The present work shows an application of the Chan-Vese algorithm for the semi-automatic segmentation of anatomical structures of interest (lungs and lung tumor) in 4DCT images of the thorax, as well as their three-dimensional reconstruction. The segmentation and reconstruction were performed on 10 CT images, which make up an inspiration-expiration cycle. The maximum displacement was calculated for the case of the lung tumor using the reconstructions of the onset of inspiration, the onset of expiration, and the voxel information. The proposed method achieves appropriate segmentation of the studied structures regardless of their size and shape. The three-dimensional reconstruction allows us to visualize the dynamics of the structures of interest throughout the respiratory cycle. In the future, it is expected to have more evidence of the good performance of the proposed method and to have the feedback of the clinical expert, since the knowledge of the characteristics of anatomical structures, such as their dimension and spatial position, helps in the planning of Radiotherapy (RT) treatments, optimizing the radiation dose to cancer cells and minimizing it in healthy organs. Therefore, the information found in this work may be of interest for the planning of RT treatments.

Using a newly developed data set, we analyze the effects of infrastructure investment on economic performance in Portugal. A vector-autoregressive approach estimates the elasticity and marginal products of twelve types of infrastructure investment on private investment, employment, and output. We find that the largest long-term accumulated effects come from investments in railroads, ports, airports, health, education, and telecommunications. For these infrastructures, the output multipliers suggest that these investments pay for themselves through additional tax revenues. For investments in ports, airports and education infrastructures, the bulk of the effects are short-term demand-side effects, while for railroads, health, and telecommunications, the impact is mostly of a long-term and supply-side nature. Finally, investments in health and airports exhibit decreasing marginal returns, with railroads, ports, and telecommunications being relatively stable. In terms of the other infrastructure assets, the economic effects of investments in municipal roads, electricity and gas, and refineries are insignificant, while investments in national roads, highways, and waste and waste water have positive economic effects but too small to improve the public budget. Clearly, from a policy perspective, not all infrastructure investments in Portugal are created equal.

The paper lays out basic design options for infrastructure policy. It first sketches mechanisms to assess demand. Then it sets out a hierarchy of issues starting with choice of market structure followed by conduct regulation. Ownership options are largely a function of market structure choices. The implications for finance—the topic of much day-to-day discussion in infrastructure policy-making—follow from these various prior choices. The discussion naturally circumscribes the role for the so-called public-private partnerships, their uses and pitfalls.

Infrastructure development policies have been criticised for lacking a deliberate pro-gender and pro-informal sector orientation. Since African economies are dual enclaves, with the traditional and informal sectors female-dominated, failure to have gendered infrastructure development planning and investment exacerbates gender inequality. The paper examines the effect of the infrastructure development index, the size of the informal economy, and the level of economic development on gender inequality. The paper applies the panel autoregressive distributed lag method to data on the gender inequality index, infrastructure development index, GDP per capita, and size of the informal sector for the period 2005–2018. The sample consists of 44 African countries. The research established that the infrastructure development index, its sub-indices, GDP per capita, and the size of the informal sector are crucial dynamics that governments need to consider carefully when formulating development policies to reduce gender inequality. The research found that investment in infrastructure in general, transport infrastructure, and energy infrastructure reduces gender inequality. infrastructure development has gender inequality increasing effects in some countries and gender inequality reducing effects in others. The pattern suggests that at the continental level a Kuznets-type patten in the relationship between gender inequality and infrastructure development, gender inequality and size of informal sector, and gender inequality and GDP per capita exists. Some countries are in the region where changes in these covariates positively correlate with gender inequality, while others are in the region where further increases in the covariates reduce gender inequality.