Business ethics plays a crucial role in developing modern business and the entire society. Thus, to develop the conceptual framework of business ethics, it is extremely interesting to study the concepts connected with it. The article identifies the main terms and concepts associated with business ethics. On this basis, the authors’ conceptual framework of business ethics was created. Within this conceptual framework, it is shown that each business unit builds and maintains relationships with stakeholders within two “circles of business ethics”: the inner circle of business ethics and the outer circle of business ethics. The article proves the hypothesis that business ethics should be considered in the context of relationships with all stakeholders, i.e., it is the ethics of business relationships with partners and competitors in the external environment, as well as within the internal environment (primarily with employees). The article will be of interest to specialists in the field of management, and corporate governance, as well as for anyone interested in the problems of corporate social management.

Urban infrastructures and services—such as public transportation, innovation bodies and environmental services—are important drivers for the sustainable development of our society. How effectively citizens, institutions and enterprises interact, how quickly technological innovations are implemented and how carefully new policies are pursued, synergically determine development. In this work, data related to urban infrastructure features such as patents and recycled waste referred to 106 province areas in Italy are investigated over a period of twenty years (2001–2020). Scaling laws with exponents characterizing the above mentioned features are observed and adopted to scrutinize whether and how multiple interactions within a population have amplification effects on the recycling and innovation performance. The study shows that there is a multiplication effect of the population size on the innovation performance of territories, meaning that the dynamic interactions among the elements of the innovation eco-systems in a territory increase its innovation performance. We discuss how to use such approach and the related indexes for understanding metropolitan development policy.

High-quality development in China requires higher vocational education, scientific and technological innovation, and sustainable economic development. The spatial distribution patterns of these factors show higher levels in the east and coastal areas compared to the west and inland regions, emphasizing the need for coupling coordination with the social economy. This study examines the impact of sustainable economic development on the coupling coordination degree using the spatial Durbin model. The results show a positive promotion and spillover effect, with regional variations. The main factors affecting the difference in coupling coordination are the amount of technology market contracts, fiscal expenditure on science and technology, patent application authorizations, tertiary industry output value, and the number of R&D institutions. According to the grey prediction model, the coupling coordination degree is expected to increase from 2022 to 2025, but achieving primary coordination may still be challenging in some areas. Therefore, strategies that utilize regional characteristics for coordinated development should be developed to improve the level of coupling coordination and create a mutually beneficial environment.

This paper provides a comparative perspective on infrastructure provision in developing Asia's three largest countries: China, India, and Indonesia. It discusses their achievements and shortfalls in providing network infrastructure (energy, transport, water, and telecommunications) over the past two decades. It documents how three quite distinct development paths—and very different levels of national saving and investment—were manifested in different trajectories of infrastructure provision. The paper then describes the institutional, economic, and policy factors that enabled or hindered progress in providing infrastructure. Here, contrasting levels of centralization of planning played a key role, as did countries’ differing abilities to mobilize infrastructure-related revenue streams such as user charges and land value capture. The paper then assesses future challenges for the three countries in providing infrastructure in a more integrated and sustainable way, and links these challenges with the global development agenda to which the three countries have committed. The concluding recommendations hope to provide a platform for further policy and research dialogue.

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Cisplatin-loaded nanoparticle formulations were optimized utilizing response surface methods and the central composite rotating design model. This study employed a central composite rotatable design with a three-factored factorial design with three tiers. Three independent variables namely drug polymer ratio, aqueous organic phase ration, and stabilizer concentration were used to examine the particle size, entrapment efficiency, and drug loading of cisplatin PLGA nanoparticles as responses. The results revealed that this response surface approach might be able to be used to find the best formulation for the cisplatin PLGA nanoparticles. A polymer ratio of 1:8.27, organic phase ratio of 1:6, and stabilizer concentration of 0.15 were found to be optimum for cisplatin PLGA nanoparticles. Nanoparticles made under the optimal conditions found yielded a 112 nm particle size and a 95.4 percent entrapment efficiency, as well as a drug loading of 9 percent. The cisplatin PLGA nanoparticles tailored for scanning electon microscopy displayed a spherical form. A series of in vitro tests showed that the nanoparticle delivered cisplatin progressively over time. According to this work, the Response Surface Methodology (RSM) employing the central composite rotatable design may be successfully used to simulate cisplatin-PLGA nanoparticles.