According to the World Health Organization (WHO), breast cancer is among the most common cancers worldwide. Most of the anticancer agents have been showing a variety of side effects. Recently, bacterial proteins have been investigated as promising anticancer agents. Azurin is a bacterial cupredoxin protein secreted from Pseudomonas aeruginosa and has been reported as a potent multi-targeting anticancer agent, which makes it an appropriate candidate for drug delivery. Azurin may be delivered to cancer cells using different carriers like polymeric micro and nanoparticles. In the present study, azurin was extracted from the bacterial host and loaded into chitosan particles. Then its effect on MCF-7 cell line was investigated. Chitosan-azurin particles were made using the ion gelation method. Results showed that chitosan-azurin particles are about 200 nm, and the loading of the protein in particles did not affect its integrity. The MTT assay showed a significant reduction in cell viability in azurin and chitosan-azurin-treated cells. The toxicity level after 5 days was 63.78% and 82.53% for free azurin and chitosan-azurin-treated cells, respectively. It seems using an appropriate carrier system for anticancer proteins like azurin is a promising tool for developing low side effect anticancer agents.

This contribution aims to appraise, analyze and evaluate the literature relating to the interaction of electromagnetic fields (EMF) with matter and the resulting thermal effects. This relates to the wanted thermal effects via the application of fields as well as those uninvited resulting from exposure to the field. In the paper, the most popular EMF heating technologies are analyzed. This involves on the one hand high frequency induction heating (HFIH) and on the other hand microwave heating (MWH), including microwave ovens and hyperthermia medical treatment. Then, the problem of EMF exposure is examined and the resulting biological thermal effects are illuminated. Thus, the two most common cases of wireless EMF devices, namely digital communication tools and inductive power transfer appliances are analyzed and evaluated. The last part of the paper concerns the determination of the different thermal effects, which are studied and discussed, by considering the governing EMF and heat transfer (or bio heat) equations and their solution methodologies.

There are diverse effects in consequence of exposure to radiofrequency electromagnetic fields (RF-EMF). The interactions of fields and the exposed body tissues are related to the nature of exposure, tissue comportment, field strength and signal frequency. These interactions can crop different effects.

The article focuses on conceptual factors that contribute to the formation of the school as an exemplary educational institution. The questions about effective administration and leadership are answered by analyzing the findings and insights of educational theorists. What are the moral criteria of leadership and the ambiguous and complex decision-making process? How the insights from important work design theories correlate with important conceptual approaches to school management. An important emphasis is placed on diversity and the concept of the school microcosm: how effective administration can increase the self-efficacy of teachers, which in turn always positively affects the academic performance of students. The scientific novelty of the article discusses the views of heads of public schools in Georgia, their subjective experiences, and recommendations, together with the theoretical and conceptual tools of school management. Through the phenomenological analysis conducted with school leaders in Georgia, we will get to know the professional skills and strategies that lead to the strengthening of the school’s pulse and focusing on the so-called “school of the future” model.

Banana macropropagation in a thermal chamber is an economical technology, effective as a phytosanitary cleaning method, and efficient to enhance seedling production. The objective of this work was to evaluate the effects of corm size (CS) and benzylaminopurine (BAP) on plantain cv. Barraganete seedling proliferation in two propagation environments (PE). The treatments consisted of two levels of BAP (with and without BAP), three CS (2 ± 0.5, 4 ± 0.5 and 6 ± 0.5 kg) and two PE (thermal chamber and raised bed). The variables evaluated were sprouting time (days), multiplication rate (MT) per unit (seedlings per corm) and area (seedlings per m²). Sprouting time was significantly influenced (p < 0.05) by the PE, where the thermal chamber advanced shoot emergence by 12 days, with respect to the raised bed. MT of seedlings per corm and m², were significantly influenced (p < 0.05) by BAP × AP and TC × AP interactions, where the highest seedling production per corm occurred inside thermal chamber with BAP and 6 ± 0.5 kg corms, while seedling production per m² was higher with 2 ± 0.5 kg corms under the same thermal chamber conditions and with BAP. The main effects results reported that with BAP there were 30 and 31% increases in MT per corm and per m², respectively, relative to the treatment without BAP. Within the thermal chamber the MT per corm and per m² increased by 44% relative to the raised bed. Regarding the effect of CS, larger corms achieved higher individual MT, while smaller corms achieved higher MT per area. The use of a thermal chamber and BAP is recommended for mass production of banana seedlings through macropropagation.

One of the biggest environmental problems that has affected the planet is global warming, due to high concentrations of carbon (CO₂), which has led to crops such as coffee being affected by climate change caused by greenhouse gases (GHG), especially by the increase in the incidence of pests and diseases. However, carbon sequestration contributes to the mitigation of GHG emissions. The objective of this work was to evaluate the carbon stored in above and below ground biomass in four six-year-old castle coffee production systems. In a trial established under a Randomized Complete Block Design (RCBD) with the treatments Coffee at free exposure (T1), Coffee-Lemon (T2), Coffee-Guamo (T3) and Coffee-Carbonero (T4), at three altitudes: below 1,550 masl, between 1,550 and 2,000 masl and above 2,000 masl. Data were collected corresponding to the stem diameters of coffee seedlings and shade trees with which allometric equations were applied to obtain the carbon variables in the aerial biomass and root and the carbon variables in leaf litter and soil obtained from their dry matter. Highly significant differences were obtained in the four treatments evaluated, with T4 being the one that obtained the highest carbon concentration both in soil biomass with 100.14 t ha^-1 and in aerial biomass with 190.42 t ha^-1.