In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

In order to explore the application of the new integrated intelligent spore capture system developed in China in the prediction of cucumber downy mildew and cucumber powdery mildew, the main working parameters of the integrated intelligent spore capture system, such as the presence or absence of air cutting head, the height of air collection port and the time of air collection, were optimized by identifying the morphology of captured spores in the case of natural disease in the field. The relationship between the disease index of cucumber downy mildew and cucumber powdery mildew in greenhouse and the amount of spores captured was analyzed through the dynamic monitoring of disease and spores. The results show that when the air cutting head is not installed, the height of the air collection port is 70 cm, and the period of 10: 00–10: 30 was beneficial to the capture of spores. The disease index of cucumber downy mildew and cucumber powdery mildew had a strong positive correlation with the total amount of spores captured for 7 consecutive days. Continuous monitoring of cucumber downy mildew sporangia and rapid increase in the number is a predictor of the occurrence or rapid increase of cucumber downy mildew. The conidia of cucumber powdery mildew were not detected before the disease onset, and the number of conidia captured was still small at the peak of the disease. The research shows that the integrated intelligent spore capture system is suitable for the prediction of cucumber downy mildew, but there are still some problems in the prediction of cucumber powdery mildew.

In the highly developed process of "Internet plus", foreign trade transformation and upgrading, cross-border new retail rapid development has become the trend of the times, cross-border e-commerce new retail digitalization, and improving operational efficiency brings new opportunities. Reshaping the structure of new retail formats, the integration of cross-border e-commerce and new retail formats is an inevitable trend. Smart upgrading and digital transformation are important measures to achieve leapfrog development. The format structure presents business models such as "smart retail, digital cross-border e-commerce, new cross-border e-commerce, new retail, and new retail logistics". The main research objective of this project is to explore and research the new retail scenarios of digital applications in cross-border e-commerce. Based on the current development trend of digital cross-border e-commerce and new retail upgrading, as well as the economic characteristics of the Wuyi area in Jiangmen City, this project aims to use the smart new retail scenario of digital cross-border e-commerce as the foothold, with a focus on upgrading and transforming the product flow chain with the "application scenario" as the central point, form a closed-loop loop of free circulation of products, new retail logistics, cross-border e-commerce, new retail, new sales experience scenarios, and consumers.

Adult obesity is a significant health problem, with nearly a quarter of Hungarian citizens aged 15 years and older being obese in 2019 (KSH, 2019a). The use of mobile devices for health purposes is increasing, and many m-health apps target weight-related behaviours. This study uniquely examines the effectiveness and user satisfaction of health-oriented apps among Hungarian adults, with a focus on health improvement. Using a mixed-methods approach, the study identifies six key determinants of health improvement and refines measurement tools by modifying existing parameters and introducing new constructs. The principal objective was to develop a measurement instrument for the usability of nutrition, relaxation and health promotion applications. The research comprised three phases: (1) qualitative content analysis of 13 app reviews conducted in June 2022; (2) focus group interviews involving 32 students from the fields of business, economics and health management; and (3) an online survey (n = 348 users) conducted in December 2023 that included Strava (105 users), Yazio (109 users) and Calm (134 users). Six factors were identified as determinants of health improvement: physical activity, diet, weight loss, general well-being, progress, and body knowledge. The LAUQ (Lifestyle Application Usability Questionnaire) scale was validated, including 'ease of use' (5 items), 'interface and satisfaction' (7 items) and 'modified usefulness and effectiveness' (9 items), with modifications based on qualitative findings. This research offers valuable insights into the factors influencing health improvement and user satisfaction with healthy lifestyle-oriented applications. It also contributes to the refinement of measurement tools such as the LAUQ, which will inform future studies in health psychology, digital health, and behavioural economics.

This paper presents an effective method for performing audio steganography, which would help in improving the security of information transmission. Audio steganography is one of the techniques for hiding secret messages within an audio file to maintain communication secrecy from unwanted listeners. Most of these conventional methods have several drawbacks related to distortion, detectability, and inefficiency. To mitigate these issues, a new scheme is presented which combines the techniques of image interpolation with LSB encoding. It selects non-seed pixels to allow reversibility and diminish distortion in medical images. Our technique also embeds a fragile watermarking scheme to identify any breach during transmission to recover data securely and reliably. A magic rectangle has also been used for encryption to enhance data security. This paper proposes a robust, low-distortion audio steganography technique that provides high data integrity with undetectability and will have wide applications in sectors like e-healthcare, corporate data security, and forensic applications. In the future, this approach will be refined for broader audio formats and overall system robustness.

The main reason for the formation of nano-biotechnology is due to the penetration of nanotechnology in the biological field, nanotechnology research center is the study of nano-drug carrier. Nano-drug system targeted drug delivery to achieve drug release, increase the insoluble drugs and peptide drug bio-efficiency, reduce the toxicity and application of drugs and other aspects of the development of good prospects, and thus become one of the key research in recent years’ field. Synthesis and application of nanometer drug carriers this review is presented in recent years and its application to provide a comprehensive basis for the treatment process. Describes the nature and preparation of nano-drug carrier methods, in recent years, people have been widely concerned by scholars. Compared with the nano-drug delivery, the general pharmaceutical cannot have to extend the role of drugs, strong efficacy, and the advantages of small drug response. Nano-materials, the specific surface area, surface activity, high catalytic efficiency, surface active center, adsorption capacity and other characteristics, which has many excellent features and new features.