Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.
In recent years, ghost imaging has made important progress in the field of remote sensing imaging. In order to promote the application of solar ghost imaging in this field, this paper studies the computational ghost imaging based on the incoherent light of blackbody radiation. Firstly, according to the intensity probability density function of blackbody radiation, the expression of contrast-to-noise ratio (RCN) describing the quality of computational ghost imaging is obtained, and then the random speckle pattern simulating blackbody radiation is generated by computer with the idea of slice sampling, finally, a digital light projector is used to modulate and generate the random modulated light that simulates the blackbody radiation light source, and this light source is used to realize the computational ghost image of the reflective object in the experiment. The “ghost image” of the object under different measurement frame numbers is reconstructed, and the contrast-to-noise ratio describing the imaging quality is measured. The results show that the image quality is relatively good when the average intensity (gray) of the randomly modulated speckle is about 160. On the other hand, the contrast-to-noise ratio of the image gradually increases from 0.8795 to 1.241, 1.516, 1.755, 2.100 and 2.371 as the number of measurement frames increases from 2,000 to 4,000, 6,000, 8,000, 12,000 and 20,000, respectively. The experimental results are basically consistent with the theoretical analysis. The results are of great significance for the application of ghost imaging with incoherent light, such as sunlight, which is approximately regarded as blackbody radiation, in the field of remote imaging.
The focus of the article is the evaluation of the interaction between regional state bodies and business structures in Kazakhstan, specifically in terms of the development of public-private partnerships. The purpose of the research is to enhance the understanding of the theoretical and practical aspects of the mechanism of interaction between the state and business structures. Through an examination of the various structural components of the partnership development strategy, the study aims to identify the elements of the mechanism for the implementation of the state and business development strategy. Additionally, the research seeks to establish the correlation between the outcomes of the joint entrepreneurship mechanism and the criteria used to evaluate the performance of regional state bodies. To assess the effectiveness of the interaction between business and government at the regional level in Kazakhstan, a survey-based evaluation was conducted to measure the satisfaction levels of public utilities, entrepreneurs, and businesses with the activities of local authorities. The survey also evaluated the degree of corruption among local authorities. A matrix of interaction between business and government was created, and various models and algorithms for the interaction between government representatives and business structures were studied. The research findings highlight the importance of enhancing the collaboration between the state and the business sector, promoting the implementation of public-private partnerships, and establishing social partnerships to cultivate mutually beneficial relationships.
Nigeria’s palm oil processing industry poses significant environmental pollution risks, jeopardizing the country’s ability to meet the UN’s 17 Sustainable Development Goals (SDGs) by 2030. Traditional processing methods generate palm oil mill effluent (POME), contaminating soil and shallow wells. This study investigated water samples from five locations (Edo, Akwa-Ibom, Cross River, Delta, and Imo states) with high effluent release. While some parameters met international and national standards (WHO guidelines, ASCE, NIS, and NSDWQ) others exceeded acceptable limits, detrimental to improved water quality. Results showed, pH values within acceptable ranges (6.5–8.5), high total conductivity and salinity (800–1150 µS/cm), acceptable hardness values (200–300 mg/L), nitrite concentrations (10–45 mg/L), excessive magnesium absorption (> 50 mg/L), biochemical oxygen demand (BOD) indicating significant pollution (75–290 mg/L), total dissolved solids (TDS) exceeding safe limits in four locations, total solids (TS) exceeding allowable limits for drinking water (310–845 mg/L), water quality index (WQI) values ranged from “poor” to “very poor”. POME contamination by metals like magnesium, nitrite, chloride, and sodium compromised shallow well water quality. Correlation analysis confirmed robust results, indicating strong positive correlations between conductivity and TDS (r = 0.85, p < 0.01) and pH and total hardness (r = 0.65, p < 0.05). The study emphasizes the need for environmentally friendly palm oil processing methods to mitigate pollution, ensure safe drinking water, and achieve Nigeria’s SDGs. Implementation of sustainable practices is crucial to protect public health and the environment.
The structure, thermodynamic stability, ionization potential (IP) and electron affinity (EA) energy level difference (Eg) and tension of lowest unoccupied orbit (LUMO) and highest occupied orbit (HOMO) of armchair single wall carbon nanotubes (C-NTs), BN hybrid carbon nanotubes (BC2N-NTs) and all BN nanotubes (BN-NTs) were systematically studied with AM1 method in this paper. Calculation results show that when n value is constant, (n, n) C-NTs (n = 3,4,5,6) has the largest diameter and BN-NTs has the smallest diameter; (n, n) the values of Eg (HOMO-LUMO) and n of C-NTs and BC2N-NTs are related; POAV analysis shows that different hybrid atoms have different contributions to the hybrid mode of nanotube atoms and the tension of nanotubes.
Project success requires team commitment, which is a product of an encouraging culture of cooperation and teamwork among project team members. The research work aims to ascertain which components of team commitment affect the performance of construction projects in Nigeria. The research adopted a quantitative design where questionnaires were used for data collection. Out of 1233 questionnaires distributed, 975 were received with valid responses and used for data analysis. Data were analysed descriptively using percentage, mean score, and relative agreement index. The study showed the factors of team commitment having an effect on project performance, as rated by the respondents, to be: Normative component: “Project team members owe a great deal to this organisation”; “Members of the project team do not feel it is right to quit the project before completion”; “This organisation has a great deal of personal meaning for project team members”. Affective component: “This organisation deserves the loyalty of project team members”; “The project team considers the team’s problems as their own. Then, “One of the few negative consequences of leaving this organisation will be the scarcity of available alternatives” is for continuance. In conclusion, the emotional attachment of the team members and sense of obligation to the project team and construction organisation are the driving forces behind pushing for the successful outcome of projects within the Nigerian construction industry.
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