks, particularly in scenarios prioritizing ordered-together proximity and group storage. Visual layouts and picking route evaluations highlighted the benefits of balancing frequency-based arrangements with grouping strategies. The study validates the utility of a tailored generalized objective function for SLA optimization. Scenario-based evaluations underscore the importance of fine-tuning SLA strategies to align with specific operational demands, paving the way for more efficient order picking and overall warehouse management.

Over the past 50 years, urban planning documents have been drawn up in sub-Saharan African cities without any convincing results. The study of secondary towns in Chad shows that these planning documents have been hampered by natural and man-made factors. The aim of this study is to determine the factors hindering the implementation of planning documents in the town of Pala in Chad. To carry out the study, a methodological approach (using quantitative and qualitative data) based on a questionnaire and interview survey was deployed for data collection. With a sample of 300 households surveyed, the main conclusions of the study show that all the factors identified, such as water erosion with a rate of 17.7 T/Ha/year, expose the town to various risks. Demographics, on the other hand, represent a lesser and therefore acceptable challenge. As far as exogenous factors are concerned, the level of education of the head of household is a determining factor in the implementation and acceptance of urban planning documents in Pala. Confirmatory factor analysis and the Chi² test revealed that consideration of stakeholders’ needs and their inclusion in the process of drawing up these documents are factors that significantly influence their implementation. In contrast, age, gender and other variables did not reveal any significant anomalies in our analyses. Consequently, future efforts to implement Pala’s planning documents must be based on community participation and awareness of the acceptance of these documents, which are necessary in a process of decentralization and urban planning.