“Global South” is undoubtedly a broad term that typically refers to developing countries with varying degrees of economic, cultural and political influence. The rise of the Global South signifies the importance of reassessing the existing international order. In terms of international relations theory, this should be an innovative, progressive and reflective field of study. However, this research is predominantly led by the Western mainstream international relations theories. This often neglects the internal and external factors in the development processes of other countries, the formation of relationship frameworks, foreign policy formulation, and the need of foreign relations. Despite the ongoing and intense debate over the innovation of international relations theory, it is difficult to see it keeping pace with contemporary developments. Various schools and thoughts frequently innovate only within their foundational frameworks. Therefore, for Global South countries, there is the need for international relations theories that can reflect their specific needs and actual conditions. This does not only require breaking away from the westcentric theoretical framework, but ensuring that the innovation process is aligned with practical realities that recognize mutual interests and encompass both local and global perspectives. This approach should involve a comprehensive reflection on international relations, allowing innovation of international relations theories to genuinely “enter” the Global South countries.