Fungi can be used to remove or degrade polluting compounds through a mycoremediation process. Sometimes even more efficiently than prokaryotes, they can therefore be used to combat pollution from non-biodegradable polymers. Cellulose acetate is a commonly used material in the manufacture of cigarette butts, so when discarded, it generates pollution. The fungus Pleurotus ostreatus has the ability to degrade cellulose acetate through the enzymes it secretes. The enzyme hydrolyzes the acetyl group of cellulose acetate, while cellulolytic enzymes degrade the cellulose backbone into sugars, polysaccharides, or cellobiose. In addition to cellulose acetate, this fungus is capable of degrading other conventionally non-biodegradable polymers, so it has the potential to be used to reduce pollution. Large-scale cultivation of the fungus has proven to be more economically viable than conventional methods for treating non-biodegradable polymers, which is an additional advantage.

Instant and accurate evaluation of drug resistance in tumors before and during chemotherapy is important for patients with advanced colon cancer and is beneficial for prolonging their progression-free survival time. Here, the possible biomarkers that reflect the drug resistance of colon cancer were investigated using proton magnetic resonance spectroscopy (1H-MRS) in vivo. SW480[5-fluorouracil(5-FU)-responsive] and SW480/5-FU (5-FU-resistant) xenograft models were generated and subjected to in vivo 1H-MRS examinations when the maximum tumor diameter reached 1–1.5 cm. The areas under the peaks for metabolites, including choline (Cho), lactate (Lac), glutamine/glutamate (Glx), and myo-inositol (Ins)/creatine (Cr) in the tumors, were analyzed between two groups. The resistance-related protein expression, cell morphology, necrosis, apoptosis, and cell survival of these tumor specimens were assessed. The content for tCho, Lac, Glx, and Ins/Cr in the tumors of the SW480 group was significantly lower than that of the SW480/5-FU group (P < 0.05). While there was no significant difference in the degree of necrosis and apoptosis rate of tumor cells between the two groups (P > 0.05), the tumor cells of the SW480/5-FU showed a higher cell density and larger nuclei. The expression levels of resistance-related proteins (P-gp, MPR1, PKC) in the SW480 group were lower than those in the SW480/5-FU group (P < 0.01). The survival rate of 5-FU-resistant colon cancer cells was significantly higher than that of 5-FU-responsive ones at 5-FU concentrations greater than 2.5 μg/mL (P < 0.05). These results suggest that alterations in tCho, Lac, Glx1, Glx2, and Ins/Cr detected by 1H-MRS may be used for monitoring tumor resistance to 5-FU in vivo.

Metal iodide materials as novel components of thermal biological and medical systems at the interface between heat transfer techniques and therapeutic systems. Due to their outstanding heat transfer coefficients, biocompatibility, and thermally activated sensitivity, metal iodides like silver iodide (AgI), copper iodide (CuI), and cesium iodide (CsI) are considered to be useful in improving the performance of medical instruments, thermal treatment processes, and diagnostics. They are examined for their prospective applications in controlling thermal activity, local heating therapy, and smart temperature-sensitive drug carrier systems. In particular, their application in hyperthermia therapy for cancer treatment, infrared thermal imaging for diagnosis, and nano-based drug carriers points to a place for them in precision medicine. But issues of stability of materials used, biocompatibility, and control of heat—an essential factor that would give the tools the maximum clinical value—remain a challenge. The present mini-review outlines the emerging area of metal iodides and their applications in medical technologies, with a special focus on the pivotal role of these materials in enhancing non-invasive, efficient, and personalized medicine. Over time, metal iodide-based systems scouted a new era of thermal therapies and diagnostic instrumentation along with biomedical science as a whole.

Disinformation can be defined as false information deliberately initiated to cause harm to a person, social group, organization, or country. Gendered disinformation then attacks or undermines people based on gender or weaponizes gendered narratives for political, social, or economic objectives. Gendered disinformation comes in different forms, such as harmful social media posts and graphics, sexual fabrications, and other forms of conspiracy theories. It is used in various situations and at different places. This research discussed the instances of gendered disinformation and harmful online narratives that are recognizable and visible. It sheds light on the potential direct and indirect impact on youth experiences. In this study, the young participants (aged 18–30) focused on the instances of the existing online narratives of gendered discrimination from Belgium, Greece, Latvia, Spain, and Türkiye. The research provided an initial analysis of what “gendered information and harmful online narratives” look like and some recommendations from youth perspectives on countering the issues. The study concluded that there is a need for more research, further harmonization of legal frameworks, and strengthened capacity to detect gendered disinformation, propaganda, and hate speech.

In Nigeria, deforestation has led to an unimaginable loss of genetic variation within tree populations. Regrettably, little is known about the genetic variation of many important indigenous timber species in Nigeria. More so, the specific tools to evaluate the genetic diversity of these timber species are scarce. Therefore, this study developed species-specific markers for Pterygota macrocarpa using state-of-the-art equipment. Leaf samples were collected from Akure Forest Reserve, Ondo State, Nigeria. DNA isolation, quantification, PCR amplification, gel electrophoresis, post-PCR purification, and sequencing were done following a standardized protocol. The melting temperatures (TM) of the DNA fragments range from 57.5 ℃to 60.1 ℃ for primers developed from the MatK gene and 58.7 ℃ to 60.5 ℃ for primers developed from the RuBisCo gene. The characteristics of the ten primers developed are within the range appropriate for genetic diversity assessment. These species-specific primers are therefore recommended for population evaluation of Pterygota macrocarpa in Nigeria.