Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientific authorities. Along with positron emission tomography (PET)-18 fluorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.
In recent years, ghost imaging has made important progress in the field of remote sensing imaging. In order to promote the application of solar ghost imaging in this field, this paper studies the computational ghost imaging based on the incoherent light of blackbody radiation. Firstly, according to the intensity probability density function of blackbody radiation, the expression of contrast-to-noise ratio (RCN) describing the quality of computational ghost imaging is obtained, and then the random speckle pattern simulating blackbody radiation is generated by computer with the idea of slice sampling, finally, a digital light projector is used to modulate and generate the random modulated light that simulates the blackbody radiation light source, and this light source is used to realize the computational ghost image of the reflective object in the experiment. The “ghost image” of the object under different measurement frame numbers is reconstructed, and the contrast-to-noise ratio describing the imaging quality is measured. The results show that the image quality is relatively good when the average intensity (gray) of the randomly modulated speckle is about 160. On the other hand, the contrast-to-noise ratio of the image gradually increases from 0.8795 to 1.241, 1.516, 1.755, 2.100 and 2.371 as the number of measurement frames increases from 2,000 to 4,000, 6,000, 8,000, 12,000 and 20,000, respectively. The experimental results are basically consistent with the theoretical analysis. The results are of great significance for the application of ghost imaging with incoherent light, such as sunlight, which is approximately regarded as blackbody radiation, in the field of remote imaging.
The Method of Discretization in Time (MDT) is a hybrid numerical technique intended to alleviate upfront the computational procedure of timedependent partial differential equations of parabolic type upfront. The MDT engenders a sequence of adjoint second order ordinary differential equations, wherein the space coordinate is the independent variable and time becomes an embedded parameter. Essentially, the adjoint second order ordinary differential equations are considered of “quasistationary” nature. In this work, the MDT is used for the analysis of unsteady heat conduction in regular bodies (large wall, long cylinder and sphere) accounting for nearly constant thermophysical properties, uniform initial temperature and surface heat flux. In engineering applications, the surface heat flux is customarily provided by electrical heating, radiative heating and pool fire heating. It is demonstrated that the approximate, semianalytical temperature solutions of the first adjoint “quasistationary” heat conduction equations using the first time jump are easily obtainable for each regular body. For enhanced acccuracy, regression analysis is applied to the deviations of the dimensionless surface temperature as a function of the dimensionless time for each regular body.
This study offers a focused examination on Xinfang system, China’s unique mechanism particularly on its ability and efficacy in mediating land disputes between farmers and governmental bodies for social governance purposes. Based on interviews with 10 farmers, the study elucidates the system has low entry barriers and user-friendly, thus fast becoming the preferred system option when dealing with land conflicts. Xinfang facilitates direct communication between farmers and government officials, thereby in line with the sociocultural conventions of the rural populace. The study also highlights several constraints. While the Xinfang system employs a multifaceted approach to conflict resolution, including negotiation and grassroots governmental intervention, it lacks legislative power and institutional authority that are required for effective management of more complex or multi-stakeholder land disputes. The study advocates for a comprehensive reassessment and subsequent reform of the Xinfang system, focusing particularly on its mechanisms and procedures for dispute resolution. Such reforms are not merely instrumental for the more robust safeguarding of farmers’ land rights, but also for enhancing the overall integrity and public trust in China’s legal and administrative frameworks.
Project success requires team commitment, which is a product of an encouraging culture of cooperation and teamwork among project team members. The research work aims to ascertain which components of team commitment affect the performance of construction projects in Nigeria. The research adopted a quantitative design where questionnaires were used for data collection. Out of 1233 questionnaires distributed, 975 were received with valid responses and used for data analysis. Data were analysed descriptively using percentage, mean score, and relative agreement index. The study showed the factors of team commitment having an effect on project performance, as rated by the respondents, to be: Normative component: “Project team members owe a great deal to this organisation”; “Members of the project team do not feel it is right to quit the project before completion”; “This organisation has a great deal of personal meaning for project team members”. Affective component: “This organisation deserves the loyalty of project team members”; “The project team considers the team’s problems as their own. Then, “One of the few negative consequences of leaving this organisation will be the scarcity of available alternatives” is for continuance. In conclusion, the emotional attachment of the team members and sense of obligation to the project team and construction organisation are the driving forces behind pushing for the successful outcome of projects within the Nigerian construction industry.
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