Accurate drug-drug interaction (DDI) prediction is essential to prevent adverse effects, especially with the increased use of multiple medications during the COVID-19 pandemic. Traditional machine learning methods often miss the complex relationships necessary for effective DDI prediction. This study introduces a deep learning-based classification framework to assess adverse effects from interactions between Fluvoxamine and Curcumin. Our model integrates a wide range of drug-related data (e.g., molecular structures, targets, side effects) and synthesizes them into high-level features through a specialized deep neural network (DNN). This approach significantly outperforms traditional classifiers in accuracy, precision, recall, and F1-score. Additionally, our framework enables real-time DDI monitoring, which is particularly valuable in COVID-19 patient care. The model’s success in accurately predicting adverse effects demonstrates the potential of deep learning to enhance drug safety and support personalized medicine, paving the way for safer, data-driven treatment strategies.
In the context of digital transformation, Chinese small and medium sized enterprises (SMEs) face significant challenges and opportunities in adapting to market dynamics and technological advancements. This study investigates the impact of coopetition strategy on the core competencies of SMEs, with a particular focus on marketing, technological, and integrative competencies. Data were collected from a sample of 300 SMEs in Anhui Province through an online survey, and reliability and validity were tested using SPSS and AMOS. The results indicate that dependency and trust significantly enhance the effectiveness of coopetition strategy from an external perspective, while managerial ambidexterity and strategic intent are critical internal factors driving the successful implementation of coopetition strategies. Both external and internal factors positively impact the core competencies of SMEs. Additionally, environmental uncertainty moderates the relationship between coopetition strategy and core competencies, underscoring the need for flexibility and adaptability in dynamic market environments. The findings suggest that SMEs can better integrate internal and external resources, optimize resource allocation, and improve operational efficiency through coopetition strategy, thereby enhancing their core competencies. This study provides valuable insights and practical guidance for policymakers and business practitioners aiming to support the digital transformation of SMEs.
Digitalization has recently gained significant relevance in the education field. The focus has been on its use and application, as well as on training teachers and students to become responsible, competent, and ethical users of technology. This is connected to the creation of policies and programs that promote online learning and interaction from basic to higher education. In this context, this study aims to analyze the scientific production related to digital citizenship through a bibliometric mapping of publications indexed in the Web of Science database. The goal is to identify the main research trends in this field. The results show a growth in the number of publications since 2016, mainly focusing on topics such as digital citizenship media, digital competences, higher education, teachers, students, adolescents, adults, competence, digital literacy, and citizenship education. The presence of a significant number of journals related to the field of education denotes a close relationship between this field and the topic of study. Also, it is revealing a higher concentration of research production in the United States and Europe, with Latin America being absent from this scenario. The study identifies an intellectual structure of the discipline, particularly regarding the most relevant authors, journals, and descriptors. These results are important for understanding the research practices inherent to the field, which projects digital citizenship as an emerging topic. The study concludes by proposing lines of interest for further research on the topic in education and other fields, as well as acknowledging the limitations found in the present article.
Business ethics plays a crucial role in developing modern business and the entire society. Thus, to develop the conceptual framework of business ethics, it is extremely interesting to study the concepts connected with it. The article identifies the main terms and concepts associated with business ethics. On this basis, the authors’ conceptual framework of business ethics was created. Within this conceptual framework, it is shown that each business unit builds and maintains relationships with stakeholders within two “circles of business ethics”: the inner circle of business ethics and the outer circle of business ethics. The article proves the hypothesis that business ethics should be considered in the context of relationships with all stakeholders, i.e., it is the ethics of business relationships with partners and competitors in the external environment, as well as within the internal environment (primarily with employees). The article will be of interest to specialists in the field of management, and corporate governance, as well as for anyone interested in the problems of corporate social management.
This study aims to explore the feasibility of using virtual reality technology to educate students with learning difficulties in the Asir region. To achieve the study aims, the researcher employed a descriptive design and deployed a quantitative technique, depending on the questionnaire as the main instrument for data collection. The research was carried out on a cohort of 240 educators hailing from the Asir region who were enlisted through a process of random sampling. The results of this study show that factors like infrastructure, human resources, administrative regulation, and student population have an impact on the use of virtual reality technology. The results suggest that there are no statistically significant differences in the development of using virtual reality technology among teachers of students with learning disabilities in the Asir region when taking into account factors such as experience and level of qualification.
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