This qualitative research aimed to study the effectiveness of the local health constitution in controlling the spread of COVID-19. It reports the role of local communities, government agencies, and healthcare providers in implementing and enforcing local health constitutions and how their engagement can be improved to enhance surveillance. We also reported factors that influence compliance and strategies for improving compliance. We also evaluated the long-term sustainability of local health institutions beyond the pandemic. The population and sample group consisted of key members of the local health constitution teams at the provincial, sub-district, and village levels in the rural area of Ubon Ratchathani. Participants were purposively selected and volunteered to provide information. It included health science professionals, public health volunteers, community leaders, and local government officials, totaling 157 individuals. The study was conducted from December 2022 to September 2023. Our research shows that local health constitutions can better engage and educate communities to actively participate in pandemic surveillance and prevention. This approach is a learning experience for responding to emergencies, such as new infectious diseases that may arise in the future. This simplifies the work of officials, as everyone understands the guidelines for action. Relevant organizations contribute to disease prevention efforts, and there is sustainable improvement in work operations.

The H3N2 influenza virus is spiking dramatically, which is a major concern worldwide and in India. The multifunctional hetero-trimer influenza virus RNA-dependent RNA polymerase (RdRP) is involved in the generation of viral mRNA and is crucial for viral infectivity, which is directly related to the virus’s ability to survive. The goal of the current work was to use molecular docking to determine how the RdRP protein might be affected by powerful bioactive chemicals found in Calotropis gigantia latex. By applying CB-dock 2 analysis and 2D interactions, an in-silico docking study was conducted using a GC-FID (gas chromatography with flame-ionization detection) based composition profile. Tocospiro A (15%), Amyrin (7%), and Gombasterol A were found by GC-FID to be the main phytocompounds in the latex of Calotropis gigantia. The docking result showed that ligands were effectively bound to RdRP. According to interaction studies, RdRP/ligand complexes create hydrogen bonds, van der Waals forces, pi-alkyl bonds, alkyl bonds, and pi-Sigma bonds. Therefore, it was suggested that Calotropis gigantia latex may represent a possible herbal remedy to attenuate H3N2 infections based on the above findings of the fragrance profile and docking.

This article aims to explain the principles of the leadership styles of madrasah heads in enhancing the quality of Islamic education in Lhokseumawe City. It turns out that the leadership of madrasah heads has a significant impact on the functioning of the madrasah leadership. The madrasah head plays a direct role in developing Islamic educational institutions through leadership characteristics, leader types, leader functions, and leader activities during their tenure as madrasah heads. A quantitative research method with a phenomenological approach is considered capable of addressing various issues in the research problem formulation. It simultaneously analyzes data obtained from observations, interviews, and in-depth documentation to find answers to the research problem. The research findings reveal that the leadership styles of madrasah heads can be divided into two categories: democratic leadership style and autocratic leadership style. The first principle of leadership style involves giving responsibilities and authority to all parties, encouraging active involvement in the organization. Members are given opportunities to provide suggestions, recommendations, and criticisms for the progress of the organization. The second principle, the autocratic leadership style, positions a leader as the source of policies.