Clinical/methodological problem: The identification of clinically significant prostate carcinomas while avoiding overdiagnosis of low-malignant tumors is a challenge in routine clinical practice. Standard radiologic procedures: Multiparametric magnetic resonance imaging (MRI) of the prostate acquired and interpreted according to PI-RADS (Prostate Imaging Reporting and Data System Guidelines) is accepted as a clinical standard among urologists and radiologists. Methodological innovations: The PI-RADS guidelines have been newly updated to version 2.1 and, in addition to more precise technical requirements, include individual changes in lesion assessment. Performance: The PI-RADS guidelines have become crucial in the standardization of multiparametric MRI of the prostate and provide templates for structured reporting, facilitating communication with the referring physician. Evaluation: The guidelines, now updated to version 2.1, represent a refinement of the widely used version 2.0. Many aspects of reporting have been clarified, but some previously known limitations remain and require further improvement of the guidelines in future versions.

Amyloidosis is a systemic disorder produced by the deposition of insoluble protein fibrils that fold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality than patients without cardiac involvement. The two most prevalent forms of amyloidosis associated with cardiac involvement are AL amyloidosis, due to the deposition of immunoglobulin light chains, and ATTR amyloidosis, due to the deposition of the transthyretin (TTR) protein in mutated or senile form. This article aims to review the different cardiac imaging modalities (echocardiography, cardiac magnetic resonance imaging, nuclear medicine and tomography) that allow to determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, we suggest a diagnostic algorithm to determine cardiac involvement in amyloidosis adapted to locally available diagnostic tools, with a practical and clinical approach.

With the increasing demand for sustainable energy, advanced characterization methods are becoming more and more important in the field of energy materials research. With the help of X-ray imaging technology, we can obtain the morphology, structure and stress change information of energy materials in real time from two-dimensional and three-dimensional perspectives. In addition, with the help of high penetration X-ray and high brightness synchrotron radiation source, in-situ experiments are designed to obtain the qualitative and quantitative change information of samples during the charge and discharge process. In this paper, X-ray imaging technology based on synchrotron and its related applications are reviewed. The applications of several main X-ray imaging technologies in the field of energy materials, including X-ray projection imaging, transmission X-ray microscopy, scanning transmission X-ray microscopy, X-ray fluorescence microscopy and coherent diffraction imaging, are discussed. The application prospects and development directions of X-ray imaging in the future are prospected.

Introduction: Periodontal disease affects more than half of the population in Colombia and is estimated to be one of the leading causes of oral morbidity. Diagnostic aids that allow the evaluation of its extension and severity are of importance since this will provide reliable tools to quantify the severity of the problem. Objective: To determine the inter-examiner agreement for the detection of radiographic findings in patients with localized chronic periodontitis using conventional periapical radiography. Methods: Study of diagnostic tests including patients with localized chronic periodontitis, the tooth with the worst clinical insertion level and a single conventional radiograph per dental organ using parallelism technique. The radiographic evaluations were performed by two independent and blinded evaluators for the findings: lamina dura, bone defects and type of defect. The agreement obtained was estimated through Cohen’s Kappa. Results: A total of 125 radiographs were taken. The mean age was 38.8 ± 9.9, and 61.6% were women. Concordance for lamina dura was 0.08 (95% CI: -0.04–0.21), bone defects 1.00 (95% CI: 1.00–1.00); type of defect present 0.31 (95% CI: 0.29–0.38). Conclusions: Concordance was evaluated as null, almost perfect and acceptable for the findings lamina dura, presence of bone defects and type of defect respectively. For some findings and given the importance of the diagnostic and therapeutic processes, more accurate evaluations are needed which would result in a higher degree of agreement.

Currently there is a great acceptance in medicine and dentistry that clinical practice should be “evidence-based” as much as possible. That is why multiple works have been published aimed at decreasing radiation doses in the different types of imaging modalities used in dentistry, since the greater effect of radiation, especially in children, forces us to take necessary measures to rationalize its use, especially with Cone Beam computed tomography (CBCT), the method that provides the highest doses in dentistry. This review was written using such an approach with the purpose of rationalizing the radiation dose in our patients. In order to formulate recommendations that contribute to the optimization of the use of ionizing radiation in dentistry, the SEDENTEXCT project team compiled and analyzed relevant publications in the literature, guidelines that have demonstrated their efficiency in the past, thus helping to see with different perspectives the dose received by patients, and with this, it is recommended taking into account this document so as to prescribe more adequately the complementary examinations that we use on a daily basis.

Magnetite magnetic nanoparticles (MNP) exhibit superparamagnetic behavior, which gives them important properties such as low coercive field, easy superficial modification and acceptable magnetization levels. This makes them useful in separation techniques. However, few studies have experimented with the interactions of MNP with magnetic fields. Therefore, the aim of this research was to study the influence of an oscillating magnetic field (OMF) on polymeric monolithic columns with vinylated magnetic nanoparticles (VMNP) for capillary liquid chromatography (cLC). For this purpose, MNP were synthesized by coprecipitation of iron salts. The preparation of polymeric monolithic columns was performed by copolymerization and aggregation of VMNP. Taking advantage of the magnetic properties of MNP, the influence of parameters such as resonance frequency, intensity and exposure time of a OMF applied to the synthesized columns was studied. As a result, a better separation of a sample according to the measured parameters was obtained, so that a column resolution (R_s) of 1.35 was achieved. The morphological properties of the columns were evaluated by scanning electron microscopy (SEM). The results of the chromatographic properties revealed that the best separation of the alkylbenzenes sample occurs under conditions of 5.5 kHz and 10 min of exposure in the OMF. This study constitutes a first application in chromatographic separation techniques for future research in nanotechnology.