Endosulfan (6,7,8,9,10,10-Hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine-3-oxide) is an off-patent insecticide used in agricultural farms. Its usage as a pesticide has become highly controversial over the last few decades. This is due to its reported hazardous nature to health and side effects like growth retardation, hydrocephalus, and undesired changes in the male and female hormones leading to complications in sexual maturity. Endosulfan is the main culprit among all pesticide poisoning incidents around the world. Though the usage of this dreaded pesticide is banned by most countries, the high stability of this molecule to withstand degradation for a long period poses a threat to mankind even today. So, it has become highly essential to detect the presence of this poisonous pesticide in the drinking water and milk around these places. It is also advisable to check the presence of this toxic material in the blood of the population living in and around these places so that an early and appropriate management strategy can be adopted. With this aim, we have developed a sensor for endosulfan that displayed high selectivity and sensitivity among all other common analytes in water and biological samples, with a wide linear concentration range (2 fM to 2 mM), a low detection limit (2 fM), and rapid response. A citrate-functionalized cadmium-selenium quantum dot was used for this purpose, which showed a concentration-dependent fluorescence enhancement, enabling easy and sensitive sensing. This sensor was utilized to detect endosulfan in different sources of water, human blood serum, and milk samples with good recoveries. It is also noted that the quantum dot forms a stable complex with endosulfan and is easy to separate from the contaminated source, paving the way for purifying the contaminated water. More detailed tests and validation of the sensor are needed to confirm these observations.
In the present work, a series of butyl methacrylate/1-hexene copolymers were synthesized, and their efficiency as viscosity index improvers, pour point depressants, and shear stabilizers of lube oil was investigated. The effect of 1-hexene molar ratio, type, and concentration of Lewis acids on the incorporation of 1-hexene into the copolymer backbone was investigated. The successful synthesis of the copolymers was confirmed through FTIR and 1H NMR spectroscopy. Results obtained from quantitative 1H NMR and GPC revealed that an increase in the molar ratio of 1-hexene to butyl methacrylate, along with concentration of Lewis acids led to an increase in 1-hexene incorporation and a reduction in Mn and Ð. Similar trends were observed when the Lewis acid changed from AlCl3 to organometallic acids. The maximum 1-hexene incorporation (26.4%) was achieved for sample BHY3, with a [1-hexene/BMA] ratio of 4 mol% and a [Yb(OTf)3/BMA] ratio of 2.5 mol%. Evaluation of the synthesized copolymers as lube oil additives demonstrated that the viscosity index was more significantly influenced by samples with higher molecular weight. Sample BHA13 represents maximum VI of 137. The copolymer containing Yb(OTf)3 as a catalyst exhibited superior efficiency as a pour point depressant. Furthermore, sample BHY3 showed the lowest shear stability index (6.4).
In the history of public health, space has evolved through several stages driven by shifts in concepts of disease control. The history of public health is summarized by George Rosen in six phases: Origins (before 500 CE), Middle Ages (500–1500), Mercantilism and Absolutism (1500–1750), Enlightenment and Revolution (1750–1830), Industrialism and the Sanitary Movement (1830–1875), and the Bacteriological Era (1875–present). By integrating architectural sociology—a temporal lens examining the interplay between architecture, individuals, and society—this study investigates how architects historically responded to public health challenges, offering critical insights for contemporary healthy habitat design. Architecture not only addresses survival needs but also materializes societal consciousness. The progression of health-related cognition (e.g., germ theory), behavioural norms (e.g., hygiene practices), infrastructure systems (e.g., sanitation networks), and scientific advancements collectively redefined spatial paradigms. Architects constructed temples, thermae, lazarettos, Beitian Yangbingfang (charitable infirmaries), anatomical theaters, quarantine hospitals, tenements, mass housing, and biosafety laboratories. These cases exemplify the co-evolution of “Concept” (disease control ideologies), “Technology” (construction methods), and “Space” (built environments). By synthesizing centuries of public health spatial practices, this research deciphers the dynamic interplay among “Concept, Technology, and Space”. Leveraging historical patterns, we propose a predictive framework to refine future spatial strategies in anticipation of emerging health crises.
Targeted Poverty Alleviation refers to the targeted funding work completed in the process of higher education development. However, at present, in the process of implementing the requirements of Targeted Poverty Alleviation in China's universities, some students' families are difficult to complete identification, and there are also some problems in the information management of the funders, which has seriously affected the funding for students with financial difficulties in their families during the period of higher education in China. With the rapid development and progress of Big data technology, through the establishment of a sound information technology system, we must help students actively change the funding model in the future and greatly improve the funding, which is of great significance to the development of university funding supervision and management.
In the current context of new engineering, the teaching of the course "Civil Engineering Construction Organization and Management" should be targeted and focused. In terms of setting up the course content, schools need to engage in extensive communication and cooperation with enterprises and industry associations, and integrate more practical education elements into the teaching methods to ensure that students can achieve a unity of knowledge and action; In relevant course teaching, teachers should also introduce more ideological and political elements to improve students' ideological and moral literacy. This article analyzes and explores the teaching reform of the course "Civil Engineering Construction Organization and Management" in the context of the new engineering discipline.
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