Gold nanoparticles (AuNPs) have been known to possess exceptional electric, biochemical, and optical characteristics and are ‘the topic of discussion’ these days, especially relating to the field of biomedicine. Several plants, bacteria, and fungi have been utilized for the generation of AuNPs, besides other physical and chemical methods. While some studies have been reported with gold nanoparticles, less are aimed at fungi and its optimization factors. These parameters can allow us to design AuNPs of our choice depending on the use. The present review focuses on and inspects AuNPs with green synthesis through fungus optimization parameters followed by applications, aiming specifically at their antibacterial activity. Their antibacterial characteristics can open new doors for the pharmaceutical industry in the future.

Photocatalysis, an innovative technology, holds promise for addressing industrial pollution issues across aqueous solutions, surfaces, and gaseous effluents. The efficiency of photodegradation is notably influenced by light intensity and duration, underscoring the importance of optimizing these parameters. Furthermore, temperature and pH have a significant impact on pollutant speciation, surface chemistry, and reaction kinetics; therefore, process optimization must consider these factors. Photocatalytic degradation is an effective method for treating water in environmental remediation, providing a flexible and eco-friendly way to eliminate organic contaminants from wastewater. Selectivity in photocatalytic degradation is achieved by a multidisciplinary approach that includes reaction optimization, catalyst design, and profound awareness of chemical processes. To create efficient and environmentally responsible methods for pollution removal and environmental remediation, researchers are working to improve these components.

The application of optimization algorithms is crucial for analyzing oil and gas company portfolio and supporting decision-making. The paper investigates the process of optimizing a portfolio of oil and gas projects under economic uncertainty. The literature review explores the advantages of applying various optimizers to models that consider the mean and semi-standard deviations of stochastic multi-year cash flows and revenues. The methods and results of three different optimization algorithms are discussed: ranking and cutting algorithms, linear (Simplex) and evolutionary (genetic) algorithms. Functions of several key performance indicators were used to test these algorithms. The results confirmed that multi-objective optimization algorithms that examine various key performance indicators are used for efficient optimization in oil and gas companies. This paper proposes a multi-criteria optimization model for investment portfolios of oil and gas projects. The model considers the specific features of these projects and is based on the Markowitz portfolio theory and methodological recommendations for project assessment. An example of its practical application to oil and gas projects is also provided.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.

Cyber-physical Systems (CPS) have revolutionized urban transportation worldwide, but their implementation in developing countries faces significant challenges, including infrastructure modernization, resource constraints, and varying internet accessibility. This paper proposes a methodological framework for optimizing the implementation of Cyber-Physical Urban Mobility Systems (CPUMS) tailored to improve the quality of life in developing countries. Central to this framework is the Dependency Structure Matrix (DSM) approach, augmented with advanced artificial intelligence techniques. The DSM facilitates the visualization and integration of CPUMS components, while statistical and multivariate analysis tool such as Principal Component Analysis (PCA) and artificial intelligence methods such as K-means clustering enhance complex system the analysis and optimization of complex system decisions. These techniques enable engineers and urban planners to design modular and integrated CPUMS components that are crucial for efficient, and sustainable urban mobility solutions. The interdisciplinary approach addresses local challenges and streamlines the design process, fostering economic development and technological innovation. Using DSM and advanced artificial intelligence, this research aims to optimize CPS-based urban mobility solutions, by identifying critical outliers for targeted management and system optimization.