Clinical/methodological problem: The identification of clinically significant prostate carcinomas while avoiding overdiagnosis of low-malignant tumors is a challenge in routine clinical practice. Standard radiologic procedures: Multiparametric magnetic resonance imaging (MRI) of the prostate acquired and interpreted according to PI-RADS (Prostate Imaging Reporting and Data System Guidelines) is accepted as a clinical standard among urologists and radiologists. Methodological innovations: The PI-RADS guidelines have been newly updated to version 2.1 and, in addition to more precise technical requirements, include individual changes in lesion assessment. Performance: The PI-RADS guidelines have become crucial in the standardization of multiparametric MRI of the prostate and provide templates for structured reporting, facilitating communication with the referring physician. Evaluation: The guidelines, now updated to version 2.1, represent a refinement of the widely used version 2.0. Many aspects of reporting have been clarified, but some previously known limitations remain and require further improvement of the guidelines in future versions.
The human brain has been described as a complex system. Its study by means of neurophysiological signals has revealed the presence of linear and nonlinear interactions. In this context, entropy metrics have been used to uncover brain behavior in the presence and absence of neurological disturbances. Entropy mapping is of great interest for the study of progressive neurodegenerative diseases such as Alzheimer’s disease. The aim of this study was to characterize the dynamics of brain oscillations in such disease by means of entropy and amplitude of low frequency oscillations from Bold signals of the default network and the executive control network in Alzheimer’s patients and healthy individuals, using a database extracted from the Open Access Imaging Studies series. The results revealed higher discriminative power of entropy by permutations compared to low-frequency fluctuation amplitude and fractional amplitude of low-frequency fluctuations. Increased entropy by permutations was obtained in regions of the default network and the executive control network in patients. The posterior cingulate cortex and the precuneus showed differential characteristics when assessing entropy by permutations in both groups. There were no findings when correlating metrics with clinical scales. The results demonstrated that entropy by permutations allows characterizing brain function in Alzheimer’s patients, and also reveals information about nonlinear interactions complementary to the characteristics obtained by calculating the amplitude of low frequency oscillations.
Vascular access in hemodialysis is one of the pillars of success of the program. Therefore, efforts should be directed firstly to achieve the greatest number of vascular accesses of the arteriovenous fistula type, and secondly to reduce complications related to access cannulation in order to functionally preserve the access. Several strategies have been described to improve this last aspect; this article describes the use of ultrasound to improve the probability of successful cannulation in cases considered difficult by the nursing team.
Amyloidosis is a systemic disorder produced by the deposition of insoluble protein fibrils that fold and deposit in the myocardium. Patients with amyloidosis and cardiac involvement have higher mortality than patients without cardiac involvement. The two most prevalent forms of amyloidosis associated with cardiac involvement are AL amyloidosis, due to the deposition of immunoglobulin light chains, and ATTR amyloidosis, due to the deposition of the transthyretin (TTR) protein in mutated or senile form. This article aims to review the different cardiac imaging modalities (echocardiography, cardiac magnetic resonance imaging, nuclear medicine and tomography) that allow to determine the severity of cardiac involvement in patients with amyloidosis, the type of amyloidosis and its prognosis. Finally, we suggest a diagnostic algorithm to determine cardiac involvement in amyloidosis adapted to locally available diagnostic tools, with a practical and clinical approach.
In recent years, ghost imaging has made important progress in the field of remote sensing imaging. In order to promote the application of solar ghost imaging in this field, this paper studies the computational ghost imaging based on the incoherent light of blackbody radiation. Firstly, according to the intensity probability density function of blackbody radiation, the expression of contrast-to-noise ratio (RCN) describing the quality of computational ghost imaging is obtained, and then the random speckle pattern simulating blackbody radiation is generated by computer with the idea of slice sampling, finally, a digital light projector is used to modulate and generate the random modulated light that simulates the blackbody radiation light source, and this light source is used to realize the computational ghost image of the reflective object in the experiment. The “ghost image” of the object under different measurement frame numbers is reconstructed, and the contrast-to-noise ratio describing the imaging quality is measured. The results show that the image quality is relatively good when the average intensity (gray) of the randomly modulated speckle is about 160. On the other hand, the contrast-to-noise ratio of the image gradually increases from 0.8795 to 1.241, 1.516, 1.755, 2.100 and 2.371 as the number of measurement frames increases from 2,000 to 4,000, 6,000, 8,000, 12,000 and 20,000, respectively. The experimental results are basically consistent with the theoretical analysis. The results are of great significance for the application of ghost imaging with incoherent light, such as sunlight, which is approximately regarded as blackbody radiation, in the field of remote imaging.
With the increasing demand for sustainable energy, advanced characterization methods are becoming more and more important in the field of energy materials research. With the help of X-ray imaging technology, we can obtain the morphology, structure and stress change information of energy materials in real time from two-dimensional and three-dimensional perspectives. In addition, with the help of high penetration X-ray and high brightness synchrotron radiation source, in-situ experiments are designed to obtain the qualitative and quantitative change information of samples during the charge and discharge process. In this paper, X-ray imaging technology based on synchrotron and its related applications are reviewed. The applications of several main X-ray imaging technologies in the field of energy materials, including X-ray projection imaging, transmission X-ray microscopy, scanning transmission X-ray microscopy, X-ray fluorescence microscopy and coherent diffraction imaging, are discussed. The application prospects and development directions of X-ray imaging in the future are prospected.
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