Researchers from all over the world have been working tirelessly to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic since the World Health Organization (WHO) proclaimed it to be a pandemic in 2019. Expanding testing capacities, creating efficient medications, and creating safe and efficient COVID-19 (SARS CoV-2) vaccinations that provide the human body with long-lasting protection are a few tactics that need to be investigated. In clinical studies, drug delivery techniques, including nanoparticles, have been used since the early 1990s. Since then, as technology has advanced and the need for improved medication delivery has increased, the field of nanomedicine has recently seen significant development. PNPs, or polymeric nanoparticles, are solid particles or particulate dispersions that range in size from 10 to 1000 nm, and their ability to efficiently deliver therapeutics to specific targets makes them ideal drug carriers. This review article discusses the many polymeric nanoparticle (PNP) platforms developed to counteract the recent COVID-19 pandemic-related severe acute respiratory syndrome coronavirus (SARS-CoV-2). The primary subjects of this article are the size, shape, cytotoxicity, and release mechanism of each nanoparticle. The two kinds of preparation methods in the synthesis of polymeric nanoparticles have been discussed: the first group uses premade polymers, while the other group depends on the direct polymerization of monomers. A few of the PNPs that have been utilized to combat previous viral outbreaks against SARS-CoV-2 are also covered.

In recent years, the pathological diagnosis of glomerular diseases typically involves the study of glomerular his-to pathology by specialized pathologists, who analyze tissue sections stained with Periodic Acid-Schiff (PAS) to assess tissue and cellular abnormalities. In recent years, the rapid development of generative adversarial networks composed of generators and discriminators has led to further developments in image colorization tasks. In this paper, we present a generative adversarial network by Spectral Normalization colorization designed for color restoration of grayscale images depicting glomerular cell tissue elements. The network consists of two structures: the generator and the discriminator. The generator incorporates a U-shaped decoder and encoder network to extract feature information from input images, extract features from Lab color space images, and predict color distribution. The discriminator network is responsible for optimizing the generated colorized images by comparing them with real stained images. On the Human Biomolecular Atlas Program (HubMAP)—Hacking the Kidney FTU segmentation challenge dataset, we achieved a peak signal-to-noise ratio of 29.802 dB, along with high structural similarity results as other colorization methods. This colorization method offers an approach to add color to grayscale images of glomerular cell tissue units. It facilitates the observation of physiological information in pathological images by doctors and patients, enabling better pathological-assisted diagnosis of certain kidney diseases.

This report intends to enhance the reviews on leadership literature by conducting a bibliometric study on 198 publications focused on transformational leadership research. These papers were published in the Scopus database between 1997 and 2023. Employing quantitative bibliometric analysis, the study aims to identify both current and prospective research trajectories pertaining to transformational leadership issues. To the best of our current understanding, there exists no scholarly investigation that examines the bibliographic data pertaining to transformational leadership domains. Therefore, this work represents a distinctive and original contribution to the existing body of literature. This study additionally offers a comprehensive examination of the patterns and paths inside a visual and schematic framework for the investigation of this subject matter. This may facilitate researchers in comprehending the prevailing patterns and prospective avenues for research, so empowering future authors to carry out their investigations with greater efficacy. There exists a number of underexplored themes or subjects pertaining to transformational leadership matters, such as knowledge sharing, leadership styles, digital transformation, innovative work behavior, competitive advantage and digital transformation. This discovery offers useful insights into the heterogeneous nature of this area across multiple disciplines.

A total of 25 SSR primers were screened on 37 putative F₁s derived from the five different crosses. Identified cross specific highly informative SSRs primers, i.e., 14 for the first cross, 10 for the second, 12 for the third and 6 each for fourth and fifth crosses. For the first cross Bhagwa × Daru 17, four primers (HvSSRT_375, NRCP_SSR9, NRCP_SSR12 and NRCP_SSR92) were found to be highly informative with higher 100% hybrid purity index (HPI), PIC (~0.52), and observed heterozygosity (Ho, range 0.87–0.93) values, and two F₁s namely H₁ and H₂ were found to be highly heterotic with a heterozygosity index (HI) of 92.85%. Similarly, for Bhagwa × Nana, three primers (HvSSRT_375, HvSSRT_605 and NRCP_SSR19) had higher HPI (70%–100%), PIC (0.52–0.69), and Ho (0.75–0.33) values, and three F₁s H₁, H₂, and H₄ had 70% (HI). For Bhagwa × IC318712, four SSRs (HvSSRT_254, HvSSRT_348, HvSSRT_826 and NRCP_SSR95) had higher Ho (~0.83), HPI (100%) and PIC (~0.52) values, and four F₁s H₂, H₇, H₉, and H₁₀ showed 91.66% (HI). For Bhagwa × Nayana, HvSSRT_605, HvSSRT_826, and HvSSRT_432, and for Ganesh × Nayana, HVSSRT_375, HVSSRT_605, and HvSSRT_826 were found informative. These markers will be highly useful in developing maps of populations.

Given the growing significance of the metaverse in research, it is crucial to understand its scope, relevance in the tourism industry, and the human-computer interaction it involves. The emerging field of metaverse tourism has a noticeable research gap, limiting a comprehensive understanding of the concept. This article addresses this gap by conducting a hybrid systematic review, including a variable-oriented literature review, to assess the extent and scope of metaverse tourism. A scrutiny on Scopus identified a reduced number of relevant documents. The analysis exposes theoretical and empirical gaps, along with promising opportunities in the metaverse and tourism intersection. These insights contribute to shaping a contemporary research agenda, emphasizing metaverse tourism. While this study offers an overview of current research in metaverse tourism, it is essential to recognize that this field is still in its early stages, marked by the convergence of technology and transformations in tourism. This exploration underscores the challenges and opportunities arising from the evolving narrative of metaverse tourism.

The use of plant viruses as bioherbicides represents a fascinating and promising frontier in modern agriculture and weed management. This review article delves into the multifaceted world of harnessing plant viruses for herbicidal purposes, shedding light on their potential as eco-friendly, sustainable alternatives to traditional chemical herbicides. We begin by exploring the diverse mechanisms through which plant viruses can target and control weeds, from altering gene expression to disrupting essential physiological processes. The article highlights the advantages of utilizing plant viruses, such as their specificity for weed species, minimal impact on non-target plants, and a reduced environmental footprint. Furthermore, we investigate the remarkable versatility of plant viruses, showcasing their adaptability to various weed species and agricultural environments. The review delves into the latest advancements in genetic modification techniques, which enable the engineering of plant viruses for enhanced herbicidal properties and safety. In addition to their efficacy, we discuss the economic and ecological advantages of using plant viruses as bioherbicides, emphasizing their potential to reduce chemical herbicide usage and decrease the development of herbicide-resistant weeds. We also address the regulatory and safety considerations associated with the application of plant viruses in agriculture. Ultimately, this review article underscores the immense potential of plant viruses as bioherbicides and calls for further research, development, and responsible deployment to harness these microscopic agents in the ongoing quest for sustainable and environmentally friendly weed management strategies.