A logistics service company in Batam faces challenges related to warehouse load fulfillment and sorting inaccuracies. This study aims to identify proposed efficiency improvements to the goods distribution system using the cross-docking method. The research method chosen is cross-docking, a technique that eliminates the storage process in the warehouse, thus saving time and cost. The research findings show significant benefits, especially in achieving zero inventory efficiency. Data processing and discussion revealed that efficiencies were apparent by increasing the sorting tables from 1 to 6, with an output of 90,000 kg during aircraft loading and unloading (compared to approximately 77,000 kilograms). This efficiency arises from the larger output of the sorting tables compared to the input, eliminating the need for warehousing and adding ten trucks. As a result, the shipment can be completed in one trip, with no goods stored in the warehouse. The analysis shows that implementing cross-docking in the company increases efficiency in distributing goods to forwarding partners.

Rural sub-Saharan Africa faces limited medical access, healthcare worker shortages, and inadequate health information systems. Mobile health (mHealth) technologies offer potential solutions but remain underdeveloped in these settings. This review aims to explore the sociocultural context of mHealth adoption in rural sub-Saharan Africa to support sustainable implementation. A comprehensive Enhancing Transparency in Reporting the Synthesis of Qualitative Research (ENTREQ) search was conducted in databases like PubMed, MEDLINE, and African Journals Online, covering peer-reviewed literature from 2010 to 2024. Qualitative studies of mHealth interventions were included, with quality assessed via the Critical Appraisal Skills Program (CASP) checklist and data synthesized using a meta-ethnographic approach. Out of 892 studies, 38 met the inclusion criteria. Key findings include sociocultural factors like community trust influencing technology acceptance, local implementation strategies, user empowerment in health decisions, and innovative solutions for infrastructure issues. Challenges include privacy concerns, increased healthcare worker workload, and intervention sustainability. While mHealth can reduce healthcare barriers, success depends on sociocultural alignment and adaptability. Future interventions should prioritize community co-design, privacy protection, and sustainable, infrastructure-aware models.

A problem in post-harvest of avocado (Persea americana Mill.) is the heterogeneity in fruit ripening, due to differences in the time of fruit set and the inability to ripen on the tree, a situation that causes inconsistencies in quality and differences in the response to preservation and processing technologies. In postharvest, the application of ethylene gas in hermetic chambers has been used to advance ripening; however, the use of ethylene releasers in liquid form (ethephon) has been proposed as an alternative, mainly for the treatment of low volumes of fruit. The present work was carried out in the production zone of Salvador Escalante (Michoacán, Mexico) with the objective of evaluating the effect of the application of two concentrations of ethephon on the time and homogenization of fruit ripening of avocado cultivars (cv.) Hass and Méndez. Fruits with 23.4% (cv. Hass) and 24% (cv. Méndez) of dry matter were harvested; one group was immersed in a solution of ethephon 500 mg/L and the other in 1,000 mg/L, both for 5 minutes; the treated fruits plus a control were stored at 20 °C for 11 days. Changes in respiration, ethylene production, weight loss, firmness, epicarp and pulp color, total phenol, chlorophyll and total carotenoid concentrations were evaluated. The results showed that ethephon doses of 1,000 mg/L in cv. Hass and 500 mg/L in cv. Méndez presented a ripening process 2 days earlier than the control.

Background: Multiple sclerosis is often a longitudinal disease continuum with an initial relapsing-remitting phase (RRMS) and later secondary progression (SPMS). Most currently approved therapies are not sufficiently effective in SPMS. Early detection of SPMS conversion is therefore critical for therapy selection. Important decision-making tools may include testing of partial cognitive performance and magnetic resonance imaging (MRI). Aim of the work: To demonstrate the importance of cognitive testing and MRI for the prediction and detection of SPMS conversion. Elaboration of strategies for follow-up and therapy management in practice, especially in outpatient care. Material and methods: Review based on an unsystematic literature search. Results: Standardized cognitive testing can be helpful for early SPMS diagnosis and facilitate progression assessment. Annual use of sensitive screening tests such as Symbol Digit Modalities Test (SDMT) and Brief Visual Memory Test-Revised (BVMT-R) or the Brief International Cognitive Assessment for MS (BICAMS) test battery is recommended. Persistent inflammatory activity on MRI in the first three years of disease and the presence of cortical lesions are predictive of SPMS conversion. Standardized MRI monitoring for features of progressive MS can support clinically and neurocognitively based suspicion of SPMS. Discussion: Interdisciplinary care of MS patients by clinically skilled neurologists, supported by neuropsychological testing and MRI, has a high value for SPMS prediction and diagnosis. The latter allows early conversion to appropriate therapies, as SPMS requires different interventions than RRMS. After drug switching, clinical, neuropsychological, and imaging vigilance allows stringent monitoring for neuroinflammatory and degenerative activity as well as treatment complications.

This study critically examines the implications of international transport corridor projects for Central Asian countries, focusing on the Western-backed Transport Corridor Europe-Caucasus-Asia (TRACECA), the Chinese initiative “One Belt—One Road”, and the International North-South Transport Corridor (INSTC) supported by the Russian Federation, India, and Iran. The analysis underscores the risks associated with Western projects, highlighting a need for a more explicit commitment to substantial infrastructure investments and persistent contradictions among key investors and beneficiaries. While the Chinese initiative presents significant benefits such as transit participation, infrastructure development, and economic investments, it also carries risks, notably an increased debt burden and potential monopolization by Chinese corporations. The study emphasizes that Central Asian countries, though indirect beneficiaries of INSTC, may not be directly involved due to geographical constraints. Study findings advocate for Central Asian nations to balance foreign investments, promote economic integration, and safeguard political and economic sovereignty. The study underscores the region’s wealth of natural and human resources, emphasizing the potential for increased demand for goods and services with improved living standards, strategically positioning these countries in the evolving global economic landscape.