Subcutaneous (SC) drug delivery is one of the best routes of drug administration to patients over intravenous (IV) administration due to the ease of application and patient acceptance. The main limitation of using the SC route is administering larger volumes of drug, greater than 3–5 mL for therapeutic dosages. Wearable injectors on body devices are an attractive option for larger-volume drug delivery to patients. Thus, the need for a self-administration strategy at home is growing faster and is required for the next level of time-dependent and high-volume drug delivery. The advances in low-cost, connected on-body delivery systems hold great opportunity for novel ways of delivering home-based drug therapy in the future.

Flower-visiting insects may be pollinators or, conversely, unrelated to the reproductive process of plants. Interactions between pollinating and non-pollinating flower visitors can negatively influence pollen transfer. Little is known about the effects of bee visits on pollination of squash (Cucurbita spp.) flowers and their interactions with the presence of other floral visitors. The study was conducted at the Facultad de Ciencias Agrarias (Universidad Nacional de Rosario) in the south of Santa Fe (Argentina) and evaluated the effect of the presence of non-pollinating floral visitors on bee foraging in the flowers of two cultivated squash species. Flower sex and squash species C. maxima and C. moschata were included as variables. A total of 937 visitors were recorded in 403 flowers. Bees of the tribes Eucerini and Apini were the most abundant pollinators with an average of 2.3 individuals per flower during 10 minutes of observation. Diptera, flower sex and squash species did not influence the number of bee visits, whereas the prolonged stay of coleoptera and formicids negatively affected the presence of bees on both squash species. The presence of coleoptera reduced bee visits by 38%, while in the presence of ants, bees did not visit the flowers. The theft of nectar and pollen by non-pollinating floral visitors could have a negative effect on the reproductive success of squash.

Objective: To evaluate the clinical and radiographic results and complications of arthroscopic subcapital realignment osteotomy for the treatment of chronic and stable proximal femoral epiphysiolysis (PFE) in an initial series of patients. According to the literature review, the study presents the first description of an arthroscopic technique of this type of osteotomy. Methods: Between June 2012 and December 2014, seven patients underwent arthroscopic subcapital realignment osteotomy for the treatment of chronic, stable PFE. The mean age of the patients was 11 years and four months. Minimum follow-up ranged from 6 to 36 months (mean, 16.5 months). Patients were clinically evaluated according to the Harris Hip Score modified by Byrd and radiographically according to Southwick’s quantitative classification and the epiphyseal-diaphyseal angle. Postoperative complications were analyzed. Results: With regard to the evaluation of the Harris Hip Score Modified by Byrd clinical score, a preoperative mean of 35.8 points and a postoperative mean of 97.5 points were observed (p < 0.05). Radiographically, five patients were classified as Southwick grade II and two as grade III. A mean correction of the epiphyseal-diaphyseal angle of 40° was observed. There were no immediate postoperative complications. One patient developed avascular necrosis of the femoral head, without collapse or chondrolysis at the last follow-up (22 months). Conclusion: The arthroscopic technique presented by the authors for the treatment of chronic, stable PFE resulted in clinical and radiographic improvement of the patients in this initial series.

Bangladesh’s coastal regions are rich in saline water resources. The majority of these resources are still not being used to their full potential. In the southern Bangladeshi region of Patuakhali, research was conducted to investigate the effects of mulching and drip irrigation on tomato yield, quality, and blossom-end rot (BER) at different soil salinity thresholds. There were four distinct treatments applied: T₁= drip irrigation with polythene mulch, T₂ = drip irrigation with straw mulch, T₃ = drip irrigation without mulch, and T₄ = standard procedure. While soil salinity was much greater in treatment T₃ (1.19–8.42 dS/m) fallowed by T₄ (1.23–8.63 dS/m), T1 treatments had the lowest level of salinity and the highest moisture retention during every development stage of the crops, ranging from 1.28–4.29 dS/m. Treatment T₃ exhibited the highest soil salinity levels (ranging from 1.19 to 8.42 dS/m), followed by T₄ with a range of 1.23 to 8.63 dS/m. In contrast, T₁ treatments consistently maintained the lowest salinity levels (ranging from 1.28 to 4.29 dS/m) and the highest moisture retention throughout all stages of crop development. In terms of yield, drip irrigation with no mulch treatment (T₃) provided the lowest output (13.37 t/ha), whereas polyethylene mulching treatment (T₁) produced the maximum yield (46.04 t/ha). According to the study, conserving moisture in tomato fields and reducing soil salinity may both be achieved with drip irrigation combined with polythene mulch. The research suggests that employing drip irrigation in conjunction with polythene mulch could effectively preserve moisture in tomato fields and concurrently decrease soil salinity.

With the rapid development of the times, modern educational technology and traditional teaching mode have produced a more effective online + offline hybrid teaching mode in teachers' exploration and innovation. Through this hybrid mode of college English teaching, to a large extent, it can expand the actual classroom, and also enable students to fully carry out English learning outside the classroom, which has a very significant positive effect on college Students' English learning and the construction of college classroom.

In the great practice of long-term revolution, construction and reform, the red gene created and developed by the CPC is a noble belief and noble emotion that has been continuously precipitated and inherited in the blood and struggle of countless people throughout the country, and has been deeply rooted in the blood and soul of the people of the CPC. Against the backdrop of the continuous development of modern education, integrating the red gene into the daily ideological and political education work of college students requires a clear understanding of its practical significance, and establishing the basic principle of integration based on the red gene, further promoting reform and innovation in inheriting and promoting the red gene in universities, and comprehensively enhancing the ideological and political awareness of college students, Provide a strong talent force for China's socialist construction.