Protein- and peptide-based medications are recognized for their effectiveness and lower toxicity compared to chemical-based drugs, making them promising therapeutic agents. However, their application has been limited by numerous delivery challenges. Polymeric nanostructures have emerged as effective tools for protein delivery due to their versatility and customizability. Polymers’ inherent adaptability makes them ideal for meeting the specific demands of protein-delivery systems. Various strategies have been employed, such as enzyme inhibitors, absorption enhancers, mucoadhesive polymers, and chemical modifications of proteins or peptides. This study explores the hurdles associated with protein and peptide transport, the use of polymeric nanocarriers (both natural and synthetic) to overcome these challenges, and the techniques for fabricating and characterizing nanoparticles.

This paper assesses South Africa’s massive infrastructure drive to revive growth and increase employment. After years of stagnant growth, this is now facing a deep economic crisis, exacerbated by the COVID-19 pandemic. This drive also comes after years of weak infrastructure investment, widening the infrastructure deficit. The plan outlines a R1 trillion investment drive, primarily from the private sector through the Infrastructure Fund over the next 10 years (Government of South Africa, 2020). This paper argues that while infrastructure development in South Africa is much-needed, the emphasis on de-risking for private sector buy-in overshadows the key role the state must play in leading on structurally transforming the economy.

Quantum dot can be seen as an amazing nanotechnological discovery, including inorganic semiconducting nanodots as well as carbon nanodots, like graphene quantum dots. Unlike pristine graphene nanosheet having two dimensional nanostructure, graphene quantum dot is a zero dimensional nanoentity having superior aspect ratio, surface properties, edge effects, and quantum confinement characters. To enhance valuable physical properties and potential prospects of graphene quantum dots, various high-performance nanocomposite nanostructures have been developed using polymeric matrices. In this concern, noteworthy combinations of graphene quantum dots have been reported for a number of thermoplastic polymers, like polystyrene, polyurethane, poly(vinylidene fluoride), poly(methyl methacrylate), poly(vinyl alcohol), and so on. Due to nanostructural compatibility, dispersal, and interfacial aspects, thermoplastics/graphene quantum dot nanocomposites depicted unique microstructure and technically reliable electrical/thermal conductivity, mechanical/heat strength, and countless other physical properties. Precisely speaking, thermoplastic polymer/graphene quantum dot nanocomposites have been reported in the literature for momentous applications in electromagnetic interference shielding, memory devices, florescent diodes, solar cells photocatalysts for environmental remediation, florescent sensors, antibacterial, and bioimaging. To the point, this review article offers an all inclusive and valuable literature compilation of thermoplastic polymer/graphene quantum dot nanocomposites (including design, property, and applied aspects) for field scientists/researchers to carry out future investigations on further novel designs and valued property-performance attributes.

The soundscape studied has gained increasingly frequent attention across multiple disciplines, especially in tourism and leisure domain. While it has already indicated a unique soundscape provides dynamic and memorable tourism experiences, a clearly mapped perspective across different segmentations of soundscapes, both natural and acoustically created, remains missing. Therefore, a comprehensive mapping and review of soundscape studies is imperative to understand its implications for potential inbound tourism research in future. This article aimed to explore potential soundscape studies by assessing trends and developments in recent decades (2013–2023). We applied a bibliometric approach, using a PRISMA framework and under NVivo 12 Plus, VOSViewer, and Biblioshiny-R-Studio software as analytical tools. Significant yield discoveries showed that tourism soundscape research is undergoing steady growth, as evidenced by quantity of publications and citation trends. Single and multi-country international collaborations characterized by soundscape outreach research playing an influential role were highlighted. We identified multiple research themes, such as anthropogenic noise and music heritage, and pointed out how we approached this research from two perspectives: environmental/natural and manufacturing/acoustics. In our review, several keywords and predominant themes were identified, which suggested soundscape studies have recently become an increasingly popular topic in tourism research. The broad spectrum of key themes, such a tourism, tourists, sustainability, areas, and development perspectives, are evidence points of significant diversity in these topics. Most importantly, our research offers significant theoretical and conceptual implications for future direction of soundscape studies. We identified three originality main focus domains in soundscape tourism research: urban and natural environments, technological advancements, and tourists’ perceptions and behaviors.

Tomato (Solanum lycopersicon L.) is a highly valued crop in the world, particularly in Nigeria with high nutritional and economic benefits. However, its production in Iwollo, Southeast Nigeria, is constrained by unfavorable weather conditions. To address this, a study was conducted at the Teaching and Research Farm, Department of Horticultural Technology, Enugu State Polytechnic, Iwollo, Southeast Nigeria to evaluate and select the best cultivar for high tunnel production using the Rank Summation Index. Completely Randomized Design with three replications was used, and six high-yielding cultivars, namely Roma VF, BHN-1021, Supremo, Pomodro, Money maker, and Iwollo local, were evaluated. Data were collected on key agronomic characters and analyzed with Analysis of Variance (ANOVA) at a 0.05 level of probability. There were significant differences in the number of leaves per plant, plant height, number of branches per plant, days to fruit maturity, fresh fruit weight, number of harvested fresh fruits per plant, and fresh fruit yield per plant among the cultivars. These characters that showed significant differences were ranked and summed up to obtain the Rank Summation Index (RSI) score. The results revealed that the Supremo cultivar had the lowest and best score (18). This suggests Supremo as the best cultivar for high tunnel tomato production in the study area, based on its superior performance across key agronomic traits.

On the basis of the enlightenment of international engineering education accreditation for the reform and development of higher education in China, combined with the important measures of the national “double first-class” construction, new challenges have been proposed for innovative talent cultivation among engineering majors in the context of promoting national development. These challenges also promote the reform of science-oriented courses among engineering majors. As a core mandatory course for engineering majors, biochemistry plays a crucial role in the entire educational process at universities, serving as a bridge between basic and specialized courses. To address challenges such as limited course resources, insufficient development of students’ advanced thinking and innovation skills, and overly standardized assessment methods, the bioengineering major from Guilin University of Technology restructured the biochemistry course content. A blended teaching model termed “three integrations, three stages, one sharing”, was implemented. This effort has yielded significant results, providing a research foundation for constructing an innovative talent cultivation system that is oriented toward industry needs within modern industrial colleges. It also offers valuable insights into and reference points for the cultivation of engineering talents and curriculum reform in local universities.