Constructed wetlands have emerged as a sustainable alternative for decentralized wastewater treatment in developing countries which face challenges with urbanization and deteriorating infrastructure. This paper discusses the key factors affecting the implementation of constructed wetlands in developing countries. A case study research design was adopted, which focused on Bulawayo, Zimbabwe. A mixed-method approach was adopted for the study. Spatial analysis was conducted to identify potential sites for constructed wetlands in the city of Bulawayo. Semi structured interviews were conducted, with relevant stakeholders, such as town planners, civil engineers, NGO representatives, community leaders, and quantity surveyors. The findings reveal that political reforms, public acceptance, land availability, and funding are crucial for the successful implementation of constructed wetlands. Additionally, four sites were identified as the most favorable preliminary locations for these systems. The paper captures all the key factors relevant to the implementation of constructed wetlands (CWs) with a closer look at policy and the role it plays in the adoption of decentralized wastewater treatment systems. Formulating policy around the decentralized sanitation systems was considered imperative to the success of the systems whether in implementation or in operation. The paper adds to knowledge in the subject of sustainable wastewater treatment alternatives for developing countries. However, further research can be conducted with a different methodology to ascertain the applicability of the systems in developing urban cities considering other important aspects in the implementation of wastewater treatment systems.

In the last several decades, cardiovascular diseases (CVDs) have emerged as a major hazard to human life and health. Conventional formulations for the treatment of CVD are available, but they are far from ideal because of poor water solubility, limited biological activity, non-targeting, and drug resistance. With the advancement of nanotechnology, a novel drug delivery approach for the treatment of CVDs has emerged: nano-drug delivery systems (NDDSs). NDDSs have shown significant advantages in tackling the difficulties listed above. Cytotoxicity is a difficulty with the use of non-destructive DNA sequences. NDDS categories and targeted tactics were outlined, as well as current research advancements in the diagnosis and treatment of CVDs. It’s possible that gene therapy might be included into nano-carriers in the delivery of cardiovascular medications in the future. In addition, the evaluation addressed the drug’s safety.

Depression is a mental disorder caused by various causes with significant and persistent depressed mood as the main clinical feature, and is the most common mental illness worldwide and in our country. The number of patients with depression worldwide was as high as 350 million in 2017, and the number of patients with depression in our country was nearly 100 million in 2019. The greatest danger of depression is self-injurious and suicidal behaviour, and this behaviour carries a high medical burden. Medication is the most costly treatment for depression in China, and while it is an effective way to treat patients with depression, it has many side effects and poor patient compliance. Non-pharmacological treatments commonly used in clinical practice include physiotherapy and psychotherapy. Physiotherapy is commonly used in non-convulsive electroconvulsive therapy, but its clinical efficacy is uncertain and it can also cause adverse effects such as heart failure and arrhythmias, which are poorly tolerated by patients. Psychotherapy is also a common non-pharmacological therapy. Cognitive therapy is a common form of psychotherapy, but the cycle of cognitive therapy is too long, the cost to the patient is high, and the patient’s cognitive ability has certain requirements. Music therapy is a combination of art and science. It is a cross-discipline that combines body, movement, dance and psychology and is a method of psychotherapy that has biological, psychological and social functions to compensate for deficiencies. Music therapy sees a fundamental connection between mind and body and emphasises that what affects the body also affects the mind. When mind-body integration is lacking, individuals will suffer from a variety of psychological disorders. Therefore, the core principles of music therapy emphasise that holistic individual health is embodied in the integration of mind and body, that body movement is expressive and communicative, and that music therapy uses body movement as a method of assessing the individual and as a means of clinical intervention.

Beta macrocarpa, Guss is an interesting species showing very low germination rates. The leading objectives of this work were to investigate the dormancy mechanism and to find methods to break dormancy in order to achieve rapid, uniform and high germination. Macro and micro-morphologic analyses were performed by stereo microscopy and scanning electron microscopy showed two fruit coats. The yellow external coat or persistent perianth coat (PPC) was accrescent with 5 erect segments contiguous to the operculum of the seed capsule. This coat forms spongy layers (50 to 300 µm thick) that could be eliminated manually. The narrow internal coat or pericarp or achene coat (AC) forms woody joined seed capsules, each presenting a pressed operculum that cannot be manually opened. This coat was not adherent to seeds and was composed of compressed cells (50 to 200 µm thick) which form pockets for salt cristal. Seeds were lentiform (1 to 2 mm diameter and 0.5 to 0.8 mm thick) and highly fragile. The embryo was whitish surrounded peripherally by the perisperm with two highly developed cotyledons and radical. Polyphenol concentrations in both coats showed that after 4 months of collection, total polyphenol concentrations were 4-fold higher in the pericarp than in the persistent perianth. However, after one year, this parameter decreases significantly in the pericarp, whereas, it increases to a larger extent in the perianth. Different germination tests indicated that the pericarp provides a chemical and a physical resistance to seed germination during the first 4 months of the experiment after collection. The chemical dormancy was released to higher levels of total polyphenol compounds that inhibited seed germination and seedling growth. However, the physical dormancy was associated with the hardness of this intern coat which caused a mechanical resistance to radicle emergence. After one year of storage, total polyphenol pericarp concentration decreased notably, and chemical resistance disappeared, whereas the physical one persisted. Consequently, one year of storage pericarp removal is sufficient to break this exogenous dormancy.

With the increasing climate change crisis, the ongoing global energy security challenges, and the prerequisites for the development of sustainable and affordable energy for all, the need for renewable energy resources has been highlighted as a global aim of mankind. However, the worldwide deployment of renewable energy calls for large-scale financial and technological contributions which many States cannot afford. This exacerbates the need for the promotion of foreign investments in this sector, and protecting them against various threats. International Investment Agreements (IIAs) offer several substantive protections that equally serve foreign investments in this sector. Fair and Equitable Treatment (FET) clauses are among these. This is a flexible standard of treatment whose boundaries are not clearly defined so far. Investment tribunals have diverse views of this standard. Against this background, this article asks: What are the prominent international renewable energy investment threats, and how can FET clauses better contribute to alleviating these concerns? Employing a qualitative method, it analyses the legal aspects and properties of FET and concludes that the growing security and regulatory threats have formed a sort of modern legitimate expectations on the part of renewable energy investors who expect host states to protect them against such threats. Hence, IIAs and tribunals need to uphold a definite and broadly applicable FET approach to bring more consistency and predictability to arbitral awards. This would help deter many unfavourable practices against investments in this sector.

The present study demonstrates the fabrication of heterogeneous ternary composite photocatalysts consisting of TiO₂, kaolinite, and cement (TKCe),which is essential to overcome the practical barriers that are inherent to currently available photocatalysts. TKCe is prepared via a cost-effective method, which involves mechanical compression and thermal activation as major fabrication steps. The clay-cement ratio primarily determines TKCe mechanical strength and photocatalytic efficiency, where TKCe with the optimum clay-cement ratio, which is 1:1, results in a uniform matrix with fewer surface defects. The composites that have a clay-cement ratio below or above the optimum ratio account for comparatively low mechanical strength and photocatalytic activity due to inhomogeneous surfaces with more defects, including particle agglomeration and cracks. The TKCe mechanical strength comes mainly from clay-TiO₂ interactions and TiO₂-cement interactions. TiO₂-cement interactions result in CaTiO₃ formation, which significantly increases matrix interactions; however, the maximum composite performance is observed at the optimum titanate level; anything above or below this level deteriorates composite performance. Over 90% degradation rates are characteristic of all TKCe, which follow pseudo-first-order kinetics in methylene blue decontamination. The highest rate constant is observed with TKCe 1-1, which is 1.57 h⁻¹ and is the highest among all the binary composite photocatalysts that were fabricated previously. The TKCe 1-1 accounts for the highest mechanical strength, which is 6.97 MPa, while the lowest is observed with TKCe 3-1, indicating that the clay-cement ratio has a direct relation to composite strength. TKCe is a potential photocatalyst that can be obtained in variable sizes and shapes, complying with real industrial wastewater treatment requirements.