Objective: To investigate the value of differential diagnosis of hepatocellular carcinoma (HCC) and cirrhotic nodules via radiomics models based on magnetic resonance images. Background: This study is to distinguish hepatocellular carcinoma and cirrhotic nodules using MR-radiomics features extracted from four different phases of MRI images, concluded T1WI, T2WI, T2 SPIR and delay phase of contrast MRI. Methods: In this study, the four kind of magnetic resonance images of 23 patients with hepatocellular carcinoma (HCC) were collected. Among them, 12 patients with liver cirrhosis were used to obtain cirrhotic nodules (CN). The dataset was used to extract MR-radiomics features from regions of interest (ROI). The statistical methods of MRradiomics features could distinguish HCC and CN. And the ability of radiomics features between HCC and CN was estimated by receiver operating characteristic curve (ROC). Results: A total of 424 radiomics features were extracted from four kind of magnetic resonance images. 86 features in delay phase of contrast MRI,86 features in spir phase of T2WI,86 features in T1WI and 88 features in T2WI showed statistical difference (p < 0.05). Among them, the area under the curves (AUC) of these features larger than 0.85 were 58 features in delay phase of contrast MRI, 54 features in spir phase of T2WI, 62 features in T1WI and 57 features in T2WI. Conclusions: Radiomics features extracted from MRI images have the potential to distinguish HCC and CN.
Concession agreements (CAs) in the port sector are designed to establish mutually beneficial arrangements for involved parties. They serve as catalysts, enabling ports to attract adept private investors and secure requisite funding to enhance port infrastructure, superstructure, and service quality. Concurrently, the imperative to mitigate negative externalities and promote sustainable practices in port organization and development remains paramount. In this context, the paper explores the nuanced landscape of CAs, specifically focusing on the urgent need for an innovative framework that integrates sustainability within port organization, operations and development. Drawing from existing academic discourse and field evidence, it systematically identifies, examines, and analyzes fundamental requirements and key factors that should be considered in CAs, in line with sustainable development and proposes a reference framework for an ideal Concession Agreement model. Despite evident strengthening of sustainability implications in port concessions, significant room for improvement persists. Nevertheless, dynamics in the field create a certain optimism for the future.
This study addresses the impact of the tourism sector on poverty, poverty depth, and poverty severity in Indonesia, focusing on the micro-level dynamics in the province. Despite numerous tourism destinations, their strategic contribution to regional progress remains underexplored. The motivation stems from the need to comprehend the nuanced relationship between tourism and poverty at both the national and local levels, with specific attention to the untapped potential at the province level in Indonesia. We hypothesize that a higher tourism sector GRDP will be inversely correlated with poverty levels, and the inclusion of a Covid-19 variable will reveal a structural impact on poverty dynamics. Employing a Panel Regression Model, secondary data from the Central Statistics Agency (BPS) spanning 2011–2020 is utilized. A panel data regression equation model, including CEM, FEM, and REM, is employed to analyze the intricate relationship between tourism and poverty. The findings demonstrate a negative correlation between higher tourism sector GRDP and the number of poor people. The Covid-19 variable, considered a structural break, reveals a significant association between increased cases and elevated poverty and severity across Indonesian provinces. This study contributes a micro-level analysis of tourism’s role, emphasizing its impact at the provincial level. The findings underscore the need for strategic initiatives to harness the untapped potential of tourism in alleviating poverty and promoting regional progress.
The current era of Industry 4.0, driven by advanced technologies, holds immense potential for revolutionising various industries and fostering substantial economic growth. However, comprehending intricate processes of policy change poses difficulties, impeding necessary adaptations. Public apprehensions are growing about the inertia and efficacy of policy changes, given the influential role of policy environments in shaping development amidst resource constraints. To address these concerns, the study introduces the Kaleidoscope Model of policy change, serving as a roadmap for policymakers to enact effective changes. The study investigates the mediating impact of cultural change within the framework of the Kaleidoscope Model. The study delves into cultural influences by incorporating the Behavior Change Wheel (BCW) Theory. The methodology involves questionnaires survey, analysing using Structural Equation Modelling (SEM). The findings reveal that only the Policy Adoption and Policy Implementation components significantly affect the assessment of the effectiveness of the Construction 4.0 policy. Intriguingly, the final model demonstrates no discernible connection between the Kaleidoscope Model and the cultural influences. This study makes a noteworthy contribution to the realm of political science by furnishing a comprehensive framework and directives for the successful implementation of the Construction 4.0 policy.
Scientists have harnessed the diverse capabilities of nanofluids to solve a variety of engineering and scientific problems due to high-temperature predictions. The contribution of nanoparticles is often discussed in thermal devices, chemical reactions, automobile engines, fusion processes, energy results, and many industrial systems based on unique heat transfer results. Examining bioconvection in non-Newtonian nanofluids reveals diverse applications in advanced fields such as biotechnology, biomechanics, microbiology, computational biology, and medicine. This study investigates the enhancement of heat transfer with the impact of magnetic forces on a linearly stretched surface, examining the two-dimensional Darcy-Forchheimer flow of nanofluids based on blood. The research explores the influence of velocity, temperature, concentration, and microorganism profile on fluid flow assumptions. This investigation utilizes blood as the primary fluid for nanofluids, introducing nanoparticles like zinc oxide and titanium dioxide (. The study aims to explore their interactions and potential applications in the field of biomedicine. In order to streamline the complex scheme of partial differential equations (PDEs), boundary layer assumptions are employed. Through appropriate transformations, the governing partial differential equations (PDEs) and their associated boundary conditions are transformed into a dimensionless representation. By employing a local non-similarity technique with a second-degree truncation and utilizing MATLAB’s built-in finite difference code (bvp4c), the modified model’s outcomes are obtained. Once the calculated results and published results are satisfactorily aligned, graphical representations are used to illustrate and analyze how changing variables affect the fluid flow characteristics problems under consideration. In order to visualize the numerical variations of the drag coefficient and the Nusselt number, tables have been specially designed. Velocity profile of -blood and -blood decreases for increasing values of and , while temperature profile increases for increasing values of and . Concentration profile decreases for increasing values of , and microorganism profile increases for increasing values of . For rising values of and the drag coefficient increases and the Nusselt number decreases for rising values of and The model introduces a novel approach by conducting a non-similar analysis of the Darchy-Forchheimer bioconvection flow of a two-dimensional blood-based nanofluid in the presence of a magnetic field.
The current paper aims at spatial presentation in Cinque Terre. The purpose is to reconstruct digital products (maps, statistics, diagrams, and 3D models) and the spatial analysis of the five villages. The goals are the presentation of the geomorphology, geography, population, density, and area. Also, the Strength-Weakness-Opportunities-Threats (SWOT) analysis creates the disadvantages and advantages of the five villages in the region. The methodology is based on the software (G.I.S. Pro, QGIS, Zephyr 3D, Microsoft Excel, Generic Mapping Tool) and the bibliography study. For instance, the construction 3D terrain model shows the buildings, roads, green areas, and land cover of the five villages. The digital products help better “read” the region and emphasize the measurements and location of the region’s elements. The final results contain a message about new technologies and spatial planning. The new technologies have given spatial solutions in the last few years. The innovative, understanding, and attractive cartographical digital products present the geomorphology of the traditional villages in Cinque Terre.
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