Magnetite magnetic nanoparticles (MNP) exhibit superparamagnetic behavior, which gives them important properties such as low coercive field, easy superficial modification and acceptable magnetization levels. This makes them useful in separation techniques. However, few studies have experimented with the interactions of MNP with magnetic fields. Therefore, the aim of this research was to study the influence of an oscillating magnetic field (OMF) on polymeric monolithic columns with vinylated magnetic nanoparticles (VMNP) for capillary liquid chromatography (cLC). For this purpose, MNP were synthesized by coprecipitation of iron salts. The preparation of polymeric monolithic columns was performed by copolymerization and aggregation of VMNP. Taking advantage of the magnetic properties of MNP, the influence of parameters such as resonance frequency, intensity and exposure time of a OMF applied to the synthesized columns was studied. As a result, a better separation of a sample according to the measured parameters was obtained, so that a column resolution (R_s) of 1.35 was achieved. The morphological properties of the columns were evaluated by scanning electron microscopy (SEM). The results of the chromatographic properties revealed that the best separation of the alkylbenzenes sample occurs under conditions of 5.5 kHz and 10 min of exposure in the OMF. This study constitutes a first application in chromatographic separation techniques for future research in nanotechnology.

There are numerous studies reported on the usage of the sapindus emarginatus (SE) fruit in cancer and other treatments in the past few years. In this study, crude SE fruit extract was prepared and it was further used to synthesis gold nanoparticles (Au Nps). The synthesized Au Nps were left embedded in the SE fruit extract. The Au Nps embedded in the SE fruit extract (SE-Au Nps) were characterized using UV-Visiable Spectroscopy, Centrifugal Particle Size analyzer (CPS), Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). MTT assay was carried out for both SE fruit extract and SE-Au Nps on MCF7 breast cancer cell line and thus compared. The UV-Visible Absorbance for the SE-Au Nps was obtained at 543 nm. The centrifugal particle size analysis of the Au Nps embedded in SE fruit extract showed the size of the nanoparticles to be widely varying with higher fraction of particles between the size ranges of 15 to 20 nm. The morphology of the Au Nps embedded in SE fruit extract was observed using SEM. The presence of Au Nps in SE fruit extract was confirmed using FTIR. The results of the MTT assay on MCF7 breast cancer cell line proved that the % cell viability was less for SE-Au Nps than that of the SE fruit extract alone. Thus, the antiproliferative activity of the SE fruit extract was significantly enhanced by embedding it with Au Nps and it can be effectively used in therapeutic applications after further studies.

This review provided a detailed overview of the different synthesis and characterization methods of polymeric nanoparticles. Nanoparticles are defined as solid and colloidal particles of macromolecular substances ranging in size under 100 nm. Different types of nanoparticles are used in many biological fields (bio-sensing, biological separation, molecular imaging, anticancer therapy, etc.). The new features and functions provided by nano dimensions are largely different from their bulk forms. High volume/surface ratio, improved resolution and multifunctional capability make these materials gain many new features. 

The main reason for the formation of nano-biotechnology is due to the penetration of nanotechnology in the biological field, nanotechnology research center is the study of nano-drug carrier. Nano-drug system targeted drug delivery to achieve drug release, increase the insoluble drugs and peptide drug bio-efficiency, reduce the toxicity and application of drugs and other aspects of the development of good prospects, and thus become one of the key research in recent years’ field. Synthesis and application of nanometer drug carriers this review is presented in recent years and its application to provide a comprehensive basis for the treatment process. Describes the nature and preparation of nano-drug carrier methods, in recent years, people have been widely concerned by scholars. Compared with the nano-drug delivery, the general pharmaceutical cannot have to extend the role of drugs, strong efficacy, and the advantages of small drug response. Nano-materials, the specific surface area, surface activity, high catalytic efficiency, surface active center, adsorption capacity and other characteristics, which has many excellent features and new features.

This review provides an overview of the importance of nanoparticles in various fields of science, their classification, synthesis, reinforcements, and applications in numerous areas of interest. Normally nanoparticles are particles having a size of 100 nm or less that would be included in the larger category of nanoparticles. Generally, these materials are either 0-D, 1-D, 2-D, or 3-D. They are classified into groups based on their composition like being organic and inorganic, shapes, and sizes. These nanomaterials are synthesized with the help of top-down bottom and bottom-up methods. In case of plant-based synthesis i.e., the synthesis using plant extracts is non-toxic, making plants the best choice for producing nanoparticles. Several physicochemical characterization techniques are available such as ultraviolet spectrophotometry, Fourier transform infrared spectroscopy, the atomic force microscopy, the scanning electron microscopy, the vibrating specimen magnetometer, the superconducting complex optical device, the energy dispersive X-ray spectrometry, and X-ray photoelectron spectroscopy to investigate the nanomaterials. In the meanwhile, there are some challenges associated with the use of nanoparticles, which need to be addressed for the sustainable environment.

Protein- and peptide-based medications are recognized for their effectiveness and lower toxicity compared to chemical-based drugs, making them promising therapeutic agents. However, their application has been limited by numerous delivery challenges. Polymeric nanostructures have emerged as effective tools for protein delivery due to their versatility and customizability. Polymers’ inherent adaptability makes them ideal for meeting the specific demands of protein-delivery systems. Various strategies have been employed, such as enzyme inhibitors, absorption enhancers, mucoadhesive polymers, and chemical modifications of proteins or peptides. This study explores the hurdles associated with protein and peptide transport, the use of polymeric nanocarriers (both natural and synthetic) to overcome these challenges, and the techniques for fabricating and characterizing nanoparticles.