Gout is an arthritis characterized by the deposition of sodium monoacid crystals in the synovial membrane, articular cartilage, and periarticular tissues that leads to an inflamatory process. In most cases, the diagnosis is established by clinical criteria and analysis of the synovial fluid for MSU crystals. However, gout may manifest in atypical ways and make diagnosis difficult. In these situations, imaging studies play a fundamental role in helping to confirm the diagnosis or even exclude other differential diagnoses. Conventional radiography is still the most commonly used method in the follow-up of these patients, but it is a very insensitive test, because it only detects late changes. In recent years, advances in imaging methods have emerged in relation to gout. Ultrasound has proven to be a highly accurate test in the diagnosis of gout, identifying MSU deposits in articular cartilage and periarticular tissues, and detecting and characterizing tophi, tendinopathies, and tophi enthesopathies. Computed tomography is an excellent exam for the detection of bone erosions and evaluation of spinal involvement. Dual-energy computed tomography, a new method that provides information on the chemical composition of tissues, allows identification of MSU deposits with high accuracy. MRI can be useful in the evaluation of deep tissues not accessible by ultrasound. In addition to diagnosis, with the emergence of drugs that aim to reduce the tophaceous burden, imaging examinations become a useful tool in the follow-up treatment of gout patients.
In Costa Rica, there is no explicit recommendation from the competent authorities for the use of a specific phantom, so experts must explore what suppliers offer, among which the Normi Mam Digital phantom from PTW stands out. This article presents the results of the dosimetry and image quality control applied to the Normi Mam Digital phantom to validate it as equipment that complies with the recommendations of the Human Health Series No. 17. The results obtained were satisfactory, proving that the equipment complies with the tolerances recommended by international health bodies.
Introduction: Given the heterogeneous nature and inherent complexity of forensic medical expertise, the expert (medical professional or related areas) must make the best use of the technical and technological tools at his disposal. Imaging, referring to the set of techniques that allow obtaining images of the human body for clinical or scientific purposes, in any of its techniques, is a powerful support tool for establishing facts or technical evidence in the legal field. Objective: To analyze the use of magnetic resonance and computed tomography in postmortem diagnosis. Methodology: information was searched in the databases PubMed, Science Direct, Springer Journal and in the search engine Google Scholar, using the terms “X-Ray Computed Tomography”, “Magnetic Resonance Spectroscopy”, “Autopsy” and “Forensic Medicine” published in the period 2008–2015. Results: MRI is useful for the detailed study of soft tissues and organs, while computed tomography allows the identification of fractures, calcifications, implants and trauma. Conclusions: In the reports found in the literature search, regarding the use of nuclear magnetic resonance and computed tomography in postmortem cases, named by the genesis of the trauma, correlation was found between the use of imaging and the correct expert diagnosis at autopsy.
Based on the characteristics of liquid lens sparse aperture imaging, a radiative multiplet array structure is proposed; a simplified model of sparse aperture imaging is given, and the analytical expression of the modulation transfer function is derived from the optical pupil function of the multiplet array structure; the specific distribution form of this multiplet array structure is given, and the structure parameters are approximated by the dimensionless method; the two types of radiative multiplet array structures are discussed, and the filling factor, redundancy, modulation transfer function and other characteristic parameters are calculated. The physical phenomena exhibited by the parametric scan are discussed, and the structural features and imaging characteristics of these two arrays are compared. The results show that the type-II structure with larger actual equivalent aperture and actual cutoff frequency and lower redundancy is selected when the average modulation transfer function and the IF characteristics of the modulation transfer function of the two structures are close to each other; the type-II structure has certain advantages in imaging; the conclusion is suitable for arbitrary enclosing circle size because the liquid lens-based multiplet array structure adopts dimensionless approximation parameters; compared with the composite toroidal structure, the radiative multiplet mirror structure has a larger actual cut-off frequency and actual equivalent aperture when the filling factor is the same.
Amyloidosis is a systemic disorder produced by the deposition of insoluble protein fibrils that fold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality than patients without cardiac involvement. The two most prevalent forms of amyloidosis associated with cardiac involvement are AL amyloidosis, due to the deposition of immunoglobulin light chains, and ATTR amyloidosis, due to the deposition of the transthyretin (TTR) protein in mutated or senile form. This article aims to review the different cardiac imaging modalities (echocardiography, cardiac magnetic resonance imaging, nuclear medicine and tomography) that allow to determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, we suggest a diagnostic algorithm to determine cardiac involvement in amyloidosis adapted to locally available diagnostic tools, with a practical and clinical approach.
In recent years, ghost imaging has made important progress in the field of remote sensing imaging. In order to promote the application of solar ghost imaging in this field, this paper studies the computational ghost imaging based on the incoherent light of blackbody radiation. Firstly, according to the intensity probability density function of blackbody radiation, the expression of contrast-to-noise ratio (RCN) describing the quality of computational ghost imaging is obtained, and then the random speckle pattern simulating blackbody radiation is generated by computer with the idea of slice sampling, finally, a digital light projector is used to modulate and generate the random modulated light that simulates the blackbody radiation light source, and this light source is used to realize the computational ghost image of the reflective object in the experiment. The “ghost image” of the object under different measurement frame numbers is reconstructed, and the contrast-to-noise ratio describing the imaging quality is measured. The results show that the image quality is relatively good when the average intensity (gray) of the randomly modulated speckle is about 160. On the other hand, the contrast-to-noise ratio of the image gradually increases from 0.8795 to 1.241, 1.516, 1.755, 2.100 and 2.371 as the number of measurement frames increases from 2,000 to 4,000, 6,000, 8,000, 12,000 and 20,000, respectively. The experimental results are basically consistent with the theoretical analysis. The results are of great significance for the application of ghost imaging with incoherent light, such as sunlight, which is approximately regarded as blackbody radiation, in the field of remote imaging.
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