In recent years, the pathological diagnosis of glomerular diseases typically involves the study of glomerular his-to pathology by specialized pathologists, who analyze tissue sections stained with Periodic Acid-Schiff (PAS) to assess tissue and cellular abnormalities. In recent years, the rapid development of generative adversarial networks composed of generators and discriminators has led to further developments in image colorization tasks. In this paper, we present a generative adversarial network by Spectral Normalization colorization designed for color restoration of grayscale images depicting glomerular cell tissue elements. The network consists of two structures: the generator and the discriminator. The generator incorporates a U-shaped decoder and encoder network to extract feature information from input images, extract features from Lab color space images, and predict color distribution. The discriminator network is responsible for optimizing the generated colorized images by comparing them with real stained images. On the Human Biomolecular Atlas Program (HubMAP)—Hacking the Kidney FTU segmentation challenge dataset, we achieved a peak signal-to-noise ratio of 29.802 dB, along with high structural similarity results as other colorization methods. This colorization method offers an approach to add color to grayscale images of glomerular cell tissue units. It facilitates the observation of physiological information in pathological images by doctors and patients, enabling better pathological-assisted diagnosis of certain kidney diseases.

Disease epidemics may spread quickly and easily throughout nations and continents in our current global environment, having a devastating effect on public health and the world economy. There are over 513 million people worldwide who have been infected, and more than 6.2 million have died due to SARS-CoV-2. There are treatments but no cures for most viruses. Nevertheless, the spread of viruses can be limited by introducing antiviral coatings on public area surfaces and personal protective equipment (e.g., face masks). This work aims to fabricate a polymer-based coating with acrylic resin as a binder that possesses great antiviral activity against the Feline coronavirus (FCov). The chosen polymer, polyethylene glycol (PEG), is used as an antiviral agent because it contains “green” chemistry benefits such as non-toxicity, being inexpensive, readily recyclable, safe, natural, non-flammable, biocompatible, and biodegradable. The PEG/acrylic coating systems of different weight percentages were coated on the glass substrates by the spray-coating method and cured at room temperature for 24 hours. The developed PEG/acrylic coating system that contains 20 wt% of PEG exhibits the highest anti-viral activities (99.9% against FCov) compared to the other weight percentages. From this study, it has been observed that the hydrophilicity of the coating plays an important role in its antiviral activity. The developed coating has a hydrophilic property, in which the contact angle was measured at 83.28 ± 0.5°. The FTIR reveals that there are no existing toxic components or new components contained in the coating samples.

This research explores the implementation of streamlined licensing frameworks and consolidated procedures for promoting renewable energy generation worldwide. An in-depth analysis of the challenges faced by renewable energy developers and the corresponding solutions was identified through a series of industry interviews. The study aims to shed light on the key barriers encountered during project development and implementation, as well as the strategies employed to overcome these obstacles. By conducting interviews with professionals from the renewable energy sector, the research uncovers a range of common challenges, including complex permitting processes, regulatory uncertainties, grid integration issues, and financial barriers. These challenges often lead to project delays, increased costs, and limited investment opportunities, thereby hindering the growth of renewable energy generation. However, the interviews also reveal various solutions and best practices employed by industry stakeholders to address these challenges effectively. These solutions encompass the implementation of streamlined licensing procedures, such as single licenses and one-stop services, to simplify and expedite the permitting process. Additionally, the development of clear and stable regulatory frameworks, collaboration between public and private entities, and improved grid infrastructure were identified as key strategies to overcome regulatory and grid integration challenges. The research findings highlight the importance of collaborative efforts between policymakers, industry players, and other relevant stakeholders to create an enabling environment for renewable energy development. By incorporating the identified solutions and best practices, policymakers can streamline regulatory processes, foster public-private partnerships, and enhance grid infrastructure, thus catalyzing the growth of renewable energy projects.

The state delivery of affordable and sustainable housing continues to be a complicated challenge in Africa, and there is a need to encourage private sector participation. As a result, this study examines the risks associated with private sector participation in affordable housing and supporting infrastructure investment and the strategies towards mitigating the risks from an Afrocentric perspective. The evidence from a systematic literature review was coupled with the opinion of an international expert panel to address the paper’s aim and provide recommendations for developing improved housing and supporting infrastructure in Sub-Saharan Africa. The review outcomes and the qualitative data from the panel discussion were analysed using thematic analysis. The results revealed that market dynamics, land supply and acquisition constraints, cost of construction materials, unsupportive policies, and technical and financial factors constitute risks to affordable housing in the region. Mitigation strategies include leveraging joint efforts, strengths, and resource bases, increasing access to land and finance for private sector participation, developing a supportive government framework to promote an enabling environment for easy access to land acquisition and development finance, local production of building materials, research and technology adoption. In line with the United Nations (UN) Agenda 2030 targets and principles, reforms are required across the housing value chain, involving the private sector and community. Application of the study’s recommendations could minimise the risks of affordable housing delivery and enhance private sector participation.

The aim of the present study was to determine the effects of single and mixed infections of nematode (Meloidogyne javanica), fungus (Fusarium oxysporum) and bacterium (Xanthomonas axonopodis) on nodulation and pathological parameters of Bambara groundnut (Vigna subterrenea (L.) Verdc.) in field condition. Nematode infested field was used while other pathogens were obtained from diseased plants. The Randomized Complete Block Design (RCBD) was adopted in a 5 × 9 × 5 factorial design (5 blocks, 9 treatments and 5 replicates per treatments) resulting in 225 experimental units. In each experimental unit, three seeds were sown to a depth of 5cm and thinned to one plant per planting hole after germination at day 7. Treatments were inoculated into test plant following standard methods. As a result, the control treatment recorded the highest number of nodules (64.0 ± 6.91), followed by bacterium (45.2 ± 5.11) while N + F + B had the lowest number of root nodules (23.4 ± 2.42). Simultaneous treatment (N + F + B) gave the highest percentage reduction in nodulation (63.44%), followed by treatment N + F7 (56.25%). Fungus treatment recorded the highest mean wilted plants (3.8 + 0.20) followed by N + F7 treatment (3.40 + 0.40). Gall formation in the nematode treatment increased proportionately by 56.33% as the highest recorded, followed by treatment N + F7 with 50.0%. Treatment N + F7 had the highest reproduction factor (Rf) value of 9.30 followed by nematode (8.30), N + B7 (7.40), N + F + B (6.80) and N + F14 (6.50). Zero (0) Rf value was recorded in fungus, bacterium and control treatments. The observed differences in nodulation and pathological parameters among the treatments are significant (P < 0.05). The data provided in this work is important in the control of the three pathogens affecting the productivity of Bambara nut. Formulation of a single protectant should be designed to have potent effects on the three pathogens to achieve effective protection and good production of Bambara nut.

The Circular Economy (CE) concept has been recognized as the core strategy that can support sustainable business through technological innovation that enables CE transition by focusing on resource savings. This case study conducts research on business strategy in achieving CE transition in an agroindustry company, by performing SWOT analysis to assess internal and external factors. The SWOT model provides valuable results that an effective strategy could maximize strengths and opportunities, minimize weaknesses and threats in business by boosting circularity on business-critical factors. The CE adoption by agroindustry company mostly focuses on efficient organic waste management, energy-efficient production, and production process. This study case reveals that while technology plays a significant role in advancing CE, there is still a significant need to pay attention to the social aspect in supporting the creation of worker-owned cooperatives by creating space for employee involvement in finding innovations and adopting technology in business transition into CE process. Social innovation through the involvement of employees by sharing CE vision, synergizing and optimizing internal potential, and building up the green innovation culture has created an internal conducive climate to put CE principle into practice. Further result shows that a labor-intensive company’s business strategy prioritizes employment and job security over maximizing profits, which directly leads to the economic welfare and social protection of the business operation that makes an inclusive business.