Nanotechnology is a subject that studies, processes, and applies various functional materials, equipment, and systems, and controls substances on a nanoscale. Nanomedicine refers to its application in diagnosing, treating, preventing, and monitoring various diseases. Drugs administered through eye drops must travel a long distance to avoid various eye barriers reaching the posterior segment of the eye, to achieve the lowest drug level. This review focuses on nanotechnology-based eye disease treatment systems and highlights the obstacles affecting the drug management of eyes and nano-systems for the treatment of eye diseases. This paper summarizes the development prospect of nanotechnology and the challenges it faces in the treatment and diagnosis of ophthalmic diseases, to provide information and new ideas for the implementation of treatment and the development of a refractory eye disease management system.
The global adoption of sustainable development practices is gaining momentum, with an increasing emphasis on balancing the social, economic, and environmental pillars of sustainability. This study aims to assess the current state of these pillars within the uMlalazi Local Municipality, South Africa, and evaluate the initiatives in place to address related challenges. The purpose is to gain a deeper understanding of how effectively these three pillars are being addressed in the context of local governance. Using qualitative research methods, the study gathered data from a sample of five key informants, including three local government officials, one councillor, and one chief information officer from the local police. Data was collected through open-ended interview questions, with responses recorded, transcribed, and analysed for thematic content. The findings reveal significant gaps in the municipality’s approach to sustainability, including the absence of formalized trading areas, limited community input in planning and decision-making, high crime rates, and persistent unemployment. These issues were found to be interlinked with other challenges, such as inefficiencies in solid waste management. Additionally, the study confirms that the three pillars of sustainability are not treated equally, with economic and social aspects often receiving less attention compared to environmental concerns. This highlights the need for the municipality to focus on formalizing trading areas, encouraging local economic growth, and enhancing public participation in governance. By implementing incentives for greater community involvement and addressing the imbalances between the sustainability pillars, uMlalazi can make significant progress toward achieving more sustainable development.
The debate on relocating Indonesia’s national capital from Jakarta stems from critical issues such as overpopulation, social inequality, environmental degradation, and natural disaster risks. These challenges highlight the need to reassess Jakarta’s viability as the nation’s administrative center. This study evaluates Indonesia’s readiness to address the complexities of relocation by analyzing Jakarta’s socio-economic, political, cultural, and geographical conditions. Using a systematic literature review (SLR) with a qualitative approach, the research explores key questions: Do Jakarta’s conditions necessitate relocation? What challenges might arise from the move? How prepared is Indonesia to tackle these challenges? The SLR process includes defining questions, sourcing literature from reputable databases, applying inclusion/exclusion criteria, and synthesizing data for analysis. Findings reveal Jakarta’s multifaceted challenges, including social disparities, environmental degradation, disaster risks, and governance issues, which emphasize the urgency of considering relocation. However, the study also identifies significant hurdles, such as high costs, logistical complexities, potential social conflicts, and environmental risks at the new capital site. Relocating the capital is a strategic and complex undertaking that requires meticulous planning. Indonesia must weigh Jakarta’s current issues, address potential relocation challenges, and ensure readiness for risk mitigation and sustainable development. Comprehensive and thoughtful planning is essential to achieve a successful and balanced transition.
The objective of this work was to evaluate the combined effect of bovine manure, Pseudomonas putida and Trichoderma aureoviride on the development of lettuce (Lactuca sativa). The promotion of plant growth by microorganisms may be a viable and sustainable alternative for lettuce crop management. The experimental design was entirely randomized with five treatments: T0 (witness without fertilization, P. putida and T. aureoviride), TE (cattle manure), TEB (cattle manure + P. putida), TEF (cattle manure + T. aureoviride), TEFB (cattle manure + P. putida + T. aureoviride) and ten repetitions each. The following variables were analyzed: germination velocity index (GVI), first count (FC), germination percentage (GP), leaf area index and productivity. The TEFB treatment proved to be a viable alternative for the production of lettuce, especially for small producers, since all the vegetable production in the region comes from family farming.
The process of digitalization within the realm of tourism is not merely a trend but rather a significant catalyst that is rapidly propelling the comprehensive transformation of the tourism industry into a new era of technological advancement. This intricate process fundamentally involves the seamless integration and application of cutting-edge digital technologies across various tourism-related activities and services. The advent of innovative solutions that harness the immense capabilities of artificial intelligence, the analytical power of big data, the security features of blockchain, and the interconnectedness provided by the Internet of Things primarily serves to enhance the overall quality of services offered, optimize pricing strategies to align with market demands, and improve risk management protocols within the industry. This paper methods uses 100 Scopus indexed papers about Smart Tourism Development in Kazakhstan. It is imperative to underscore the fact that the ongoing digitalization process, while offering numerous advantages, simultaneously imposes rigorous new requirements concerning the qualifications and competencies of staff members, as well as the paramount importance of data security measures and the protection of consumer rights in the digital environment. The effective management of this digital transformation necessitates a holistic and integrated approach that encompasses not only the development of robust infrastructure but also the enhancement of digital literacy among employees and the establishment of a dynamic and innovative ecosystem that encourages creativity and adaptability.
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