Zero-valent iron is a moderately reducing reagent that is both non-toxic and affordable. In the present work, iron nanoparticles were synthesized using bitter guard leaf extract (Momordica charantia L.) (BGL-Fe NP). Using leaf samples from bitter protectant extract, iron nanoparticles were synthesized with secondary metabolites such as flavonoids and polyphenols acting as capping and reducing agents. Polyphenols reduce Fe2+/Fe3+ to nanovalent iron or iron nanoparticles. Iron nanoparticles were synthesized by reducing iron chloride as a precursor with bitter protective leaf extract in an alkaline environment. The obtained BGL-Fe NPs were calcined for 4 h at various temperatures of 400 °C, 500 °C, and 600 °C. The obtained samples were coded as BGL-Fe NPs-4, BGL-Fe NPs-5, and BGL-Fe NPs-6, respectively. The synthesized BGL-Fe NPs were systematically characterized by XRD, SEM, FTIR, UV-Vis and TG-DTA analysis. The obtained BGL-Fe NPs were then used as an adsorbent to remove the aqueous solution of basic methylene blue (MB) dye. MB concentration was monitored using UV-Vis spectroscopy.
The rise of online gambling in Indonesia has emerged as a significant public health concern, driven by various psychological, social, and regulatory factors. Despite stringent laws prohibiting gambling, the accessibility and appeal of online platforms have led to increased participation, particularly among young adults. This phenomenon is characterized by a paradoxical sense of control that users feel while gambling online, which can lead to compulsive behaviors and addiction. The structural characteristics of online gambling platforms, including fast-paced games and easy accessibility, further exacerbate this issue. Social influences, particularly through social media and peer interactions, normalize gambling behaviors, making them more appealing to adolescents. Mental health issues, such as anxiety and depression, are closely linked to online gambling addiction, as individuals may use gambling as a coping mechanism. The COVID-19 pandemic has intensified these challenges, with many individuals turning to online gambling for entertainment during lockdowns. To address the growing prevalence of online gambling addiction, comprehensive regulatory frameworks are needed, alongside responsible gambling initiatives and public awareness campaigns. Collaboration among stakeholders, including government agencies, healthcare providers, and gambling operators, is crucial for effective intervention. Continuous monitoring and evaluation of online gambling trends will inform future policies and help identify emerging risks. By adopting a multifaceted approach, Indonesian policymakers and stakeholders can work towards minimizing the risks associated with online gambling and fostering a healthier environment for its citizens.
In our study, we examined 11 designated tourist destinations in Hungary, which can also be interpreted as tourism products including services, infrastructure and attractions. The National Tourism Development Strategy (NTS) also puts a strong emphasis on digitalisation, as it is an unstoppable process with a significant impact on tourism, thanks to globalisation, increasing competition, accelerating information flows and the dominant paradigm shifts on the demand and supply side. We used both qualitative and quantitative methods in our primary research. First, we conducted in-depth interviews with several important tourism service providers in Hungary on the topic of the digitalisation of tourism. A professional questionnaire, addressed to the offices responsible for destination management was distributed in the designated tourist destinations in Hungary in order to get a more comprehensive picture of the attitudes towards digitalisation in the regions under study. In the course of our work, we managed to classify the destinations into three distinctly different clusters. Our hypothesis—that the higher the digitalisation of a tourist destination is, the higher the average length of stay—was partially confirmed by calculating the regional value of the digitalisation, logistic regression analysis, slope and the individual factor categories.
Subcutaneous (SC) drug delivery is one of the best routes of drug administration to patients over intravenous (IV) administration due to the ease of application and patient acceptance. The main limitation of using the SC route is administering larger volumes of drug, greater than 3–5 mL for therapeutic dosages. Wearable injectors on body devices are an attractive option for larger-volume drug delivery to patients. Thus, the need for a self-administration strategy at home is growing faster and is required for the next level of time-dependent and high-volume drug delivery. The advances in low-cost, connected on-body delivery systems hold great opportunity for novel ways of delivering home-based drug therapy in the future.
This work presents the evaluation of iron oxide nanoparticles obtained from the aqueous extract of Eucalyptus grandis. Twenty-three experiments were carried out where the synthesis of nanoparticles was performed by using the aqueous extract together with salts of iron (II) chloride tetrahydrate and iron (III) chloride hexahydrate. A characterization was carried out by IR, TEM and BET, where bands were presented at 3,440.77, 1,559.26 and 445.31 cm−1, indicating the presence of iron oxide nanoparticles. A relatively high monodispersity was evidenced with particles around 9 nm. By means of BET analysis it was found to present a surface area of 131.897 m2/g. Obtaining nanoparticles by this green method presents yield values of 98%, with application in nanotechnology, biomedicine, environmental treatment, among others, making them highly versatile and their production cost is relatively low.
We investigate the impact on intertemporal distribution caused by a change of policy from tax to deficit financing of public investment, using a simple theoretical framework which combines the one-period McGuire-Olson economy with the conventional long-run Solow economy. This theoretical framework provides a simple way to highlight some significant interdependencies between private and public investments as well as the negative impact of taxation on aggregate productivity, and to trace some possible transmission mechanisms between deficit financing policies and the long-run path of consumption per head. The main tentative (theoretical) result is that although under fairly acceptable assumptions the likely impact of a deficit financing policy is to benefit the present at the expense of the future, under equally acceptable assumptions concerning the possibility of an excessive macro private saving–investment propensity, and/or of a significant productivity loss due to the excess burden of taxation, the adverse intertemporal distributional impact of deficit financing might become negligible, or even disappear altogether.
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