In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

Cellulose nanocrystal, known as CNCs, is a form of material that can be produced by synthesizing carbon from naturally occurring substances, such as plants. Due to the unique properties it possesses, including a large surface area, impressive mechanical strength, and the ability to biodegrade, it draws significant attention from researchers nowadays. Several methods are available to prepare CNC, such as acid hydrolysis, enzymatic hydrolysis, and mechanical procedures. The characteristics of CNC include X-ray diffraction, transmission electron microscopy, dynamic light scattering, etc. In this article, the recent development of CNC preparation and its characterizations are thoroughly discussed. Significant breakthroughs are listed accordingly. Furthermore, a variety of CNC applications, such as paper and packaging, biological applications, energy storage, etc., are illustrated. This study demonstrates the insights gained from using CNC as a potential environmentally friendly material with remarkable properties.

Land use or land cover (LU/LC) mapping serves as a kind of basic information for land resource study. Detecting and analyzing the quantitative changes along the earth’s surface has become necessary and advantageous because it can result in proper planning, which would ultimately result in improvement in infrastructure development, economic and industrial growth. The LU/LC pattern in Madurai City, Tamil Nadu, has undergone a significant change over the past two decades due to accelerated urbanization. In this study, LU/LC change dynamics were investigated by the combined use of satellite remote sensing and geographical information system. To understand the LU/LC change in Madurai City, different land use categories and their spatial as well as temporal variability have been studied over a period of seven years (1999-2006), by analyzing Landsat images for the years 1999 and 2006 respectively with the help of ArcGIS 9.3 and ERDAS Imagine 9.1 software. This results show that geospatial technology is able to effectively capture the spatio-temporal trend of the landscape patterns associated with urbanization in this region.

This study was carried out at the Teaching and Research Farm of Landmark University, Omu-Aran. Treatments consisted of 3 levels of cocoa pod husk ash (0, 2 and 4 tonnes CPHA ha^-1), 3 levels of cocoa pod husk powder (0, 2 and 4 tonnes CPHP ha^-1), NPK and the control. The experiment was laid out in a Randomized Complete Block Design (RCBD) replicated four times. The following parameters were taken plant height, number of leaves (at 2, 3, and 4 weeks after sowing), total plant weight, root weight, leaf weight, roots girth and roots length. Data collected were subjected to Analysis of Variance (ANOVA) Using S.A.S, 2000. Treatment means were compared using Duncan Multiple Range Test (DMRT) at 0.05 level of probability. Results showed that chemical analysis of cocoa pod ash and powder contained plant nutrients as N, P, K, Ca, Mg and some other micronutrients in varying proportions. Application of CPHA 4 + CPHP 2 gave higher values for all the vegetative parameters. The implication of this study is that high level of cocoa pod husk powder in combination with high level of cocoa pod husk ash is detrimental to radish cultivation. In the same vein, the nutrition of radish was incomplete when NPK fertilizer was applied. It can therefore be recommended that the use of combined application of cocoa pod ash and cocoa pod powder at CPHA4 + CPHP2 was sufficient for the cultivation of radish (Raphanus sativus) in the study area as it compete favorably with application of NPK fertilizer.