Cancer is the 3rd leading cause of death globally, and the countries with low-to-middle income account for most cancer cases. The current diagnostic tools, including imaging, molecular detection, and immune histochemistry (IHC), have intrinsic limitations, such as poor accuracy. However, researchers have been working to improve anti-cancer treatment using different drug delivery systems (DDS) to target tumor cells more precisely. Current advances, however, are enough to meet the growing call for more efficient drug delivery systems, but the adverse effects of these systems are a major problem. Nanorobots are typically controlled devices made up of nanometric component assemblies that can interact with and even diffuse the cellular membrane due to their small size, offering a direct channel to the cellular level. The nanorobots improve treatment efficiency by performing advanced biomedical therapies using minimally invasive operations. Chemotherapy’s harsh side effects and untargeted drug distribution necessitate new cancer treatment trials. The nanorobots are currently designed to recognize 12 different types of cancer cells. Nanorobots are an emerging field of nanotechnology with nanoscale dimensions and are predictable to work at an atomic, molecular, and cellular level. Nanorobots to date are under the line of investigation, but some primary molecular models of these medically programmable machines have been tested. This review on nanorobots presents the various aspects allied, i.e., introduction, history, ideal characteristics, approaches in nanorobots, basis for the development, tool kit recognition and retrieval from the body, and application considering diagnosis and treatment.
Urban infrastructures and services—such as public transportation, innovation bodies and environmental services—are important drivers for the sustainable development of our society. How effectively citizens, institutions and enterprises interact, how quickly technological innovations are implemented and how carefully new policies are pursued, synergically determine development. In this work, data related to urban infrastructure features such as patents and recycled waste referred to 106 province areas in Italy are investigated over a period of twenty years (2001–2020). Scaling laws with exponents characterizing the above mentioned features are observed and adopted to scrutinize whether and how multiple interactions within a population have amplification effects on the recycling and innovation performance. The study shows that there is a multiplication effect of the population size on the innovation performance of territories, meaning that the dynamic interactions among the elements of the innovation eco-systems in a territory increase its innovation performance. We discuss how to use such approach and the related indexes for understanding metropolitan development policy.
In the face of growing disruptions within the unconventional business environment, this study focuses on enhancing supply chain resilience through strategically reforming resources. It highlights the importance of understanding the dynamics and interactions of resources to tackle supply chain vulnerability (SCV) in the manufacturing sector. Employing the Decision-Making Trial and Evaluation Laboratory (DEMATEL) methodology alongside an adapted Analytic Network Process (ANP), the research investigates supply chain vulnerabilities in Pakistan’s large-scale manufacturing (LSM) public sector firms. The DANP method, through expert questionnaires, helps validate a theoretical framework by assessing the interconnectedness of supply chain readiness dimensions and criteria. Findings underscore Resource Reformation (RR) as a critical dimension, with the positive restructuring of resources identified as pivotal for public sector firms to align their operations with disruption magnitudes, advocating for a detailed analysis of resource utilization.
Freshwater problems in coastal areas include the process of salt intrusion which occurs due to decreasing groundwater levels below sea level which can cause an increase in salt levels in groundwater so that the water cannot be used for water purposes, human consumption and agricultural needs. The main objective of this research is to implementation of RWH to fulfill clean water needs in tropical coastal area in Tanah Merah Village, Indragiri Hilir Regency, with the aim of providing clean water to coastal communities. The approach method used based on fuzzy logic (FL). The model input data includes the effective area of the house’s roof, annual rainfall, roof runoff coefficient, and water consumption based on the number of families. The BWS III Sumatera provided the rainfall data for this research, which was collected from the Keritang rainfall monitoring station during 2015 and 2021. The research findings show that FL based on household scale RWH technology is used to supply clean water in tropical coastal areas that the largest rainwater contribution for the 144 m2 house type for the number of residents in a house of four people with a tank capacity of 29 m2 is 99.45%.
This study aims to examine the entrepreneurial activities of 240 women in the districts of Konaseema, East Godavari, and Kakinada during 2021–2022, focusing on the diverse range of 286 enterprises they managed across 69 business types. These enterprises were tailored to local resources and market demands, with coconut wholesale, cattle breeding, and provision shops being the most common. The study also analyzes income distribution, noting that one-third of the women earned between ₹50,000–1,00,000 annually, while only 0.70% earned over ₹5,00,000. More than half of the enterprises served as the primary income source for their families. The research highlights the significant role these women entrepreneurs play in their communities, their job satisfaction derived from financial independence and social empowerment, and the challenges they face, such as limited capital and market access. Finally, the study offers recommendations to empower these women to seize entrepreneurial opportunities and enhance their success.
The economy, unemployment, and job creation of South Africa heavily depend on the growth of the agricultural sector. With a growing population of 60 million, there are approximately 4 million small-scale farmers (SSF) number, and about 36,000 commercial farmers which serve South Africa. The agricultural sector in South Africa faces challenges such as climate change, lack of access to infrastructure and training, high labour costs, limited access to modern technology, and resource constraints. Precision agriculture (PA) using AI can address many of these issues for small-scale farmers by improving access to technology, reducing production costs, enhancing skills and training, improving data management, and providing better irrigation infrastructure and transport access. However, there is a dearth of research on the application of precision agriculture using artificial intelligence (AI) by small scale farmers (SSF) in South Africa and Africa at large. The preferred reporting items for systematic reviews and meta-analyses (PRISMA) and Bibliometric analysis guidelines were used to investigate the adoption of precision agriculture and its socio-economic implications for small-scale farmers in South Africa or the systematic literature review (SLR) compared various challenges and the use of PA and AI for small-scale farmers. The incorporation of AI-driven PA offers a significant increase in productivity and efficiency. Through a detailed systematic review of existing literature from inception to date, this study examines 182 articles synthesized from two major databases (Scopus and Web of Science). The systematic review was conducted using the machine learning tool R Studio. The study analyzed the literature review articled identified, challenges, and potential societal impact of AI-driven precision agriculture.
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